A Study of Vitamin D Level in Critically Ill Patients and Effect of Supplementation on Clinical Outcome.
Critical illness
Vitamin D
mechanical ventilation
mortality
Journal
Anesthesia, essays and researches
ISSN: 0259-1162
Titre abrégé: Anesth Essays Res
Pays: India
ID NLM: 101578762
Informations de publication
Date de publication:
Historique:
received:
27
08
2020
revised:
07
09
2020
accepted:
09
09
2020
entrez:
7
6
2021
pubmed:
8
6
2021
medline:
8
6
2021
Statut:
ppublish
Résumé
Supplementation of Vitamin-D in Vitamin-D deficient patients may reduce morbidity and mortality in critically ill patients in ICU. The aim of this study is to investigate serum level of Vitamin-D in critically ill patients and supplementation of vitamin-D in deficient patients and finally to compare clinical outcomes between two groups. Randomized, prospective and comparative study. In this study, serum vitamin-D level was investigated in recruited patients and vitamin-D deficient patients were randomly allocated into two groups viz; group-1, group-2. Vitamin-D (sachet CALCIROL 60,000 IU) supplementation was done once a week and twice a week in in group-1 and group-2 respectively, clinical outcomes between two groups were compared in terms of length of ICU stay, need for inotropic support, need for mechanical ventilation and 28 days ICU mortality. Mean and standard deviation were calculated. Test of analysis between two groups was done by No significant difference was found between two groups whether vitamin D supplementation done once or twice weekly ( From the above results we concluded that vitamin D supplementation in high dosages may be started in all critically ill patients, who are deficient in serum vitamin D level to get better clinical outcomes.
Sections du résumé
BACKGROUND
BACKGROUND
Supplementation of Vitamin-D in Vitamin-D deficient patients may reduce morbidity and mortality in critically ill patients in ICU.
AIMS AND OBJECTIVES
OBJECTIVE
The aim of this study is to investigate serum level of Vitamin-D in critically ill patients and supplementation of vitamin-D in deficient patients and finally to compare clinical outcomes between two groups.
SETTINGS AND DESIGN
METHODS
Randomized, prospective and comparative study.
MATERIALS AND METHODS
METHODS
In this study, serum vitamin-D level was investigated in recruited patients and vitamin-D deficient patients were randomly allocated into two groups viz; group-1, group-2. Vitamin-D (sachet CALCIROL 60,000 IU) supplementation was done once a week and twice a week in in group-1 and group-2 respectively, clinical outcomes between two groups were compared in terms of length of ICU stay, need for inotropic support, need for mechanical ventilation and 28 days ICU mortality.
STATISTICAL ANALYSIS
METHODS
Mean and standard deviation were calculated. Test of analysis between two groups was done by
RESULTS
RESULTS
No significant difference was found between two groups whether vitamin D supplementation done once or twice weekly (
CONCLUSION
CONCLUSIONS
From the above results we concluded that vitamin D supplementation in high dosages may be started in all critically ill patients, who are deficient in serum vitamin D level to get better clinical outcomes.
Identifiants
pubmed: 34092861
doi: 10.4103/aer.AER_83_20
pii: AER-14-474
pmc: PMC8159047
doi:
Types de publication
Journal Article
Langues
eng
Pagination
474-477Informations de copyright
Copyright: © 2020 Anesthesia: Essays and Researches.
Déclaration de conflit d'intérêts
There are no conflicts of interest.
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