Injury Prevention and long-term Outcomes following Trauma-the IPOT project: a protocol for prospective nationwide registry-based studies in Norway.

Case-Control Studies Humans Norway / epidemiology Prospective Studies Registries Risk Factors
anaesthetics clinical pharmacology epidemiology orthopaedic & trauma surgery pain management

Journal

BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874

Informations de publication

Date de publication:
18 05 2021
Historique:
entrez: 19 5 2021
pubmed: 20 5 2021
medline: 5 6 2021
Statut: epublish

Résumé

Traumatic injuries constitute a major cause of mortality and morbidity. Still, the public health burden of trauma in Norway has not been characterised using nationwide registry data. More knowledge is warranted on trauma risk factors and the long-term outcomes following trauma. The Injury Prevention and long-term Outcomes following Trauma project will establish a comprehensive research database. The Norwegian National Trauma Registry (NTR) will be merged with several data sources to pursue the following three main research topics: (1) the public health burden of trauma to society (eg, excess mortality and disability-adjusted life-years (DALYs)), (2) trauma aetiology (eg, socioeconomic factors, comorbidity and drug use) and (3) trauma survivorship (eg, survival, drug use, use of welfare benefits, work ability, education and income). The NTR (n≈27 000 trauma patients, 2015-2018) will be coupled with the data from Statistics Norway, the Norwegian Patient Registry, the Cause of Death Registry, the Registry of Primary Health Care and the Norwegian Prescription Database. To quantify the public health burden, DALYs will be calculated from the NTR. To address trauma aetiology, we will conduct nested case-control studies with 10 trauma-free controls (drawn from the National Population Register) matched to each trauma case on birth year, sex and index date. Conditional logistic regression models will be used to estimate trauma risk according to relevant exposures. To address trauma survivorship, we will use cohort and matched cohort designs and time-to-event analyses to examine various post-trauma outcomes. The project is approved by the Regional Committee for Medical Research Ethics. The project's data protection impact assessment is approved by the data protection officer. Results will be disseminated to patients, in peer-reviewed journals, at conferences and in the media.

Identifiants

DOI: 10.1136/bmjopen-2020-046954 PMID: 34006552 PMC: PMC8137183
pubmed: 34006552
pii: bmjopen-2020-046954
doi: 10.1136/bmjopen-2020-046954
pmc: PMC8137183
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e046954

Informations de copyright

© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Références

JAMA. 2016 Jun 14;315(22):2415-23
pubmed: 27299617
Tidsskr Nor Laegeforen. 2020 Oct 19;140(15):
pubmed: 33118769
Eur J Pain. 2010 Mar;14(3):289-94
pubmed: 19505834
Occup Environ Med. 2007 May;64(5):325-33
pubmed: 17182643
J Chronic Dis. 1987;40(5):373-83
pubmed: 3558716
J Trauma. 2007 Feb;62(2):471-81
pubmed: 17297338
Injury. 2017 Nov;48(11):2470-2477
pubmed: 28964511
J Trauma. 2002 Apr;52(4):660-6
pubmed: 11956379
J Trauma. 2011 Aug;71(2):435-41
pubmed: 21427614
J Pediatr Surg. 1998 Sep;33(9):1388-92
pubmed: 9766360
J Trauma. 2007 Feb;62(2):461-70
pubmed: 17297337
J Trauma Acute Care Surg. 2013 May;74(5):1195-205
pubmed: 23609267
Accid Anal Prev. 2017 Dec;109:123-131
pubmed: 29059534
J Bone Joint Surg Am. 2014 Mar 19;96(6):495-9
pubmed: 24647506
Adv Med Sci. 2009;54(1):20-6
pubmed: 19586835
Ann Surg. 2016 Apr;263(4):623-32
pubmed: 26779977
Sleep. 2012 Jun 01;35(6):825-34
pubmed: 22654202
Lancet. 2012 Jan 7;379(9810):55-70
pubmed: 22225671
BMC Psychiatry. 2018 Jun 13;18(1):188
pubmed: 29895273
BMJ. 2001 Jul 21;323(7305):141
pubmed: 11463683
Scand J Trauma Resusc Emerg Med. 2008 Aug 28;16:7
pubmed: 18957069
Stat Med. 2000 Feb 15;19(3):335-51
pubmed: 10649300
Clin Epidemiol. 2014 Oct 24;6:395-404
pubmed: 25368532
Bull World Health Organ. 1994;72(3):429-45
pubmed: 8062401
J Epidemiol Community Health. 2010 Nov;64(11):998-1003
pubmed: 19822556
Int J Epidemiol. 1993 Dec;22(6):1189-92
pubmed: 8144304
Lancet. 2018 Nov 10;392(10159):1789-1858
pubmed: 30496104
Ann Surg. 2019 May;269(5):972-978
pubmed: 29342014
JAMA. 2016 Nov 1;316(17):1818-1819
pubmed: 27802529
Pain. 2011 Jul;152(7):1555-1561
pubmed: 21450405
Occup Environ Med. 1994 Sep;51(9):612-6
pubmed: 7951793
Inj Prev. 2012 Feb;18(1):3-9
pubmed: 21606470
Clin Pharmacol Ther. 2009 Jun;85(6):596-9
pubmed: 19279562
Biom J. 2011 Mar;53(2):332-50
pubmed: 21374697
N Engl J Med. 2016 Mar 31;374(13):1253-63
pubmed: 27028915
Epidemiol Rev. 2003;25:43-50
pubmed: 12923989
BMC Public Health. 2014 Jul 29;14:765
pubmed: 25074692
Pain. 2016 Aug;157(8):1626-33
pubmed: 26989805
Lancet. 2015 Nov 28;386(10009):2145-91
pubmed: 26321261
Occup Environ Med. 2005 Mar;62(3):172-80
pubmed: 15723882
J Trauma Acute Care Surg. 2015 Mar;78(3):628-33
pubmed: 25710437
Br J Surg. 2019 Jan;106(1):65-73
pubmed: 30221344
Ann Epidemiol. 2007 Aug;17(8):597-602
pubmed: 17574863
N Engl J Med. 2010 Nov 18;363(21):1981-5
pubmed: 21083382
Acta Anaesthesiol Scand. 2018 Feb;62(2):253-266
pubmed: 29119562

Auteurs

Jo Steinson Stenehjem (JS)

Department of Research and Development, Division of Emergencies and Critical Care, Oslo University Hospital, Oslo, Norway jo.stenehjem@kreftregisteret.no.
Department of Biostatistics, Oslo Centre for Biostatistics and Epidemiology, University of Oslo, Oslo, Norway.
Department of Research, Cancer Registry of Norway, Oslo, Norway.
ORCID: 0000-0002-1964-5410

Olav Røise (O)

The Norwegian National Trauma Registry, Division of Orthopedic Surgery, Oslo University Hospital, Oslo, Norway.
Faculty of Health Sciences, SHARE - Centre for Resilience in Healthcare, University of Stavanger, Stavanger, Norway.
Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
ORCID: 0000-0003-4931-7001

Trond Nordseth (T)

Department of Research and Development, Division of Emergencies and Critical Care, Oslo University Hospital, Oslo, Norway.
Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.
Department of Anesthesia and Intensive Care Medicine, St.Olav Hospital, Trondheim, Norway.

Thomas Clausen (T)

Norwegian Centre for Addiction Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

Bård Natvig (B)

Department of General Practice, Institute of Health and Society, University of Oslo, Oslo, Norway.

Svetlana O Skurtveit (S)

Norwegian Centre for Addiction Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Department of Mental Disorders, Division of Mental and Physical Health, Norwegian Institute of Public Health, Oslo, Norway.

Torsten Eken (T)

Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Department of Anesthesiology, Division of Emergencies and Critical Care, Oslo University Hospital, Oslo, Norway.
ORCID: 0000-0002-5943-4538

Thomas Kristiansen (T)

Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Department of Anesthesiology, Division of Emergencies and Critical Care, Oslo University Hospital, Oslo, Norway.

Jon Michael Gran (JM)

Department of Biostatistics, Oslo Centre for Biostatistics and Epidemiology, University of Oslo, Oslo, Norway.

Leiv Arne Rosseland (LA)

Department of Research and Development, Division of Emergencies and Critical Care, Oslo University Hospital, Oslo, Norway.
Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

Recherchemedicale.com › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études cas-témoins › Injury Prevention and long-term Outcomes...
Recherchemedicale.com › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Injury Prevention and long-term Outcomes...
Recherchemedicale.com › Régions géographiques › Europe › Pays nordiques et scandinaves › Norvège › Injury Prevention and long-term Outcomes...
Recherchemedicale.com › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études prospectives › Injury Prevention and long-term Outcomes...
Recherchemedicale.com › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Collecte de données › Enregistrements › Injury Prevention and long-term Outcomes...
Recherchemedicale.com › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Probabilité › Risque › Facteurs de risque › Injury Prevention and long-term Outcomes...