Myocardial and Pericardial Toxicity Associated With Immune Checkpoint Inhibitors in Cancer Patients.
CTLA, cytotoxic T-lymphocyte-associated antigen
ECG, electrocardiogram
ICI, immune checkpoint inhibitors
IRAE, immunity-related adverse effects
PD, programmed cell death receptor
PDL, programmed cell death ligand
cardiotoxicity
immune checkpoint inhibitors
immunity-related adverse events
Journal
JACC. Case reports
ISSN: 2666-0849
Titre abrégé: JACC Case Rep
Pays: Netherlands
ID NLM: 101757292
Informations de publication
Date de publication:
Feb 2020
Feb 2020
Historique:
received:
01
08
2019
revised:
13
11
2019
accepted:
18
11
2019
entrez:
28
7
2021
pubmed:
19
2
2020
medline:
19
2
2020
Statut:
epublish
Résumé
We recount a single-center experience with cardiac immunity-related adverse effects in patients treated with immune checkpoint inhibitors. Of 2,830 patients, 9 patients (0.3%) developed cardiac immunity-related adverse effects (4 cases of cardiomyopathies, 2 of myocarditis, 2 of acute pericarditis, and 1 of large pericardial effusion). Disease profiles, hospital courses, and outcomes are reported. (
Identifiants
pubmed: 34317203
doi: 10.1016/j.jaccas.2019.11.080
pii: S2666-0849(19)30691-6
pmc: PMC8298653
doi:
Types de publication
Case Reports
Langues
eng
Pagination
191-199Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2020 The Authors.
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