A rare and reversible cause of third-degree atrioventricular block: a case report.

Borreliosis Cardiac pacing Case report Lyme carditis Lyme disease Third-degree atrioventricular block

Journal

European heart journal. Case reports
ISSN: 2514-2119
Titre abrégé: Eur Heart J Case Rep
Pays: England
ID NLM: 101730741

Informations de publication

Date de publication:
Oct 2021
Historique:
received: 14 01 2021
revised: 02 03 2021
accepted: 14 09 2021
entrez: 5 11 2021
pubmed: 6 11 2021
medline: 6 11 2021
Statut: epublish

Résumé

Cardiac involvement of Lyme disease (LD) typically results in atrioventricular (AV) conduction disturbance, mainly third-degree AV block. A 54-year-old patient presented to our emergency department due to recurrent syncope. Third-degree AV block with a ventricular escape rhythm (33 b.p.m.) was identified as the underlying rhythm. Transthoracic echocardiography (TTE) was normal. To rule out common reversible causes of complete AV block, a screening test for Lyme borreliosis was carried out. Elevated levels for borrelia IgG/IgM were found and confirmed by western blot analysis. Lyme carditis (LC) was postulated as the most likely cause of the third-degree AV block given the young age of the patient. Initiation of antibiotic therapy with ceftriaxone resulted in a gradual normalization of the AV conduction with stable first-degree AV block on Day 6 of therapy. The patient was changed on oral antibiotics (doxycycline) and discharged without a pacemaker. After 3 months, the AV conduction recovered to normal. Lyme carditis should always be considered, particularly in younger patients with new-onset AV block and without evidence of structural heart disease. Atrioventricular block recovers in the majority of cases after appropriate antibiotic treatment.

Sections du résumé

BACKGROUND BACKGROUND
Cardiac involvement of Lyme disease (LD) typically results in atrioventricular (AV) conduction disturbance, mainly third-degree AV block.
CASE SUMMARY METHODS
A 54-year-old patient presented to our emergency department due to recurrent syncope. Third-degree AV block with a ventricular escape rhythm (33 b.p.m.) was identified as the underlying rhythm. Transthoracic echocardiography (TTE) was normal. To rule out common reversible causes of complete AV block, a screening test for Lyme borreliosis was carried out. Elevated levels for borrelia IgG/IgM were found and confirmed by western blot analysis. Lyme carditis (LC) was postulated as the most likely cause of the third-degree AV block given the young age of the patient. Initiation of antibiotic therapy with ceftriaxone resulted in a gradual normalization of the AV conduction with stable first-degree AV block on Day 6 of therapy. The patient was changed on oral antibiotics (doxycycline) and discharged without a pacemaker. After 3 months, the AV conduction recovered to normal.
DISCUSSION CONCLUSIONS
Lyme carditis should always be considered, particularly in younger patients with new-onset AV block and without evidence of structural heart disease. Atrioventricular block recovers in the majority of cases after appropriate antibiotic treatment.

Identifiants

pubmed: 34738056
doi: 10.1093/ehjcr/ytab372
pii: ytab372
pmc: PMC8564693
doi:

Types de publication

Case Reports

Langues

eng

Pagination

ytab372

Informations de copyright

© The Author(s) 2021. Published by Oxford University Press on behalf of the European Society of Cardiology.

Références

Clin Infect Dis. 2006 Nov 1;43(9):1089-134
pubmed: 17029130
Infect Dis Clin North Am. 2008 Jun;22(2):275-88, vi
pubmed: 18452801
Clin Cardiol. 2018 Dec;41(12):1611-1616
pubmed: 30350436
Clin Infect Dis. 2014 Oct;59(7):996-1000
pubmed: 24879781
J Am Coll Cardiol. 2019 Feb 19;73(6):717-726
pubmed: 30765038

Auteurs

Gino Lee (G)

Department of Cardiology, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland.

Patrick Badertscher (P)

Department of Cardiology, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland.

Christian Sticherling (C)

Department of Cardiology, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland.

Stefan Osswald (S)

Department of Cardiology, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland.

Classifications MeSH