Trends of Multidrug-Resistant Pathogens, Difficult to Treat Bloodstream Infections, and Antimicrobial Consumption at a Tertiary Care Center in Lebanon from 2015-2020: COVID-19 Aftermath.

Acinetobacter baumannii and COVID-19 CRE MDR and COVID-19 VRE and COVID-19 antimicrobial resistance antimicrobial stewardship in COVID-19

Journal

Antibiotics (Basel, Switzerland)
ISSN: 2079-6382
Titre abrégé: Antibiotics (Basel)
Pays: Switzerland
ID NLM: 101637404

Informations de publication

Date de publication:
21 Aug 2021
Historique:
received: 07 07 2021
revised: 04 08 2021
accepted: 18 08 2021
entrez: 27 8 2021
pubmed: 28 8 2021
medline: 28 8 2021
Statut: epublish

Résumé

We studied the trend of antimicrobial resistance and consumption at Saint George Hospital University Medical Center (SGHUMC), a tertiary care center in Beirut, Lebanon, with a focus on the SARS-CoV-2 pandemic. We calculated the isolation density/1000 patient-days (PD) of the most isolated organisms from 1 January 2015-31 December 2020 that included: After applying exclusion criteria, we analyzed 1614 blood cultures out of 8314 cultures. We isolated 85 species, most commonly Eco, at 52%. The isolation density of total BSI in 2020 decreased by 16%: 82 patients were spared from bacteremia, with 13 being DTR. The isolation density of CRE BSI/1000 PD decreased by 64% from 2019 to 2020, while VREfm BSI decreased by 34%. There was a significant decrease of 80% in Ab isolates (

Identifiants

pubmed: 34439065
pii: antibiotics10081016
doi: 10.3390/antibiotics10081016
pmc: PMC8388970
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Amanda Chamieh (A)

Department of Infectious Diseases, Saint George Hospital University Medical Center, Beirut 11002807, Lebanon.
Institut de Recherche pour le Développement (IRD), UMR Microbes Evolution Phylogeny and Infections (MEPHI), Aix-Marseille Université, 13007 Marseille, France.
Institut Hospitalo-Universitaire Méditerranée Infection, 13005 Marseille, France.

Rita Zgheib (R)

Institut Hospitalo-Universitaire Méditerranée Infection, 13005 Marseille, France.
Institut de Recherche pour le Développement (IRD), Service de Santé des Armées, AP-HM, UMR Vecteurs Infections Tropicales et Méditerranéennes (VITROME), Aix Marseille Université, 13007 Marseille, France.

Sabah El-Sawalhi (S)

Institut de Recherche pour le Développement (IRD), UMR Microbes Evolution Phylogeny and Infections (MEPHI), Aix-Marseille Université, 13007 Marseille, France.
Institut Hospitalo-Universitaire Méditerranée Infection, 13005 Marseille, France.

Laure Yammine (L)

Department of Infectious Diseases, Saint George Hospital University Medical Center, Beirut 11002807, Lebanon.

Gerard El-Hajj (G)

Department of Medical Imaging, Saint George Hospital University Medical Center, Beirut 11002807, Lebanon.

Omar Zmerli (O)

Department of Infectious Diseases, Saint George Hospital University Medical Center, Beirut 11002807, Lebanon.

Claude Afif (C)

Department of Infectious Diseases, Saint George Hospital University Medical Center, Beirut 11002807, Lebanon.

Jean-Marc Rolain (JM)

Institut de Recherche pour le Développement (IRD), UMR Microbes Evolution Phylogeny and Infections (MEPHI), Aix-Marseille Université, 13007 Marseille, France.
Institut Hospitalo-Universitaire Méditerranée Infection, 13005 Marseille, France.

Eid Azar (E)

Department of Infectious Diseases, Saint George Hospital University Medical Center, Beirut 11002807, Lebanon.

Classifications MeSH