Association of interleukin-12B rs6887695 with susceptibility to allergic rhinitis.
Allergic rhinitis
IL12B gene
Single-nucleotide polymorphism
Journal
Immunologic research
ISSN: 1559-0755
Titre abrégé: Immunol Res
Pays: United States
ID NLM: 8611087
Informations de publication
Date de publication:
04 2021
04 2021
Historique:
received:
12
11
2020
accepted:
30
03
2021
pubmed:
10
4
2021
medline:
27
1
2022
entrez:
9
4
2021
Statut:
ppublish
Résumé
Interleukin-12 (IL-12) is a heterodimeric cytokine encoded by two separate genes, IL12A and IL12B, which may play a regulatory role in allergen-induced inflammation through CD4
Identifiants
pubmed: 33834388
doi: 10.1007/s12026-021-09189-1
pii: 10.1007/s12026-021-09189-1
doi:
Substances chimiques
Biomarkers
0
IL12B protein, human
0
Interleukin-12 Subunit p40
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
189-195Subventions
Organisme : Kermanshah University of Medical Sciences
ID : 96608
Références
Varshney J, Varshney H. Allergic rhinitis: an overview. Indian J Otolaryngol Head Neck Surg. 2015;67(2):143–9.
pubmed: 26075169
pmcid: 4460099
doi: 10.1007/s12070-015-0828-5
Gu ZW, Wang YX, Cao ZW. Neutralization of interleukin-17 suppresses allergic rhinitis symptoms by downregulating Th2 and Th17 responses and upregulating the Treg response. Oncotarget. 2017;8(14):22361.
pubmed: 28423590
pmcid: 5410229
doi: 10.18632/oncotarget.15652
Aly MAG, El Tabbakh MT, Heissam WF, Abbadi SH. The study of a possible correlation between serum levels of interleukin 17 and clinical severity in patients with allergic rhinitis. Allergy Rhinol. 2017;8(3):ar. 2017.8. 0207.
Yao J, Zhou H, Xu M, Zhang Y. Relationship between GATA-3 and IL-12 in patients with allergic rhinitis. Lin Chuang er bi yan hou tou Jing wai ke za zhi= J Clin Otorhinolaryngol Head Neck Surg. 2007;21(23):1087–9.
Ying S, Durham SR, Corrigan CJ, Hamid Q, Kay AB. Phenotype of cells expressing mRNA for TH2-type (interleukin 4 and interleukin 5) and TH1-type (interleukin 2 and interferon gamma) cytokines in bronchoalveolar lavage and bronchial biopsies from atopic asthmatic and normal control subjects. Am J Respir Cell Mol Biol. 1995;12(5):477–87.
pubmed: 7742012
doi: 10.1165/ajrcmb.12.5.7742012
Tang M, Coleman J, Kemp A. Interleukin-4 and interferon-gamma production in atopic and non-atopic children with ashma. Clin Exp Allergy. 1995;25(6):515–21.
pubmed: 7648458
doi: 10.1111/j.1365-2222.1995.tb01088.x
Fan Y, Piao CH, Hyeon E, Jung SY, Eom J-E, Shin HS, et al. Gallic acid alleviates nasal inflammation via activation of Th1 and inhibition of Th2 and Th17 in a mouse model of allergic rhinitis. Int Immunopharmacol. 2019;70:512–9.
pubmed: 30884431
doi: 10.1016/j.intimp.2019.02.025
Trinchieri G, Pflanz S, Kastelein RA. The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses. Immunity. 2003;19(5):641–4.
pubmed: 14614851
doi: 10.1016/S1074-7613(03)00296-6
Teng MW, Bowman EP, McElwee JJ, Smyth MJ, Casanova J-L, Cooper AM, et al. IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases. Nat Med. 2015;21(7):719–29.
pubmed: 26121196
doi: 10.1038/nm.3895
Trinchieri G. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat Rev Immunol. 2003;3(2):133–46.
pubmed: 12563297
doi: 10.1038/nri1001
Wang D-Y. Risk factors of allergic rhinitis: genetic or environmental? Ther Clin Risk Manag. 2005;1(2):115.
pubmed: 18360551
pmcid: 1661616
doi: 10.2147/tcrm.1.2.115.62907
Li J, Zhang Y, Zhang L. Discovering susceptibility genes for allergic rhinitis and allergy using a genome-wide association study strategy. Curr Opin Allergy Clin Immunol. 2015;15(1):33–40.
pubmed: 25304232
doi: 10.1097/ACI.0000000000000124
Wei P, Kou W, Sun R, Hu G-H, Hu D, Feng J, et al. Association study between interleukin-12 receptor β1/β2 genes and allergic rhinitis in the Chinese Han population. Eur Arch Oto-Rhino-Laryngol. 2015;272(4):889–93.
doi: 10.1007/s00405-014-3145-9
Wei P, Kou W, Zhang C, Kang H, Yao H, Tang X, et al. Genetic variations in interleukin-12B in allergic rhinitis. Immunol Res. 2016;64(1):329–36.
pubmed: 26663019
doi: 10.1007/s12026-015-8758-6
Moh’d Al-Rawashdeh B, Sadaalhanjori A, Ali E, Zihlif M. Association of IL-4 polymorphisms with allergic rhinitis in Jordanian population. Medicina. 2020;56(4):179.
pmcid: 7230575
doi: 10.3390/medicina56040179
Hu D, Hu G, Zhu J, Shen Y, Kang H, Hong S. Association between polymorphisms of the IL-23R gene and allergic rhinitis in a Chinese Han population. PLoS ONE. 2013;8(5):e63858.
pubmed: 23696856
pmcid: 3655942
doi: 10.1371/journal.pone.0063858
Wang M, Zhang Y, Han D, Zhang L. Association between polymorphisms in cytokine genes IL-17A and IL-17F and development of allergic rhinitis and comorbid asthma in Chinese subjects. Hum Immunol. 2012;73(6):647–53.
pubmed: 22507625
doi: 10.1016/j.humimm.2012.03.010
Nasiri R, Hirbod-Mobarakeh A, Movahedi M, Farhadi E, Ansaripour B, Amirzargar A, et al. Gene polymorphisms of interleukin-10 and transforming growth factor beta in allergic rhinitis. Allergol Immunopathol. 2016;44(2):125–30.
doi: 10.1016/j.aller.2015.05.010
Davila I, Mullol J, Ferrer M, Bartra J, Del Cuvillo A, Montoro J, et al. Genetic aspects of allergic rhinitis. J Investig Allergol Clin Immunol. 2009;19(Suppl 1):25–31.
pubmed: 19476051
Nakajima H, Takatsu K. Role of cytokines in allergic airway inflammation. Int Arch Allergy Immunol. 2007;142(4):265–73.
pubmed: 17124428
doi: 10.1159/000097357
Collins FS, Brooks LD, Chakravarti A. A DNA polymorphism discovery resource for research on human genetic variation. Genome Res. 1998;8(12):1229–31.
pubmed: 9872978
doi: 10.1101/gr.8.12.1229
Shastry BS. SNPs: impact on gene function and phenotype. Methods Mol Biol. 2009;578:3–22
Kimura-Kataoka K, Yasuda T, Fujihara J, Toga T, Ono RI, Otsuka Y, et al. Genetic and expression analysis of SNP s in the human deoxyribonuclease II: SNP s in the promoter region reduce its in vivo activity through decreased promoter activity. Electrophoresis. 2012;33(18):2852–8.
pubmed: 23019102
doi: 10.1002/elps.201200260
Milanese M, Segat L, Crovella S. Transcriptional effect of DEFB1 gene 5′ untranslated region polymorphisms. Cancer Res. 2007;67(12):5997.
pubmed: 17575171
doi: 10.1158/0008-5472.CAN-06-3544
Zhu K-J, Zhu C-Y, Shi G, Fan Y-M. Meta-analysis of IL12B polymorphisms (rs3212227, rs6887695) with psoriasis and psoriatic arthritis. Rheumatol Int. 2013;33(7):1785–90.
pubmed: 23297015
doi: 10.1007/s00296-012-2637-4
Li J, Zhang C, Wang J-B, Chen S-S, Zhang T-P, Li S, et al. Relationship between the IL12B (rs3212227) gene polymorphism and susceptibility to multiple autoimmune diseases: a meta-analysis. Mod Rheumatol. 2016;26(5):749–56.
pubmed: 26915668
doi: 10.3109/14397595.2016.1157282
Wang X, Du K, She W, Ouyang Y, Sima Y, Liu C, et al. Recent advances in the diagnosis of allergic rhinitis. Expert Rev Clin Immunol. 2018;14(11):957–64.
pubmed: 30261765
doi: 10.1080/1744666X.2018.1530113
Chen T, Liang W, Gao L, Wang Y, Liu Y, Zhang L, et al. Association of single nucleotide polymorphisms in interleukin 12 (IL-12A and-B) with asthma in a Chinese population. Hum Immunol. 2011;72(7):603–6.
pubmed: 21513752
doi: 10.1016/j.humimm.2011.03.018
Wu Y, Lu Z, Chen Y, Xue F, Chen X, Zheng J. Replication of association between interleukin-23 receptor (IL-23R) and its ligand (IL12B) polymorphisms and psoriasis in the Chinese Han population. Hum Immunol. 2010;71(12):1255–8.
pubmed: 20875477
doi: 10.1016/j.humimm.2010.09.014
Javan MR, Shahraki S, Safa A, Zamani MR, Salmaninejad A, Aslani S. An interleukin 12 B single nucleotide polymorphism increases IL-12p40 production and is associated with increased disease susceptibility in patients with relapsing-remitting multiple sclerosis. Neurol Res. 2017;39(5):435–41.
pubmed: 28276258
doi: 10.1080/01616412.2017.1301623
Durrant D, Metzger D. IL-12 can alleviate Th17-mediated allergic lung inflammation through induction of pulmonary IL-10 expression. Mucosal Immunol. 2010;3(3):301–11.
pubmed: 20237464
doi: 10.1038/mi.2010.9
Manolova I, Ivanova M, Vasilev G, Stoilov R, Miteva L, Stanilova S. Impact of IL12B polymorphisms on genetic susceptibility and IL-12p40 and IL-23 serum levels in rheumatoid arthritis. Immunol Invest. 2020;49(1–2):1–14.
pubmed: 31161840
doi: 10.1080/08820139.2019.1622561
Eskandari-Nasab E, Moghadampour M, Asadi-Saghandi A, Kharazi-Nejad E, Rezaeifar A, Pourmasoumi H. Levels of interleukin-(IL)-12p40 are markedly increased in brucellosis among patients with specific IL-12B genotypes. Scand J Immunol. 2013;78(1):85–91.
pubmed: 23578145
doi: 10.1111/sji.12054
Shen T-C, Tsai C-W, Chang W-S, Wang S, Chao C-Y, Hsiao C-L, et al. Association of interleukin-12A rs568408 with susceptibility to asthma in Taiwan. Sci Rep. 2017;7(1):1–7.
doi: 10.1038/s41598-016-0028-x
Xiao J-P, Wang X-R, Zhang S, Wang H-Y, Ye L, Pan H-F, et al. Association between rs6887695 and 3′-untranslated region polymorphisms within the interleukin-12B gene and susceptibility to autoimmune diseases in Asian and European population: a meta-analysis. Autoimmunity. 2016;49(4):277–84.
pubmed: 27068848
doi: 10.3109/08916934.2016.1166215