Efficacy and safety of grasping forceps-assisted endoscopic resection for gastric neoplasms: A multi-centre retrospective study.

Endoscopic mucosal resection Endoscopic resection Endoscopic submucosal dissection Gastric cancer Grasping forceps-assisted endoscopic resection

Journal

World journal of gastrointestinal oncology
ISSN: 1948-5204
Titre abrégé: World J Gastrointest Oncol
Pays: China
ID NLM: 101532470

Informations de publication

Date de publication:
15 Mar 2021
Historique:
received: 10 12 2020
revised: 09 01 2021
accepted: 01 02 2021
entrez: 19 3 2021
pubmed: 20 3 2021
medline: 20 3 2021
Statut: ppublish

Résumé

Endoscopic submucosal dissection (ESD) is widely accepted for early gastric cancer (EGC) without lymph node metastasis, although ESD is challenging, even for small lesions, in the greater curvature (GC) of the upper (U) and middle (M) thirds of the stomach. Grasping forceps-assisted endoscopic resection (GF-ER) is a type of endoscopic mucosal resection that is performed To investigate the safety and efficacy of GF-ER We retrospectively reviewed the medical records of 506 patients who underwent ER of 522 EGC lesions in the stomach's U and M regions in three institutions between January 2016 and May 2020. Nine lesions from eight patients who underwent GF-ER for EGC (the GF-ER group) were compared to 63 lesions from 63 patients who underwent ESD (the ESD group). We also performed a subgroup analysis of small lesions (≤ 10 mm) in 6 patients (7 lesions) from the GF-ER group and 20 patients (20 lesions) from the ESD group. There were no statistically significant differences between the GF-ER and ESD groups in the These findings suggest that GF-ER may be an effective therapeutic option for small lesions in the GC of the stomach's U and M regions.

Sections du résumé

BACKGROUND BACKGROUND
Endoscopic submucosal dissection (ESD) is widely accepted for early gastric cancer (EGC) without lymph node metastasis, although ESD is challenging, even for small lesions, in the greater curvature (GC) of the upper (U) and middle (M) thirds of the stomach. Grasping forceps-assisted endoscopic resection (GF-ER) is a type of endoscopic mucosal resection that is performed
AIM OBJECTIVE
To investigate the safety and efficacy of GF-ER
METHODS METHODS
We retrospectively reviewed the medical records of 506 patients who underwent ER of 522 EGC lesions in the stomach's U and M regions in three institutions between January 2016 and May 2020. Nine lesions from eight patients who underwent GF-ER for EGC (the GF-ER group) were compared to 63 lesions from 63 patients who underwent ESD (the ESD group). We also performed a subgroup analysis of small lesions (≤ 10 mm) in 6 patients (7 lesions) from the GF-ER group and 20 patients (20 lesions) from the ESD group.
RESULTS RESULTS
There were no statistically significant differences between the GF-ER and ESD groups in the
CONCLUSION CONCLUSIONS
These findings suggest that GF-ER may be an effective therapeutic option for small lesions in the GC of the stomach's U and M regions.

Identifiants

pubmed: 33738045
doi: 10.4251/wjgo.v13.i3.174
pmc: PMC7953346
doi:

Types de publication

Journal Article

Langues

eng

Pagination

174-184

Informations de copyright

©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflict-of-interest statement: The authors declare that they have no conflict-of-interests.

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Auteurs

Ryoji Ichijima (R)

Division of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of Medicine, Chiyoda-ku 101-0062, Tokyo, Japan. ryoji0331@yahoo.co.jp.

Sho Suzuki (S)

Division of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of Medicine, Chiyoda-ku 101-0062, Tokyo, Japan.

Mitsuru Esaki (M)

Division of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of Medicine, Chiyoda-ku 101-0062, Tokyo, Japan.

Toshiki Horii (T)

Division of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of Medicine, Chiyoda-ku 101-0062, Tokyo, Japan.

Chika Kusano (C)

Division of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of Medicine, Chiyoda-ku 101-0062, Tokyo, Japan.

Hisatomo Ikehara (H)

Division of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of Medicine, Chiyoda-ku 101-0062, Tokyo, Japan.

Takuji Gotoda (T)

Division of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of Medicine, Chiyoda-ku 101-0062, Tokyo, Japan.

Classifications MeSH