Evaluation of the relationship between KIM-1 and suPAR levels and clinical severity in COVID-19 patients: A different perspective on suPAR.
COVID-19
KIM-1
suPAR
Journal
Journal of medical virology
ISSN: 1096-9071
Titre abrégé: J Med Virol
Pays: United States
ID NLM: 7705876
Informations de publication
Date de publication:
Sep 2021
Sep 2021
Historique:
revised:
15
05
2021
received:
09
03
2021
accepted:
18
05
2021
pubmed:
22
5
2021
medline:
3
8
2021
entrez:
21
5
2021
Statut:
ppublish
Résumé
Coronavirus disease 2019 (COVID-19) is one of the most pressing health problems of this century, but our knowledge of the disease is still limited. In this study, we aimed to examine serum-soluble urokinase plasminogen activator receptor (suPAR) and kidney injury molecule 1 (KIM-1) levels based on the clinical course of COVID-19. Our study included 102 patients over the age of 18 who were diagnosed as having COVID-19 between September 2020 and December 2020 and a control group of 50 health workers over the age of 18 whose severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) PCR results were negative. KIM-1 was measured by ELISA and suPAR by suPARnostic™ assay. Analysis of previously identified variables of prognostic significance in COVID-19 revealed high neutrophil to lymphocyte ratio, lactose dehydrogenase, prothrombin time, C-reactive protein, PaO
Identifiants
pubmed: 34019703
doi: 10.1002/jmv.27099
pmc: PMC8242801
doi:
Substances chimiques
Biomarkers
0
HAVCR1 protein, human
0
Hepatitis A Virus Cellular Receptor 1
0
PLAUR protein, human
0
Receptors, Urokinase Plasminogen Activator
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
5568-5573Informations de copyright
© 2021 Wiley Periodicals LLC.
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