Emergence and patterning dynamics of mouse-definitive endoderm.
Developmental genetics
Embryology
Journal
iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038
Informations de publication
Date de publication:
21 Jan 2022
21 Jan 2022
Historique:
received:
11
05
2021
revised:
21
10
2021
accepted:
01
12
2021
entrez:
6
1
2022
pubmed:
7
1
2022
medline:
7
1
2022
Statut:
epublish
Résumé
The segregation of definitive endoderm (DE) from bipotent mesendoderm progenitors leads to the formation of two distinct germ layers. Dissecting DE commitment and onset has been challenging as it occurs within a narrow spatiotemporal window in the embryo. Here, we employ a dual Bra/Sox17 reporter cell line to study DE onset dynamics. We find Sox17 expression initiates
Identifiants
pubmed: 34988400
doi: 10.1016/j.isci.2021.103556
pii: S2589-0042(21)01526-1
pmc: PMC8693470
doi:
Types de publication
Journal Article
Langues
eng
Pagination
103556Informations de copyright
© 2021 The Authors.
Déclaration de conflit d'intérêts
The authors declare no competing interests.
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