Prospective evaluation of placental abruption in nulliparous women.
Placental abruption
adverse pregnancy outcomes
neonatal outcomes
perinatal morbidity
Journal
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
ISSN: 1476-4954
Titre abrégé: J Matern Fetal Neonatal Med
Pays: England
ID NLM: 101136916
Informations de publication
Date de publication:
Dec 2022
Dec 2022
Historique:
pubmed:
25
11
2021
medline:
24
11
2022
entrez:
24
11
2021
Statut:
ppublish
Résumé
Because most data on placental abruption are derived from retrospective studies, multiple sources of bias may have affected the results. Thus, we aimed to characterize risk factors and outcomes for placental abruption in a large prospective cohort of nulliparous women. This was a secondary analysis of women enrolled in the Nulliparous Pregnancy Outcomes Study Monitoring-to-be (nuMom2b) study, a prospective observational cohort. Participants were recruited in their first trimester of pregnancy from 8 sites and had 4 study visits, including at delivery. Placental abruption was defined by confirmed clinical criteria. The primary analysis was restricted to abruption identified antepartum and intrapartum. As a secondary analysis, we examined antepartum and intrapartum abruptions separately. We compared risk factors (maternal demographic and clinical characteristics) and outcomes in women with and without placental abruption using univariable and multivariable analyses as appropriate. 9450 women were included in the primary analysis. Abruption was identified in 0.66% ( Abruption was identified in <1% of nulliparous women. However, few maternal risk factors were identified. Neonatal morbidities were associated with an abruption and were primarily driven by gestational age due to preterm birth.
Identifiants
pubmed: 34814777
doi: 10.1080/14767058.2021.1989405
pmc: PMC9678005
mid: NIHMS1813955
doi:
Types de publication
Observational Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
8603-8610Subventions
Organisme : NICHD NIH HHS
ID : U10 HD063020
Pays : United States
Organisme : NICHD NIH HHS
ID : U10 HD063037
Pays : United States
Organisme : NICHD NIH HHS
ID : U10 HD063053
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001863
Pays : United States
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