Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses.

Journal

bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187

Informations de publication

Date de publication:
22 Dec 2021
Historique:
entrez: 4 1 2022
pubmed: 5 1 2022
medline: 5 1 2022
Statut: epublish

Résumé

On the 24

Identifiants

DOI: 10.1101/2021.12.03.471045 PMID: 34981049 PMC: PMC8722586
pubmed: 34981049
doi: 10.1101/2021.12.03.471045
pmc: PMC8722586
pii:
doi:

Types de publication

Preprint

Langues

eng

Subventions

Organisme : Medical Research Council
ID : MR/V028448/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_PC_20060
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_PC_19025
Pays : United Kingdom
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_PC_19059
Pays : United Kingdom
Organisme : Bill & Melinda Gates Foundation
ID : INV-016202
Pays : United States

Commentaires et corrections

Type : UpdateIn

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Auteurs

Wanwisa Dejnirattisai (W)

Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Jiandong Huo (J)

Division of Structural Biology, Nuffield Department of Medicine, University of Oxford, The Wellcome Centre for Human Genetics, Oxford, UK.

Daming Zhou (D)

Division of Structural Biology, Nuffield Department of Medicine, University of Oxford, The Wellcome Centre for Human Genetics, Oxford, UK.
Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.

Jiří Zahradník (J)

Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.

Piyada Supasa (P)

Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Chang Liu (C)

Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.

Helen M E Duyvesteyn (HME)

Division of Structural Biology, Nuffield Department of Medicine, University of Oxford, The Wellcome Centre for Human Genetics, Oxford, UK.

Helen M Ginn (HM)

Diamond Light Source Ltd, Harwell Science & Innovation Campus, Didcot, UK.

Alexander J Mentzer (AJ)

Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

Aekkachai Tuekprakhon (A)

Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Rungtiwa Nutalai (R)

Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Beibei Wang (B)

Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Aiste Dijokaite (A)

Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Suman Khan (S)

Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.

Ori Avinoam (O)

Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.

Mohammad Bahar (M)

Division of Structural Biology, Nuffield Department of Medicine, University of Oxford, The Wellcome Centre for Human Genetics, Oxford, UK.

Donal Skelly (D)

Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Peter Medawar Building for Pathogen Research, Oxford, UK.
Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.

Sandra Adele (S)

Peter Medawar Building for Pathogen Research, Oxford, UK.

Sile Ann Johnson (SA)

Peter Medawar Building for Pathogen Research, Oxford, UK.

Ali Amini (A)

Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Translational Gastroenterology Unit, University of Oxford, Oxford, UK.
Peter Medawar Building for Pathogen Research, Oxford, UK.

Thomas Ritter (T)

Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

Chris Mason (C)

Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

Christina Dold (C)

NIHR Oxford Biomedical Research Centre, Oxford, UK.
Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.

Daniel Pan (D)

Department of Infectious Diseases and HIV Medicine, University Hospitals of Leicester NHS Trust.
Department of Respiratory Sciences, University of Leicester.

Sara Assadi (S)

Department of Infectious Diseases and HIV Medicine, University Hospitals of Leicester NHS Trust.

Adam Bellass (A)

Department of Infectious Diseases and HIV Medicine, University Hospitals of Leicester NHS Trust.

Nikki Omo-Dare (N)

Department of Infectious Diseases and HIV Medicine, University Hospitals of Leicester NHS Trust.

David Koeckerling (D)

Medical Sciences Division, University of Oxford.

Amy Flaxman (A)

Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Daniel Jenkin (D)

Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Parvinder K Aley (PK)

Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.

Merryn Voysey (M)

Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.

Sue Ann Costa Clemens (SAC)

Institute of Global Health, University of Siena, Siena, Brazil; Department of Paediatrics, University of Oxford, Oxford, UK.

Felipe Gomes Naveca (FG)

Laboratório de Ecologia de Doenças Transmissíveis na Amazônia, Instituto Leônidas e Maria Deane, Fiocruz, Manaus, Amazonas, Brazil.

Valdinete Nascimento (V)

Laboratório de Ecologia de Doenças Transmissíveis na Amazônia, Instituto Leônidas e Maria Deane, Fiocruz, Manaus, Amazonas, Brazil.

Fernanda Nascimento (F)

Laboratório de Ecologia de Doenças Transmissíveis na Amazônia, Instituto Leônidas e Maria Deane, Fiocruz, Manaus, Amazonas, Brazil.

Cristiano Fernandes da Costa (C)

Fundação de Vigilância em Saúde do Amazonas, Manaus, Amazonas, Brazil.

Paola Cristina Resende (PC)

Laboratorio de vírus respiratórios- IOC/FIOCRUZ, Rio de Janeiro, Brazil.

Alex Pauvolid-Correa (A)

Laboratorio de vírus respiratórios- IOC/FIOCRUZ, Rio de Janeiro, Brazil.
Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, TX, United States.

Marilda M Siqueira (MM)

Laboratorio de vírus respiratórios- IOC/FIOCRUZ, Rio de Janeiro, Brazil.

Vicky Baillie (V)

South African Medical Research Council, Vaccines and Infectious Diseases Analytics Research Unit, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Department of Science and Technology/National Research Foundation, South African Research Chair Initiative in Vaccine Preventable Diseases, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Natali Serafin (N)

South African Medical Research Council, Vaccines and Infectious Diseases Analytics Research Unit, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Department of Science and Technology/National Research Foundation, South African Research Chair Initiative in Vaccine Preventable Diseases, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Zanele Ditse (Z)

South African Medical Research Council, Vaccines and Infectious Diseases Analytics Research Unit, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Department of Science and Technology/National Research Foundation, South African Research Chair Initiative in Vaccine Preventable Diseases, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Kelly Da Silva (K)

South African Medical Research Council, Vaccines and Infectious Diseases Analytics Research Unit, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Department of Science and Technology/National Research Foundation, South African Research Chair Initiative in Vaccine Preventable Diseases, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Shabir Madhi (S)

South African Medical Research Council, Vaccines and Infectious Diseases Analytics Research Unit, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Department of Science and Technology/National Research Foundation, South African Research Chair Initiative in Vaccine Preventable Diseases, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Marta C Nunes (MC)

South African Medical Research Council, Vaccines and Infectious Diseases Analytics Research Unit, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Department of Science and Technology/National Research Foundation, South African Research Chair Initiative in Vaccine Preventable Diseases, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Tariq Malik (T)

National Infection Service, Public Health England (PHE), Porton Down, Salisbury, UK.

Peter Jm Openshaw (PJ)

National Heart & Lung Institute, Imperial College London.

J Kenneth Baillie (JK)

Genetics and Genomics, Roslin Institute, University of Edinburgh, Edinburgh, UK.

Malcolm G Semple (MG)

NIHR Health Protection Research Unit, Institute of Infection, Veterinary and Ecological Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK.

Alain R Townsend (AR)

Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.
MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DS, UK.

Kuan-Ying A Huang (KA)

Research Center for Emerging Viral Infections, College of Medicine, Chang Gung University, Taoyuan, Taiwan.

Tiong Kit Tan (TK)

MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DS, UK.

Miles W Carroll (MW)

Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
National Infection Service, Public Health England (PHE), Porton Down, Salisbury, UK.

Paul Klenerman (P)

Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Peter Medawar Building for Pathogen Research, Oxford, UK.
Translational Gastroenterology Unit, University of Oxford, Oxford, UK.
NIHR Oxford Biomedical Research Centre, Oxford, UK.

Eleanor Barnes (E)

Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Peter Medawar Building for Pathogen Research, Oxford, UK.
Translational Gastroenterology Unit, University of Oxford, Oxford, UK.
NIHR Oxford Biomedical Research Centre, Oxford, UK.

Susanna J Dunachie (SJ)

Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Peter Medawar Building for Pathogen Research, Oxford, UK.
Centre For Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Mahidol-Oxford Tropical Medicine Research Unit, Bangkok, Thailand, Department of Medicine, University of Oxford, Oxford, UK.

Bede Constantinides (B)

Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Hermione Webster (H)

Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Derrick Crook (D)

Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Andrew J Pollard (AJ)

NIHR Oxford Biomedical Research Centre, Oxford, UK.
Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.

Teresa Lambe (T)

Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.
Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.

Neil G Paterson (NG)

Diamond Light Source Ltd, Harwell Science & Innovation Campus, Didcot, UK.

Mark A Williams (MA)

Diamond Light Source Ltd, Harwell Science & Innovation Campus, Didcot, UK.

David R Hall (DR)

Diamond Light Source Ltd, Harwell Science & Innovation Campus, Didcot, UK.

Elizabeth E Fry (EE)

Division of Structural Biology, Nuffield Department of Medicine, University of Oxford, The Wellcome Centre for Human Genetics, Oxford, UK.

Juthathip Mongkolsapaya (J)

Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.
Siriraj Center of Research Excellence in Dengue & Emerging Pathogens, Dean Office for Research, Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand.

Jingshan Ren (J)

Division of Structural Biology, Nuffield Department of Medicine, University of Oxford, The Wellcome Centre for Human Genetics, Oxford, UK.

Gideon Schreiber (G)

Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.

David I Stuart (DI)

Division of Structural Biology, Nuffield Department of Medicine, University of Oxford, The Wellcome Centre for Human Genetics, Oxford, UK.
Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.
Diamond Light Source Ltd, Harwell Science & Innovation Campus, Didcot, UK.
Instruct-ERIC, Oxford House, Parkway Court, John Smith Drive, Oxford, UK.

Gavin R Screaton (GR)

Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.

Classifications MeSH