Secondary vitreoretinal lymphoma with spontaneous regression.
Large B-cell lymphoma
Multimodal imaging
Recurrence
Spontaneous regression
Vitreoretinal lymphoma
Journal
American journal of ophthalmology case reports
ISSN: 2451-9936
Titre abrégé: Am J Ophthalmol Case Rep
Pays: United States
ID NLM: 101679941
Informations de publication
Date de publication:
Mar 2022
Mar 2022
Historique:
received:
30
04
2021
revised:
20
09
2021
accepted:
22
01
2022
entrez:
11
2
2022
pubmed:
12
2
2022
medline:
12
2
2022
Statut:
epublish
Résumé
To report a patient with vitreoretinal lymphoma (VRL) secondary to systemic diffuse large B-cell lymphoma, who had two episodes of spontaneous regression. An 80-year-old Nicaraguan male with a history of treated systemic diffuse large B-cell lymphoma presented with decreased vision in his right eye over one year. The patient was found to have subretinal lesions and moderate vitreous opacities in his right eye. Cytological analysis of vitreous confirmed B-cell lymphoma. Following his systemic work-up, spontaneous clinical improvement was noted. There were no vitreoretinal or systemic lymphoma recurrences during one year of follow-up until the patient had new onset decreased vision in the left eye. He was presumed to have a recurrence of VRL supported by optical coherence tomography findings. Repeat systemic workup was negative for reoccurrence and the ocular lesions resolved spontaneously over 4 weeks. Spontaneous regression of intraocular lymphoma can rarely occur. Multimodal imaging has an essential role in diagnosing and monitoring recurrence of this disease.
Identifiants
pubmed: 35146209
doi: 10.1016/j.ajoc.2022.101357
pii: S2451-9936(22)00103-7
pmc: PMC8818703
doi:
Types de publication
Case Reports
Langues
eng
Pagination
101357Informations de copyright
© 2022 Published by Elsevier Inc.
Déclaration de conflit d'intérêts
The following authors have no financial disclosures: WK, AK, JS, HW, HNS, SK.
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