Nanotechnology as a Shield against COVID-19: Current Advancement and Limitations.


Journal

Viruses
ISSN: 1999-4915
Titre abrégé: Viruses
Pays: Switzerland
ID NLM: 101509722

Informations de publication

Date de publication:
24 06 2021
Historique:
received: 01 06 2021
revised: 21 06 2021
accepted: 21 06 2021
entrez: 2 7 2021
pubmed: 3 7 2021
medline: 16 7 2021
Statut: epublish

Résumé

The coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a global health problem that the WHO declared a pandemic. COVID-19 has resulted in a worldwide lockdown and threatened to topple the global economy. The mortality of COVID-19 is comparatively low compared with previous SARS outbreaks, but the rate of spread of the disease and its morbidity is alarming. This virus can be transmitted human-to-human through droplets and close contact, and people of all ages are susceptible to this virus. With the advancements in nanotechnology, their remarkable properties, including their ability to amplify signal, can be used for the development of nanobiosensors and nanoimaging techniques that can be used for early-stage detection along with other diagnostic tools. Nano-based protection equipment and disinfecting agents can provide much-needed protection against SARS-CoV-2. Moreover, nanoparticles can serve as a carrier for antigens or as an adjuvant, thereby making way for the development of a new generation of vaccines. The present review elaborates the role of nanotechnology-based tactics used for the detection, diagnosis, protection, and treatment of COVID-19 caused by the SARS-CoV-2 virus.

Identifiants

pubmed: 34202815
pii: v13071224
doi: 10.3390/v13071224
pmc: PMC8310263
pii:
doi:

Substances chimiques

Antiviral Agents 0
COVID-19 Vaccines 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Mahendra Rai (M)

Nanobiotechnology Lab., Department of Biotechnology, Sant Gadge Baba Amravati University, Amravati 444 602, Maharashtra, India.

Shital Bonde (S)

Nanobiotechnology Lab., Department of Biotechnology, Sant Gadge Baba Amravati University, Amravati 444 602, Maharashtra, India.

Alka Yadav (A)

Nanobiotechnology Lab., Department of Biotechnology, Sant Gadge Baba Amravati University, Amravati 444 602, Maharashtra, India.

Arpita Bhowmik (A)

Faculty of Medicine, Dentistry and Health, The University of Sheffield, Sheffield S10 2TN, UK.

Sanjay Rathod (S)

Department of Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA.

Pramod Ingle (P)

Nanobiotechnology Lab., Department of Biotechnology, Sant Gadge Baba Amravati University, Amravati 444 602, Maharashtra, India.

Aniket Gade (A)

Nanobiotechnology Lab., Department of Biotechnology, Sant Gadge Baba Amravati University, Amravati 444 602, Maharashtra, India.

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Classifications MeSH