Effects of the atrium on intraventricular flow patterns during mechanical circulatory support.
Left ventricle assist device
computational fluid dynamics
intraventricular flow pattern
left atrium
residence time
shear stress history
Journal
The International journal of artificial organs
ISSN: 1724-6040
Titre abrégé: Int J Artif Organs
Pays: United States
ID NLM: 7802649
Informations de publication
Date de publication:
Apr 2022
Apr 2022
Historique:
pubmed:
31
10
2021
medline:
15
3
2022
entrez:
30
10
2021
Statut:
ppublish
Résumé
Simulations of the ventricular flow patterns during left ventricular assist device (LVAD) support are mainly performed with idealized cylindrical inflow, neglecting the influence of the atrial vortex. In this study, the influence of the left atrium (LA) on the intra-ventricular flow was investigated via Computational Fluid Dynamics (CFD) simulations. Ventricular flow was simulated by a combined Eulerian (carrier flow)/Lagrangian (particles) approach taking into account either the LA or a cylindrical inflow section to mimic a fully support condition. The flow deviation at the mitral valve, the blood low-velocity volume as well as the residence time and shear stress history of the particles were calculated. Inclusion of the LA deflects the flow at the mitral valve by 25°, resulting in an asymmetric flow jet entering the left ventricle. This reduced the ventricular low-velocity volume by 40% (from 6.4 to 3.9 cm
Identifiants
pubmed: 34715752
doi: 10.1177/03913988211056018
pmc: PMC8922056
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
421-430Références
Biomed Eng Online. 2016 Dec 28;15(Suppl 2):136
pubmed: 28155674
Circ Heart Fail. 2018 Apr;11(4):e004325
pubmed: 29666072
Ann Biomed Eng. 2009 Mar;37(3):503-15
pubmed: 19130229
J Thorac Cardiovasc Surg. 2010 Jun;139(6):1501-10
pubmed: 20363003
ASAIO J. 2017 Jul/Aug;63(4):392-400
pubmed: 28009715
ASAIO J. 2019 Sep/Oct;65(7):698-706
pubmed: 30134259
ASAIO J. 2013 Jul-Aug;59(4):452-5
pubmed: 23820289
J Biomech Eng. 2012 Aug;134(8):081002
pubmed: 22938355
Sci Rep. 2017 Feb 20;7:42720
pubmed: 28218279
J Biomech. 2018 Apr 27;72:106-115
pubmed: 29567308
Artif Organs. 2021 Sep;45(9):1014-1023
pubmed: 33683718
J Heart Lung Transplant. 2017 Oct;36(10):1080-1086
pubmed: 28942782
Circulation. 1990 May;81(5):1488-97
pubmed: 2110034
Artif Organs. 2020 Nov;44(11):E459-E469
pubmed: 32530104
Ann N Y Acad Sci. 2004 May;1015:351-66
pubmed: 15201174
Arteriosclerosis. 1990 Jul-Aug;10(4):607-15
pubmed: 2369370
ASAIO J. 2019 Feb;65(2):152-159
pubmed: 29677037
Circulation. 1985 Jun;71(6):1105-12
pubmed: 3995706
Card Fail Rev. 2017 Apr;3(1):7-11
pubmed: 28785469
Artif Organs. 2020 Sep;44(9):939-946
pubmed: 32302423
J Biomech Eng. 2003 Dec;125(6):922-7
pubmed: 14986421
Front Cardiovasc Med. 2018 Apr 04;5:34
pubmed: 29670888
Ann Thorac Surg. 2019 Apr;107(4):1181-1186
pubmed: 30365959
Int J Artif Organs. 2021 Jan;44(1):30-38
pubmed: 32022612
J Physiol Sci. 2014 Mar;64(2):105-12
pubmed: 24385190
JACC Heart Fail. 2017 Oct;5(10):703-711
pubmed: 28958345
Cardiovasc Eng Technol. 2015 Jun;6(2):95-104
pubmed: 26577230
Ann Biomed Eng. 2020 Feb;48(2):794-804
pubmed: 31741229
J Heart Lung Transplant. 2017 May;36(5):586-588
pubmed: 28215476
J Am Coll Cardiol. 2015 Jun 16;65(23):2542-55
pubmed: 26065994
Artif Organs. 2012 May;36(5):470-8
pubmed: 22171892
Neth Heart J. 2012 Apr;20(4):167-75
pubmed: 22083426
Ann Biomed Eng. 2010 Oct;38(10):3058-69
pubmed: 20499185
ASAIO J. 2021 Jan 1;67(1):74-83
pubmed: 33346993
Comput Biol Med. 2019 Mar;106:46-53
pubmed: 30677603
Heart. 2001 Oct;86(4):448-55
pubmed: 11559688
Ann Cardiothorac Surg. 2018 Jan;7(1):3-11
pubmed: 29492379
Pathophysiol Haemost Thromb. 2003 Sep-2004 Dec;33(5-6):455-7
pubmed: 15692260
Ann Biomed Eng. 2008 Nov;36(11):1793-804
pubmed: 18787954
JACC Heart Fail. 2017 Oct;5(10):712-714
pubmed: 28958346
Magn Reson Imaging. 2018 Apr;47:83-88
pubmed: 29217489