Multiparametric MRI and Radiomics in Prostate Cancer: A Review of the Current Literature.

Gleason score PI-RADS cancer magnetic resonance imaging prostate radiomics

Journal

Diagnostics (Basel, Switzerland)
ISSN: 2075-4418
Titre abrégé: Diagnostics (Basel)
Pays: Switzerland
ID NLM: 101658402

Informations de publication

Date de publication:
03 Oct 2021
Historique:
received: 03 09 2021
revised: 26 09 2021
accepted: 27 09 2021
entrez: 23 10 2021
pubmed: 24 10 2021
medline: 24 10 2021
Statut: epublish

Résumé

Prostate cancer (PCa) represents the fourth most common cancer and the fifth leading cause of cancer death of men worldwide. Multiparametric MRI (mp-MRI) has high sensitivity and specificity in the detection of PCa, and it is currently the most widely used imaging technique for tumor localization and cancer staging. mp-MRI plays a key role in risk stratification of naïve patients, in active surveillance for low-risk patients, and in monitoring recurrence after definitive therapy. Radiomics is an emerging and promising tool which allows a quantitative tumor evaluation from radiological images via conversion of digital images into mineable high-dimensional data. The purpose of radiomics is to increase the features available to detect PCa, to avoid unnecessary biopsies, to define tumor aggressiveness, and to monitor post-treatment recurrence of PCa. The integration of radiomics data, including different imaging modalities (such as PET-CT) and other clinical and histopathological data, could improve the prediction of tumor aggressiveness as well as guide clinical decisions and patient management. The purpose of this review is to describe the current research applications of radiomics in PCa on MR images.

Identifiants

pubmed: 34679527
pii: diagnostics11101829
doi: 10.3390/diagnostics11101829
pmc: PMC8534893
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

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Auteurs

Federico Midiri (F)

Section of Radiology-BiND, University Hospital "Paolo Giaccone", 90127 Palermo, Italy.

Federica Vernuccio (F)

Section of Radiology-BiND, University Hospital "Paolo Giaccone", 90127 Palermo, Italy.

Pierpaolo Purpura (P)

Department of Radiology, Fondazione Istituto "Giuseppe Giglio", Ct.da Pietrapollastra, Via Pisciotto, Cefalù, 90015 Palermo, Italy.

Pierpaolo Alongi (P)

Nuclear Medicine Unit, Fondazione Istituto "Giuseppe Giglio", Ct.da Pietrapollastra, Via Pisciotto, Cefalù, 90015 Palermo, Italy.

Tommaso Vincenzo Bartolotta (TV)

Section of Radiology-BiND, University Hospital "Paolo Giaccone", 90127 Palermo, Italy.
Department of Radiology, Fondazione Istituto "Giuseppe Giglio", Ct.da Pietrapollastra, Via Pisciotto, Cefalù, 90015 Palermo, Italy.

Classifications MeSH