Predictive values of early head computed tomography for survival outcome after cardiac arrest in childhood: a pilot study.

Adolescent Brain / diagnostic imaging Brain Injuries / diagnostic imaging Child Child, Preschool Disease-Free Survival Female Head / diagnostic imaging Humans Infant Infant, Newborn Male Neuroimaging Out-of-Hospital Cardiac Arrest / diagnostic imaging Pilot Projects Retrospective Studies Survival Rate Tomography, X-Ray Computed

Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
08 06 2021
Historique:
received: 04 02 2021
accepted: 28 05 2021
entrez: 9 6 2021
pubmed: 10 6 2021
medline: 21 10 2021
Statut: epublish

Résumé

Predicting outcomes of children after cardiac arrest (CA) remains challenging. To identify useful prognostic markers for pediatric CA, we retrospectively analyzed the early findings of head computed tomography (CT) of patients. Subjects were non-traumatic, out-of-hospital CA patients < 16 years of age who underwent the first head CT within 24 h in our institute from 2006 to 2018 (n = 70, median age: 4 months, range 0-163). Of the 24 patients with return of spontaneous circulation, 14 survived up to 30 days after CA. The degree of brain damage was quantitatively measured with modified methods of the Alberta Stroke Program Early CT Score (mASPECTS) and simplified gray-matter-attenuation-to-white-matter-attenuation ratio (sGWR). The 14 survivors showed higher mASPECTS values than the 56 non-survivors (p = 0.035). All 3 patients with mASPECTS scores ≥ 20 survived, while an sGWR ≥ 1.14 indicated a higher chance of survival than an sGWR < 1.14 (54.5% vs. 13.6%). Follow-up magnetic resonance imaging for survivors validated the correlation of the mASPECTS < 15 with severe brain damage. Thus, low mASPECTS scores were associated with unfavorable neurological outcomes on the Pediatric Cerebral Performance Category scale. A quantitative analysis of early head CT findings might provide clues for predicting survival of pediatric CA.

Identifiants

DOI: 10.1038/s41598-021-91628-y PMID: 34103642 PMC: PMC8187472
pubmed: 34103642
doi: 10.1038/s41598-021-91628-y
pii: 10.1038/s41598-021-91628-y
pmc: PMC8187472
doi:

Types de publication

Clinical Trial Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

12090

Références

Front Neurol. 2012 Jul 31;3:122
pubmed: 23015799
Resuscitation. 2018 Nov;132:21-28
pubmed: 30165096
Radiographics. 2008 Mar-Apr;28(2):417-39; quiz 617
pubmed: 18349449
J Pediatr. 1992 Jul;121(1):68-74
pubmed: 1625096
Resuscitation. 2014 Oct;85(10):1348-53
pubmed: 24892267
Resuscitation. 2019 Dec;145:8-14
pubmed: 31585185
Intensive Care Med. 2013 Jul;39(7):1306-12
pubmed: 23632740
Pediatrics. 2020 Jan;145(1):
pubmed: 31727859
Crit Care. 2018 Nov 22;22(1):323
pubmed: 30466477
Circ J. 2017 Oct 25;81(11):1628-1635
pubmed: 28592725
Pediatr Crit Care Med. 2015 Jul;16(6):542-8
pubmed: 25844694
Pediatrics. 2011 Jun;127(6):e1550-7
pubmed: 21576305
Sci Rep. 2019 May 7;9(1):7032
pubmed: 31065052
Scand J Trauma Resusc Emerg Med. 2013 Jul 19;21:57
pubmed: 23870424
Resuscitation. 2019 Apr;137:7-13
pubmed: 30735742
Circulation. 2012 Sep 11;126(11):1363-72
pubmed: 22887927
Pediatr Neurol. 2016 Nov;64:44-51
pubmed: 27663488
Front Pediatr. 2019 Jun 04;7:223
pubmed: 31214555
Data Brief. 2019 Nov 04;27:104755
pubmed: 31763408
AJNR Am J Neuroradiol. 2019 Jan;40(1):33-38
pubmed: 30498017
Circulation. 2019 Aug 6;140(6):e194-e233
pubmed: 31242751
Neurology. 2020 Mar 24;94(12):e1259-e1270
pubmed: 32075895
Cereb Cortex. 2001 Apr;11(4):335-42
pubmed: 11278196
Neuroradiology. 2018 Sep;60(9):889-901
pubmed: 30066278
Circulation. 1991 Aug;84(2):960-75
pubmed: 1860248
Resuscitation. 2018 Aug;129:114-120
pubmed: 29679698
Radiology. 2020 Mar;294(3):638-644
pubmed: 31990267
Resuscitation. 2012 Jul;83(7):848-54
pubmed: 22227499
Clin Neuroradiol. 2015 Mar;25(1):49-54
pubmed: 24626778
Bone Marrow Transplant. 2013 Mar;48(3):452-8
pubmed: 23208313
Resuscitation. 2015 Oct;95:202-22
pubmed: 26477702
Resuscitation. 2015 Nov;96:46-52
pubmed: 26232516
Scand J Trauma Resusc Emerg Med. 2013 Apr 08;21:23
pubmed: 23566292
Resuscitation. 2019 Jul;140:161-169
pubmed: 30953628
Neuroradiology. 2004 Sep;46(9):781-6
pubmed: 15243725
J Clin Med. 2020 Mar 10;9(3):
pubmed: 32164225
Circulation. 2009 Mar 24;119(11):1484-91
pubmed: 19273724

Auteurs

Kenichi Tetsuhara (K)

Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Emergency and Critical Care Center, Kyushu University Hospital, Fukuoka, Japan.

Noriyuki Kaku (N)

Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. kakunori@pediatr.med.kyushu-u.ac.jp.
Emergency and Critical Care Center, Kyushu University Hospital, Fukuoka, Japan. kakunori@pediatr.med.kyushu-u.ac.jp.

Yuka Watanabe (Y)

Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Masaya Kumamoto (M)

Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Yuko Ichimiya (Y)

Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Soichi Mizuguchi (S)

Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Kanako Higashi (K)

Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Wakato Matsuoka (W)

Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Emergency and Critical Care Center, Kyushu University Hospital, Fukuoka, Japan.

Yoshitomo Motomura (Y)

Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Masafumi Sanefuji (M)

Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Akio Hiwatashi (A)

Department of Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Yasunari Sakai (Y)

Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Shouichi Ohga (S)

Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

Recherchemedicale.com › Personnes › Tranches d'âge › Adolescent › Predictive values of early head computed...
Recherchemedicale.com › Système nerveux › Système nerveux central › Encéphale › Predictive values of early head computed...
Recherchemedicale.com › Plaies et blessures › Traumatismes du système nerveux › Traumatismes cranioencéphaliques › Lésions encéphaliques › Predictive values of early head computed...
Recherchemedicale.com › Personnes › Tranches d'âge › Enfant › Predictive values of early head computed...
Recherchemedicale.com › Personnes › Tranches d'âge › Enfant › Enfant d'âge préscolaire › Predictive values of early head computed...
Recherchemedicale.com › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Analyse de survie › Survie sans rechute › Predictive values of early head computed...
Recherchemedicale.com › Régions du corps › Tête › Predictive values of early head computed...
Recherchemedicale.com › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Predictive values of early head computed...
Recherchemedicale.com › Personnes › Tranches d'âge › Nourrisson › Predictive values of early head computed...
Recherchemedicale.com › Personnes › Tranches d'âge › Nourrisson › Nouveau-né › Predictive values of early head computed...
Recherchemedicale.com › Techniques d'investigation › Neuroimagerie › Predictive values of early head computed...
Recherchemedicale.com › Maladies cardiovasculaires › Cardiopathies › Arrêt cardiaque › Arrêt cardiaque hors hôpital › Predictive values of early head computed...
Recherchemedicale.com › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Projets pilotes › Predictive values of early head computed...
Recherchemedicale.com › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études rétrospectives › Predictive values of early head computed...
Recherchemedicale.com › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Collecte de données › Registre civil › Mortalité › Taux de survie › Predictive values of early head computed...
Recherchemedicale.com › Diagnostic › Techniques et procédures diagnostiques › Imagerie diagnostique › Tomographie › Tomographie à rayons X › Tomodensitométrie › Predictive values of early head computed...