Effect of a Low Dose of Carvedilol on Cyclophosphamide-Induced Urinary Toxicity in Rats-A Comparison with Mesna.
carvedilol
cyclophosphamide
kidney
oxidative stress
toxicity
urinary bladder
Journal
Pharmaceuticals (Basel, Switzerland)
ISSN: 1424-8247
Titre abrégé: Pharmaceuticals (Basel)
Pays: Switzerland
ID NLM: 101238453
Informations de publication
Date de publication:
29 Nov 2021
29 Nov 2021
Historique:
received:
30
10
2021
revised:
21
11
2021
accepted:
25
11
2021
entrez:
28
12
2021
pubmed:
29
12
2021
medline:
29
12
2021
Statut:
epublish
Résumé
One of the major side effects of cyclophosphamide (CPX)-an alkylating anticancer drug that is still clinically used-is urotoxicity with hemorrhagic cystitis. The present study was designed to evaluate the ability of carvedilol to protect rats from cyclophosphamide-induced urotoxicity. Rats were injected intraperitoneally (
Identifiants
pubmed: 34959638
pii: ph14121237
doi: 10.3390/ph14121237
pmc: PMC8708009
pii:
doi:
Types de publication
Journal Article
Langues
eng
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