Scalable Reporter Assays to Analyze the Regulation of


Journal

Toxins
ISSN: 2072-6651
Titre abrégé: Toxins (Basel)
Pays: Switzerland
ID NLM: 101530765

Informations de publication

Date de publication:
29 07 2021
Historique:
received: 09 06 2021
revised: 27 07 2021
accepted: 28 07 2021
entrez: 26 8 2021
pubmed: 27 8 2021
medline: 27 1 2022
Statut: epublish

Résumé

Stx2 is the major virulence factor of EHEC and is associated with an increased risk for HUS in infected patients. The conditions influencing its expression in the intestinal tract are largely unknown. For optimal management and treatment of infected patients, the identification of environmental conditions modulating Stx2 levels in the human gut is of central importance. In this study, we established a set of chromosomal

Identifiants

pubmed: 34437405
pii: toxins13080534
doi: 10.3390/toxins13080534
pmc: PMC8402550
pii:
doi:

Substances chimiques

Shiga Toxin 2 0
Green Fluorescent Proteins 147336-22-9
Luciferases EC 1.13.12.-

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Martin B Koeppel (MB)

Max-von-Pettenkofer Institute, LMU Munich, Pettenkoferstr. 9a, 80336 Munich, Germany.
German Center for Infection Research (DZIF), Partner Site LMU Munich, 80336 Munich, Germany.

Jana Glaser (J)

Max-von-Pettenkofer Institute, LMU Munich, Pettenkoferstr. 9a, 80336 Munich, Germany.
German Center for Infection Research (DZIF), Partner Site LMU Munich, 80336 Munich, Germany.

Tobias Baumgartner (T)

Max-von-Pettenkofer Institute, LMU Munich, Pettenkoferstr. 9a, 80336 Munich, Germany.
German Center for Infection Research (DZIF), Partner Site LMU Munich, 80336 Munich, Germany.

Stefanie Spriewald (S)

Max-von-Pettenkofer Institute, LMU Munich, Pettenkoferstr. 9a, 80336 Munich, Germany.
German Center for Infection Research (DZIF), Partner Site LMU Munich, 80336 Munich, Germany.

Roman G Gerlach (RG)

Mikrobiologisches Institut-Klinische Mikrobiologie, Immunologie und Hygiene, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Wasserturmstraße 3/5, 91054 Erlangen, Germany.

Benedikt von Armansperg (B)

Max-von-Pettenkofer Institute, LMU Munich, Pettenkoferstr. 9a, 80336 Munich, Germany.
German Center for Infection Research (DZIF), Partner Site LMU Munich, 80336 Munich, Germany.

John M Leong (JM)

Department of Molecular Biology and Microbiology, Tufts University School of Medicine, 136 Harrison Ave, Boston, MA 02111, USA.

Bärbel Stecher (B)

Max-von-Pettenkofer Institute, LMU Munich, Pettenkoferstr. 9a, 80336 Munich, Germany.
German Center for Infection Research (DZIF), Partner Site LMU Munich, 80336 Munich, Germany.

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Classifications MeSH