Diagnostic Yield of a Systematic Vascular Health Screening Approach in Adolescents at Schools.


Journal

The Journal of adolescent health : official publication of the Society for Adolescent Medicine
ISSN: 1879-1972
Titre abrégé: J Adolesc Health
Pays: United States
ID NLM: 9102136

Informations de publication

Date de publication:
01 2022
Historique:
received: 04 05 2021
revised: 27 09 2021
accepted: 15 10 2021
entrez: 21 12 2021
pubmed: 22 12 2021
medline: 1 3 2022
Statut: ppublish

Résumé

A significant proportion of noncommunicable diseases in adults has its roots in adolescence, and this is particularly true for cardiovascular disease and stroke. Detection of vascular and metabolic risk factors at young ages may aid disease prevention. In 2,088 adolescents sampled from the general population of Tyrol, Austria, and South Tyrol, Italy, we systematically assessed the frequency of yet unknown vascular and metabolic risk conditions that require further diagnostic workup or intervention (lifestyle counselling or pharmacotherapy). The health screening included medical history taking, fasting blood analysis, and blood pressure and body measurements and was performed at schools. To recruit a representative sample of adolescents, equal proportions (about 67%) of schools were invited per school type and region. Adolescents were on average 16.4 (standard deviation 1.1) years old, and 56.4% were female. A proportion of 22.8% (95% confidence interval [CI], 19.6-26.3) had previous or current physician-confirmed diseases. The health screening newly detected relevant medical conditions in 45.4% [95% CI, 41.5-49.4] (55.8% [95% CI, 52.7-58.7] in boys and 37.4% [95% CI, 35.0-39.8] in girls, p < .001). The most prevalent were elevated blood pressure and hypertension, metabolic syndrome, hypercholesterolemia, hypertriglyceridemia, hyperuricemia, and subclinical hypothyroidism. Detection of risk conditions did not depend on socioeconomic status but increased with age and body mass index. Vascular health screening in adolescents at schools has a high diagnostic yield and may aid guideline-recommended prevention in the youth. Implementation should carefully consider national differences in healthcare systems, resources, and existing programs.

Identifiants

pubmed: 34930573
pii: S1054-139X(21)00548-6
doi: 10.1016/j.jadohealth.2021.10.019
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

70-76

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2021 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

Auteurs

Sophia J Kiechl (SJ)

Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria; VASCage, Research Centre on Vascular Ageing and Stroke, Innsbruck, Austria.

Anna Staudt (A)

Department of Pediatrics II, Medical University of Innsbruck, Innsbruck, Austria.

Katharina Stock (K)

Department of Pediatrics II, Medical University of Innsbruck, Innsbruck, Austria; Department of Pediatrics III, Medical University of Innsbruck, Innsbruck, Austria.

Nina Gande (N)

Department of Pediatrics II, Medical University of Innsbruck, Innsbruck, Austria.

Benoît Bernar (B)

Department of Pediatrics II, Medical University of Innsbruck, Innsbruck, Austria; Department of Pediatrics I, Medical University of Innsbruck, Innsbruck, Austria.

Christoph Hochmayr (C)

Department of Pediatrics II, Medical University of Innsbruck, Innsbruck, Austria.

Bernhard Winder (B)

VASCage, Research Centre on Vascular Ageing and Stroke, Innsbruck, Austria; Department of Pediatrics II, Medical University of Innsbruck, Innsbruck, Austria.

Ralf Geiger (R)

Department of Pediatrics III, Medical University of Innsbruck, Innsbruck, Austria.

Andrea Griesmacher (A)

The Central Institute of Clinical Chemistry and Laboratory Medicine (ZIMCL), Medical University of Innsbruck, Innsbruck, Austria.

Alexander E Egger (AE)

The Central Institute of Clinical Chemistry and Laboratory Medicine (ZIMCL), Medical University of Innsbruck, Innsbruck, Austria.

Raimund Pechlaner (R)

Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria.

Stefan Kiechl (S)

Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria; VASCage, Research Centre on Vascular Ageing and Stroke, Innsbruck, Austria.

Michael Knoflach (M)

Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria.

Ursula Kiechl-Kohlendorfer (U)

Department of Pediatrics II, Medical University of Innsbruck, Innsbruck, Austria. Electronic address: ursula.kohlendorfer@i-med.ac.at.

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Classifications MeSH