Spatial distribution of diabetic capillary non-perfusion.
capillary non-perfusion
deep capillary plexus
diabetic retinopathy
optical coherence tomography angiography
superficial capillary plexus
Journal
Microcirculation (New York, N.Y. : 1994)
ISSN: 1549-8719
Titre abrégé: Microcirculation
Pays: United States
ID NLM: 9434935
Informations de publication
Date de publication:
10 2021
10 2021
Historique:
received:
07
02
2021
accepted:
02
06
2021
pubmed:
10
6
2021
medline:
25
3
2022
entrez:
9
6
2021
Statut:
ppublish
Résumé
To evaluate the distribution of capillary non-perfusion (CNP) in superficial and deep capillary plexuses (SCP and DCP) in eyes with diabetic retinopathy (DR). In this retrospective case series, macular optical coherence tomography angiography (OCTA) images were obtained from eyes with DR without diabetic macular edema (DME). The area of CNP in SCP and DCP was delineated using an automated approach after excluding the foveal avascular zone (FAZ) and major retinal vessels. The distribution and spatial correlation of the CNP in each layer were analyzed. Forty-three eyes of 27 patients with DR with a mean age of 59.10 ± 9.05 years were included. The mean CNP area in SCP was statistically significantly higher than DCP (0.722 ± 0.437 mm In DR, SCP is more ischemic than DCP. This is in contrast to the previously described oxygenation-dependent ischemic cascade following acute retinal vascular occlusions. This study provides further insight into the retinal ischemia in DR.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e12719Informations de copyright
© 2021 John Wiley & Sons Ltd.
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