Plasmids of Clostridioides difficile.
Journal
Current opinion in microbiology
ISSN: 1879-0364
Titre abrégé: Curr Opin Microbiol
Pays: England
ID NLM: 9815056
Informations de publication
Date de publication:
02 2022
02 2022
Historique:
received:
27
08
2021
revised:
20
10
2021
accepted:
23
10
2021
pubmed:
15
11
2021
medline:
26
4
2022
entrez:
14
11
2021
Statut:
ppublish
Résumé
Plasmids are ubiquitous in the bacterial world. In many microorganisms, plasmids have been implicated in important aspects of bacterial physiology and contribute to horizontal gene transfer. In contrast, knowledge on plasmids of the enteropathogen Clostridioides difficile is limited, and there appears to be no phenotypic consequence to carriage of many of the identified plasmids. Emerging evidence suggests, however, that plasmids are common in C. difficile and may encode functions relevant to pathogenesis, such as antimicrobial resistance and toxin production. Here, we review our current knowledge about the abundance, functions and clinical relevance of plasmids in C. difficile.
Identifiants
pubmed: 34775173
pii: S1369-5274(21)00152-1
doi: 10.1016/j.mib.2021.10.016
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
87-94Informations de copyright
Copyright © 2021 The Author(s). Published by Elsevier Ltd.. All rights reserved.