Surgical Safety Checklist Use and Post-Caesarean Sepsis in the Lake Zone of Tanzania: Results from Safe Surgery 2020.


Journal

World journal of surgery
ISSN: 1432-2323
Titre abrégé: World J Surg
Pays: United States
ID NLM: 7704052

Informations de publication

Date de publication:
02 2022
Historique:
accepted: 21 09 2021
pubmed: 21 11 2021
medline: 1 2 2022
entrez: 20 11 2021
Statut: ppublish

Résumé

Maternal sepsis accounts for significant morbidity and mortality in lower income countries, and caesarean delivery, while often necessary, augments the risk of maternal sepsis. The aim of this study was to investigate the effect of Safe Surgery 2020 surgical safety checklist (SSC) implementation on post-caesarean sepsis in Tanzania. We conducted a study in 20 facilities in Tanzania's Lake Zone as part of the Safe Surgery 2020 intervention. We prospectively collected data on SSC adherence and maternal sepsis outcomes from 1341 caesarian deliveries. The primary outcome measure was maternal sepsis rate. The primary predictor was SSC adherence. Multivariable logistic regression was used to estimate independent associations between SSC adherence and maternal sepsis. Higher SSC adherence was associated with lower rates of maternal sepsis (<25% adherence: 5.0%; >75% adherence: 0.7%). Wound class and facility type were significantly associated with development of maternal sepsis (Wound class: Clean-Contaminated 3.7%, Contaminated/Dirty 20%, P = 0.018) (Facility Type: Health Centre 5.9%, District Hospital 4.5%, Regional Referral Hospital 1.7%, P = 0.018). In multivariable analysis, after controlling for wound class and facility type, higher SSC adherence was associated with lower rates of maternal sepsis, with an adjusted odds ratio of 0.17 per percentage point increase in SSC adherence (95% CI: 0.04, 0.79; P = 0.024). Adherence to the SSC may reduce maternal morbidity during caesarean delivery, reinforcing the assumption that surgical quality interventions improve maternal outcomes. Future studies should continue to explore additional synergies between surgical and maternal quality improvement.

Sections du résumé

BACKGROUND
Maternal sepsis accounts for significant morbidity and mortality in lower income countries, and caesarean delivery, while often necessary, augments the risk of maternal sepsis. The aim of this study was to investigate the effect of Safe Surgery 2020 surgical safety checklist (SSC) implementation on post-caesarean sepsis in Tanzania.
METHODS
We conducted a study in 20 facilities in Tanzania's Lake Zone as part of the Safe Surgery 2020 intervention. We prospectively collected data on SSC adherence and maternal sepsis outcomes from 1341 caesarian deliveries. The primary outcome measure was maternal sepsis rate. The primary predictor was SSC adherence. Multivariable logistic regression was used to estimate independent associations between SSC adherence and maternal sepsis.
RESULTS
Higher SSC adherence was associated with lower rates of maternal sepsis (<25% adherence: 5.0%; >75% adherence: 0.7%). Wound class and facility type were significantly associated with development of maternal sepsis (Wound class: Clean-Contaminated 3.7%, Contaminated/Dirty 20%, P = 0.018) (Facility Type: Health Centre 5.9%, District Hospital 4.5%, Regional Referral Hospital 1.7%, P = 0.018). In multivariable analysis, after controlling for wound class and facility type, higher SSC adherence was associated with lower rates of maternal sepsis, with an adjusted odds ratio of 0.17 per percentage point increase in SSC adherence (95% CI: 0.04, 0.79; P = 0.024).
CONCLUSIONS
Adherence to the SSC may reduce maternal morbidity during caesarean delivery, reinforcing the assumption that surgical quality interventions improve maternal outcomes. Future studies should continue to explore additional synergies between surgical and maternal quality improvement.

Identifiants

pubmed: 34799791
doi: 10.1007/s00268-021-06338-3
pii: 10.1007/s00268-021-06338-3
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

303-309

Informations de copyright

© 2021. Société Internationale de Chirurgie.

Références

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Auteurs

Taylor Wurdeman (T)

Program in Global Surgery and Social Change, Harvard Medical School, Boston, MA, USA. Taylor.wurdeman@gmail.com.
Department of Surgery, Loma Linda University Medical Center, 1884 Gould Street, Loma Linda, CA, 92354, USA. Taylor.wurdeman@gmail.com.

Steven J Staffa (SJ)

Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.

David Barash (D)

GE Foundation, Boston, MA, USA.

Ladislaus Buberwa (L)

St. Josephs Hospital, Kagondo, Kagera, Tanzania.

Eliudi Eliakimu (E)

Gender, Elderly and Children, Ministry of Health, Community Development, Dodoma, Tanzania.

Erastus Maina (E)

D-Implement, Dalberg Advisors, Nairobi, Kenya.

Sarah Maongezi (S)

Gender, Elderly and Children, Ministry of Health, Community Development, Dodoma, Tanzania.

John G Meara (JG)

Program in Global Surgery and Social Change, Harvard Medical School, Boston, MA, USA.
Department of Plastic and Oral Surgery, Boston Children's Hospital, Boston, MA, USA.

William Munyonyela (W)

Nyamiaga Hospital, Ngara, Kagera, Tanzania.

Rahma Mushi (R)

Department of Obstetrics and Gynecology, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.

Cheri Reynolds (C)

Assist International, Ripon, USA.

Christopher Strader (C)

Program in Global Surgery and Social Change, Harvard Medical School, Boston, MA, USA.
Department of Surgery, University of Massachusetts Medical School, Worcester, MA, USA.

John Varallo (J)

JHPIEGO, Baltimore, MD, USA.

Leonard Washington (L)

Department of Surgery, Bugando Medical Centre, Mwanza, Tanzania.

David Zurakowski (D)

Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.

Shehnaz Alidina (S)

Program in Global Surgery and Social Change, Harvard Medical School, Boston, MA, USA.

Ntuli A Kapologwe (NA)

President's Office, Regional Administration and Local Government, Dodoma, Tanzania.

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