Evaluation of Polymeric Matrix Loaded with Melatonin for Wound Dressing.
biopolymers
chitosan
collagen
cutaneous cells
melatonin
scaffolds
wound healing
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
26 May 2021
26 May 2021
Historique:
received:
29
04
2021
revised:
17
05
2021
accepted:
25
05
2021
entrez:
2
6
2021
pubmed:
3
6
2021
medline:
22
6
2021
Statut:
epublish
Résumé
The development of scaffolds mimicking the extracellular matrix containing bioactive substances has great potential in tissue engineering and wound healing applications. This study investigates melatonin-a methoxyindole present in almost all biological systems. Melatonin is a bioregulator in terms of its potential clinical importance for future therapies of cutaneous diseases. Mammalian skin is not only a prominent melatonin target, but also produces and rapidly metabolizes the multifunctional methoxyindole to biologically active metabolites. In our methodology, chitosan/collagen (CTS/Coll)-contained biomaterials are blended with melatonin at different doses to fabricate biomimetic hybrid scaffolds. We use rat tail tendon- and
Identifiants
pubmed: 34073402
pii: ijms22115658
doi: 10.3390/ijms22115658
pmc: PMC8197906
pii:
doi:
Substances chimiques
Collagen
9007-34-5
Chitosan
9012-76-4
Melatonin
JL5DK93RCL
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Deutsche Forschungsgemeinschaft
ID : KL2900/2-1
Organisme : Nicoluas Copernicus University in Torun
ID : 282/2021 IDUB SD
Références
J Pineal Res. 2019 Nov;67(4):e12610
pubmed: 31532834
Ann Biomed Eng. 2020 Dec;48(12):2924-2935
pubmed: 32929559
Int J Pharm. 2009 Nov 3;381(2):205-13
pubmed: 19596430
FEBS Lett. 2002 Jan 30;511(1-3):102-6
pubmed: 11821057
FASEB J. 2004 Mar;18(3):537-9
pubmed: 14715696
FASEB J. 2013 Jul;27(7):2742-55
pubmed: 23620527
Int J Mol Sci. 2014 Sep 30;15(10):17705-32
pubmed: 25272227
Int J Mol Sci. 2018 Nov 28;19(12):
pubmed: 30487387
Endocrinology. 2015 May;156(5):1630-6
pubmed: 25679869
Nanomedicine (Lond). 2020 Sep;15(22):2133-2147
pubmed: 32885718
Biomed Mater. 2017 Dec 15;13(1):015016
pubmed: 29244656
Biomaterials. 2018 Feb;154:213-222
pubmed: 29132046
Materials (Basel). 2020 Aug 17;13(16):
pubmed: 32824538
J Pineal Res. 2005 Apr;38(3):145-52
pubmed: 15725334
Cureus. 2017 Oct 2;9(10):e1736
pubmed: 29209583
FASEB J. 2004 May;18(7):869-71
pubmed: 15033929
J Natl Cancer Inst. 2009 Sep 16;101(18):1259-71
pubmed: 19704071
Biochim Biophys Acta. 1999 Oct 18;1472(1-2):206-14
pubmed: 10572942
Biol Rev Camb Philos Soc. 2010 Aug;85(3):607-23
pubmed: 20039865
J Pineal Res. 2004 Jan;36(1):1-9
pubmed: 14675124
Mol Reprod Dev. 2011 Apr;78(4):250-62
pubmed: 21381146
J Pineal Res. 2003 Jan;34(1):1-10
pubmed: 12485365
J Pineal Res. 2016 Sep;61(2):187-97
pubmed: 27117941
J Pineal Res. 2009 Nov;47(4):318-23
pubmed: 19817971
J Pineal Res. 2018 Nov;65(4):e12516
pubmed: 29935084
FEBS Lett. 1997 Oct 13;416(1):103-6
pubmed: 9369243
Trends Endocrinol Metab. 2008 Jan;19(1):17-24
pubmed: 18155917
Mater Sci Eng C Mater Biol Appl. 2018 Feb 1;83:195-201
pubmed: 29208279
Curr Neuropharmacol. 2017 Apr;15(3):434-443
pubmed: 28503116
Int J Pharm. 2021 Mar 1;596:120213
pubmed: 33493599
Mol Cell Endocrinol. 2012 Apr 4;351(2):152-66
pubmed: 22245784
FASEB J. 2002 Jun;16(8):896-8
pubmed: 12039872
J Exp Bot. 2009;60(1):57-69
pubmed: 19033551
J Clin Endocrinol Metab. 2003 Dec;88(12):5898-906
pubmed: 14671188
Biochemistry. 2005 Jul 5;44(26):9300-7
pubmed: 15981996
Fertil Steril. 2014 Aug;102(2):321-8
pubmed: 24996495
Int J Biol Macromol. 2020 Nov 1;162:1465-1475
pubmed: 32781118
Prog Retin Eye Res. 2005 Jul;24(4):433-56
pubmed: 15845344
Physiology (Bethesda). 2020 Mar 1;35(2):86-95
pubmed: 32024428
J Pineal Res. 1993 Sep;15(2):59-69
pubmed: 8283386
Int J Mol Sci. 2021 Feb 02;22(3):
pubmed: 33540815
J Pineal Res. 2014 Aug;57(1):90-102
pubmed: 24867336
Cell Mol Life Sci. 2017 Nov;74(21):3913-3925
pubmed: 28803347
Int J Mol Sci. 2016 Feb 18;17(2):160
pubmed: 26901191
Int J Biol Macromol. 2013 Jan;52:250-9
pubmed: 23063427
Carbohydr Polym. 2020 Jun 1;237:116159
pubmed: 32241409
Curr Top Med Chem. 2002 Feb;2(2):181-97
pubmed: 11899100
Reprod Fertil Dev. 2013;25(4):674-82
pubmed: 22951050
J Pineal Res. 2012 Mar;52(2):217-27
pubmed: 21884551
J Invest Dermatol. 2018 Mar;138(3):490-499
pubmed: 29428440
J Pineal Res. 2021 Apr;70(3):e12728
pubmed: 33650175
Acta Pharm. 2019 Dec 1;69(4):635-648
pubmed: 31639097
Molecules. 2021 Apr 25;26(9):
pubmed: 33923028
J Pineal Res. 2016 Oct;61(3):253-78
pubmed: 27500468
Crit Rev Biochem Mol Biol. 2009 Jul-Aug;44(4):175-200
pubmed: 19635037
Biomed Pharmacother. 2020 Dec;132:110887
pubmed: 33254429
Physiology (Bethesda). 2014 Sep;29(5):325-33
pubmed: 25180262
FASEB J. 2000 Sep;14(12):1677-9
pubmed: 10973915
IET Nanobiotechnol. 2020 Dec;14(9):830-832
pubmed: 33399115
Cell Mol Life Sci. 2007 Mar;64(6):781-90
pubmed: 17334663
J Pineal Res. 2007 Oct;43(3):232-8
pubmed: 17803519
Prog Biomater. 2020 Sep;9(3):115-123
pubmed: 32951173
Cancer Res. 1987 Feb 15;47(4):936-42
pubmed: 3802100
Endocr Rev. 1991 May;12(2):151-80
pubmed: 1649044