BMI
Obesity
TCF7L2
Type 2 diabetes
rs7903146
Journal
PeerJ
ISSN: 2167-8359
Titre abrégé: PeerJ
Pays: United States
ID NLM: 101603425
Informations de publication
Date de publication:
2021
2021
Historique:
received:
27
10
2020
accepted:
04
04
2021
entrez:
17
5
2021
pubmed:
18
5
2021
medline:
18
5
2021
Statut:
epublish
Résumé
Type 2 diabetes mellitus (T2DM) and obesity are complex pandemic diseases in the 21st century. Worldwide, the T allele rs7903146 in the A total of 1,023 participants from an elderly census-based cohort called SABE (Saúde, Bem Estar e Envelhecimento-Health, Well-Being and Aging) were stratified by BMI status and type 2 diabetes presence. The The association between the rs7903146 T allele and T2DM was inversely proportional to the BMI status, with an increased risk in the normal weight group (OR 3.36; 95% CI [1.46-7.74]; We confirmed that the rs7903146 is both associated with T2DM and obesity. The
Sections du résumé
BACKGROUND
BACKGROUND
Type 2 diabetes mellitus (T2DM) and obesity are complex pandemic diseases in the 21st century. Worldwide, the T allele rs7903146 in the
METHODS
METHODS
A total of 1,023 participants from an elderly census-based cohort called SABE (Saúde, Bem Estar e Envelhecimento-Health, Well-Being and Aging) were stratified by BMI status and type 2 diabetes presence. The
RESULTS
RESULTS
The association between the rs7903146 T allele and T2DM was inversely proportional to the BMI status, with an increased risk in the normal weight group (OR 3.36; 95% CI [1.46-7.74];
CONCLUSION
CONCLUSIONS
We confirmed that the rs7903146 is both associated with T2DM and obesity. The
Identifiants
pubmed: 33996288
doi: 10.7717/peerj.11349
pii: 11349
pmc: PMC8106398
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e11349Informations de copyright
© 2021 Bride et al.
Déclaration de conflit d'intérêts
The authors declare that they have no competing interests.
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