Normalizing Clinical Document Titles to LOINC Document Ontology: an Initial Study.


Journal

AMIA ... Annual Symposium proceedings. AMIA Symposium
ISSN: 1942-597X
Titre abrégé: AMIA Annu Symp Proc
Pays: United States
ID NLM: 101209213

Informations de publication

Date de publication:
2020
Historique:
entrez: 3 5 2021
pubmed: 4 5 2021
medline: 14 7 2021
Statut: epublish

Résumé

The normalization of clinical documents is essential for health information management with the enormous amount of clinical documentation generated each year. The LOINC Document Ontology (DO) is a universal clinical document standard in a hierarchical structure. The objective of this study is to investigate the feasibility and generalizability of LOINC DO by mapping from clinical note titles across five institutions to five DO axes. We first developed an annotation framework based on the definition of LOINC DO axes and manually mapped 4,000 titles. Then we introduced a pre-trained deep learning model named Bidirectional Encoder Representations from Transformers (BERT) to enable automatic mapping from titles to LOINC DO axes. The results showed that the BERT-based automatic mapping achieved improved performance compared with the baseline model. By analyzing both manual annotations and predicted results, ambiguities in LOINC DO axes definition were discussed.

Identifiants

pubmed: 33936520
pii: 181_3416722
pmc: PMC8075502

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1441-1450

Subventions

Organisme : NCATS NIH HHS
ID : U01 TR002062
Pays : United States
Organisme : NCI NIH HHS
ID : U24 CA194215
Pays : United States

Informations de copyright

©2020 AMIA - All rights reserved.

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Auteurs

Xu Zuo (X)

School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.

Jianfu Li (J)

School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.

Bo Zhao (B)

School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.

Yujia Zhou (Y)

School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.

Xiao Dong (X)

School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.

Jon Duke (J)

Georgia Institute of Technology, Atlanta, GA, USA.
OHDSI Consortium, Natural Language Processing Working Group.

Karthik Natarajan (K)

Columbia University, New York City, NY, USA.
OHDSI Consortium, Natural Language Processing Working Group.

George Hripcsak (G)

Columbia University, New York City, NY, USA.
OHDSI Consortium, Natural Language Processing Working Group.

Nigam Shah (N)

Stanford University, Stanford, CA, USA.
OHDSI Consortium, Natural Language Processing Working Group.

Juan M Banda (JM)

Georgia State University, Atlanta, GA, USA.
OHDSI Consortium, Natural Language Processing Working Group.

Ruth Reeves (R)

Department of Veterans Affairs, Tennessee Valley Healthcare System, Nashville, TN, USA.
OHDSI Consortium, Natural Language Processing Working Group.

Timothy Miller (T)

Boston Children's Hospital, Boston, MA, USA.
OHDSI Consortium, Natural Language Processing Working Group.

Hua Xu (H)

School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.
OHDSI Consortium, Natural Language Processing Working Group.

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