PEG-Functionalized Magnetite Nanoparticles for Modulation of Microbial Biofilms on Voice Prosthesis.

PEG antibiofilm activity antimicrobial coatings antimicrobial resistance magnetite nanoparticles matrix assisted pulsed laser evaporation polymyxin B

Journal

Antibiotics (Basel, Switzerland)
ISSN: 2079-6382
Titre abrégé: Antibiotics (Basel)
Pays: Switzerland
ID NLM: 101637404

Informations de publication

Date de publication:
29 Dec 2021
Historique:
received: 11 12 2021
revised: 24 12 2021
accepted: 27 12 2021
entrez: 21 1 2022
pubmed: 22 1 2022
medline: 22 1 2022
Statut: epublish

Résumé

This study reports the fabrication of nanostructured coatings based on magnetite, polyethyleneglycol, and biologically active molecule (polymyxin B-PM) for producing biofilm-resistant surfaces (voice prosthesis). Magnetite nanoparticles (MNPs) have been synthesized and functionalized using a co-precipitation method and were further deposited into thin coatings using the matrix-assisted pulsed laser evaporation (MAPLE) technique. The obtained nanoparticles and coatings were characterized by X-ray diffraction (XRD), thermogravimetric analysis with differential scanning calorimetry (TGA-DSC), scanning electron microscopy (SEM), transmission electron microscopy with selected area electron diffraction (TEM-SAED), Fourier-transform infrared spectroscopy (FT-IR), and infrared microscopy (IRM). Their antibiofilm activity was tested against relevant

Identifiants

pubmed: 35052915
pii: antibiotics11010039
doi: 10.3390/antibiotics11010039
pmc: PMC8773041
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Mara Caciandone (M)

"Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.

Adelina-Gabriela Niculescu (AG)

Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, Politehnica University of Bucharest, 011061 Bucharest, Romania.

Aurelian Radu Roșu (AR)

Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, Politehnica University of Bucharest, 011061 Bucharest, Romania.

Valentina Grumezescu (V)

Lasers Department, National Institute for Lasers, Plasma and Radiation Physics, 077125 Magurele, Romania.

Irina Negut (I)

Lasers Department, National Institute for Lasers, Plasma and Radiation Physics, 077125 Magurele, Romania.

Alina Maria Holban (AM)

Department of Microbiology and Immunology, Faculty of Biology, University of Bucharest, 077206 Bucharest, Romania.
Research Institute of the University of Bucharest-ICUB, University of Bucharest, 050657 Bucharest, Romania.

Ovidiu Oprea (O)

Department of Inorganic Chemistry, Physical Chemistry and Electrochemistry, Faculty of Applied Chemistry and Materials Science, Politehnica University of Bucharest, 011061 Bucharest, Romania.

Bogdan Ștefan Vasile (BȘ)

Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, Politehnica University of Bucharest, 011061 Bucharest, Romania.

Alexandra Cătălina Bîrcă (AC)

Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, Politehnica University of Bucharest, 011061 Bucharest, Romania.

Alexandru Mihai Grumezescu (AM)

Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, Politehnica University of Bucharest, 011061 Bucharest, Romania.
Research Institute of the University of Bucharest-ICUB, University of Bucharest, 050657 Bucharest, Romania.
Academy of Romanian Scientists, Ilfov No. 3, 050044 Bucharest, Romania.

Miruna Silvia Stan (MS)

Academy of Romanian Scientists, Ilfov No. 3, 050044 Bucharest, Romania.
Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Bucharest, 050095 Bucharest, Romania.

Alina Georgiana Anghel (AG)

"Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
ENT Department, Saint Mary Clinical Hospital Bucharest, 011172 Bucharest, Romania.

Ion Anghel (I)

"Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
"Dr. Carol Davila" Central Military Emergency University Hospital, 010825 Bucharest, Romania.

Classifications MeSH