Different Attitudes of Patients and Psychiatrists Toward Benzodiazepine Treatment.

anxiolytics belief benzodiazepine receptor agonist dependence hypnotics

Journal

Neuropsychiatric disease and treatment
ISSN: 1176-6328
Titre abrégé: Neuropsychiatr Dis Treat
Pays: New Zealand
ID NLM: 101240304

Informations de publication

Date de publication:
2021
Historique:
received: 06 04 2021
accepted: 27 05 2021
entrez: 24 6 2021
pubmed: 25 6 2021
medline: 25 6 2021
Statut: epublish

Résumé

Concern regarding the benefit/risk ratio of the long-term use of benzodiazepines (BDZs) and Z-drugs is increasing. To prevent the risk of dependence in BDZ long-term use, it is essential to understand the attitudes of patients and psychiatrists toward BDZ treatment. The aims of this investigation were to 1) obtain information on patients' attitudes with long-term BDZ use and their referring psychiatrists' attitudes toward BDZ treatment, including their perception of the difficulty of reducing the dose of BDZs, and 2) identify discrepancies between patients' and psychiatrists' perceptions. A brief questionnaire was constructed to investigate the attitudes of patients receiving BDZ treatment and their referring psychiatrists. Our sample comprised 155 patients who received BDZ treatment for more than one year and their referring eight psychiatrists. Both the patients and their psychiatrists completed our questionnaire between August 2017 and December 2017. Of the patients, 13% felt that it was more difficult to reduce the dose of BDZs than their referring psychiatrists (type A discrepancy), while 25% felt that it was less difficult (type B discrepancy). In the multivariate logistic regression analysis, the female sex and both the patients' ("psychotherapy plus BDZs was necessary" and "it was necessary to increase the dose of BDZs") and psychiatrists' beliefs ("short-term prescription was justified") were associated with type A discrepancies. Type B discrepancies were associated with psychiatrists' beliefs that the patient's wishes justified the use of BDZs and that the cessation of treatment with BDZs would lead to the deterioration of their rapport with their patients. To overcome the discrepancies in the attitudes of patients and psychiatrists toward the cessation of BDZ treatment, it is necessary to promote patient-centered care involving patient psychoeducation and practice guidelines for the decision-making process. Further studies investigating the promotion of patient-centered care to reduce BDZ use are needed.

Sections du résumé

BACKGROUND BACKGROUND
Concern regarding the benefit/risk ratio of the long-term use of benzodiazepines (BDZs) and Z-drugs is increasing. To prevent the risk of dependence in BDZ long-term use, it is essential to understand the attitudes of patients and psychiatrists toward BDZ treatment. The aims of this investigation were to 1) obtain information on patients' attitudes with long-term BDZ use and their referring psychiatrists' attitudes toward BDZ treatment, including their perception of the difficulty of reducing the dose of BDZs, and 2) identify discrepancies between patients' and psychiatrists' perceptions.
METHODS METHODS
A brief questionnaire was constructed to investigate the attitudes of patients receiving BDZ treatment and their referring psychiatrists. Our sample comprised 155 patients who received BDZ treatment for more than one year and their referring eight psychiatrists. Both the patients and their psychiatrists completed our questionnaire between August 2017 and December 2017.
RESULTS RESULTS
Of the patients, 13% felt that it was more difficult to reduce the dose of BDZs than their referring psychiatrists (type A discrepancy), while 25% felt that it was less difficult (type B discrepancy). In the multivariate logistic regression analysis, the female sex and both the patients' ("psychotherapy plus BDZs was necessary" and "it was necessary to increase the dose of BDZs") and psychiatrists' beliefs ("short-term prescription was justified") were associated with type A discrepancies. Type B discrepancies were associated with psychiatrists' beliefs that the patient's wishes justified the use of BDZs and that the cessation of treatment with BDZs would lead to the deterioration of their rapport with their patients.
CONCLUSION CONCLUSIONS
To overcome the discrepancies in the attitudes of patients and psychiatrists toward the cessation of BDZ treatment, it is necessary to promote patient-centered care involving patient psychoeducation and practice guidelines for the decision-making process. Further studies investigating the promotion of patient-centered care to reduce BDZ use are needed.

Identifiants

pubmed: 34163166
doi: 10.2147/NDT.S314440
pii: 314440
pmc: PMC8214561
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1927-1936

Informations de copyright

© 2021 Kawamata et al.

Déclaration de conflit d'intérêts

Norio Yasui-Furukori reports personal fees from Mochida, Otsuka Pharmaceuticals, Dainippon-Sumitomo, and MSD, outside the submitted work. The remaining authors declare that they have no competing interests to report.

Références

Can Fam Physician. 2010 Nov;56(11):e398-406
pubmed: 21075981
Cochrane Database Syst Rev. 2019 Jun 03;6:CD001026
pubmed: 31158298
Lancet. 1998 Oct 24;352(9137):1331-6
pubmed: 9802269
J Am Geriatr Soc. 2008 Dec;56(12):2285-91
pubmed: 19093928
Int J Psychiatry Clin Pract. 2017 Sep;21(3):166-176
pubmed: 28367707
BMJ Open. 2019 Jul 26;9(7):e029641
pubmed: 31350250
Int Rev Psychiatry. 2005 Jun;17(3):189-97
pubmed: 16194790
J Toxicol Clin Toxicol. 2002;40(1):69-75
pubmed: 11990206
BMC Psychiatry. 2015 May 13;15:116
pubmed: 25968120
Int Clin Psychopharmacol. 2019 Nov;34(6):291-297
pubmed: 30998597
J Anxiety Disord. 2009 May;23(4):477-81
pubmed: 19010641
Patient Prefer Adherence. 2020 Jun 17;14:995-1010
pubmed: 32606616
J Psychopharmacol. 2014 May;28(5):403-39
pubmed: 24713617
Gen Hosp Psychiatry. 2020 Jan - Feb;62:49-55
pubmed: 31786448
Psychopharmacology (Berl). 2003 May;167(3):297-303
pubmed: 12669174
Am J Public Health. 1994 Feb;84(2):242-6
pubmed: 8296948
Drug Saf. 2011 Feb 1;34(2):125-56
pubmed: 21247221
Cochrane Database Syst Rev. 2019 Mar 28;3:CD010677
pubmed: 30921478
Scand J Prim Health Care. 1996 Jun;14(2):106-10
pubmed: 8792504
N Engl J Med. 2017 Mar 23;376(12):1147-1157
pubmed: 28328330
J Clin Med. 2019 Dec 04;8(12):
pubmed: 31817181
BMC Fam Pract. 2019 Jan 5;20(1):4
pubmed: 30611211
J Psychopharmacol. 2015 May;29(5):459-525
pubmed: 25969470
Accid Anal Prev. 2013 Nov;60:254-67
pubmed: 22785089
Aust Fam Physician. 2016 Jul;45(7):506-11
pubmed: 27610435
Cochrane Database Syst Rev. 2009 Jan 21;(1):CD005335
pubmed: 19160253
Fam Pract. 2013 Aug;30(4):404-10
pubmed: 23515374
BMC Psychiatry. 2014;14 Suppl 1:S1
pubmed: 25081580
Psychiatry Clin Neurosci. 2015 Aug;69(8):440-7
pubmed: 25601291

Auteurs

Yasushi Kawamata (Y)

Department of Psychiatry, Dokkyo Medical University School of Medicine, Mibu, Japan.

Norio Sugawara (N)

Department of Psychiatry, Dokkyo Medical University School of Medicine, Mibu, Japan.
Department of Neuropsychiatry, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.

Masamichi Ishioka (M)

Department of Psychiatry, Minato Hospital, Hachinohe, Japan.

Kazutoshi Kubo (K)

Department of Neuropsychiatry, Hirosaki-Aiseikai Hospital, Hirosaki, Japan.

Katsuji Suzuki (K)

Department of Psychiatry, Aomori Central Hospital, Aomori, Japan.

Akira Fujii (A)

Department of Neuropsychiatry, Mutsu General Hospital, Mutsu, Japan.

Hanako Furukori (H)

Department of Neuropsychiatry, Kuroishi-Akebono Hospital, Kuroishi, Japan.

Taku Nakagami (T)

Department of Psychiatry, Nakagami Mental Clinic, Ohdate, Japan.

Norio Yasui-Furukori (N)

Department of Psychiatry, Dokkyo Medical University School of Medicine, Mibu, Japan.
Department of Neuropsychiatry, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.

Kazutaka Shimoda (K)

Department of Psychiatry, Dokkyo Medical University School of Medicine, Mibu, Japan.

Classifications MeSH