Platelet hyaluronidase 2 enrichment in acute coronary syndromes: a conceivable role in monocyte-platelet aggregate formation.
Acute Coronary Syndrome
/ drug therapy
Cell Adhesion Molecules
/ antagonists & inhibitors
Coculture Techniques
GPI-Linked Proteins
/ antagonists & inhibitors
Humans
Hyaluronic Acid
/ metabolism
Hyaluronoglucosaminidase
/ antagonists & inhibitors
Monocytes
/ drug effects
Platelet Aggregation
/ drug effects
Acute coronary syndromes
hyaluronic acid
hyaluronidase
personalised medicine
platelets
Journal
Journal of enzyme inhibition and medicinal chemistry
ISSN: 1475-6374
Titre abrégé: J Enzyme Inhib Med Chem
Pays: England
ID NLM: 101150203
Informations de publication
Date de publication:
Dec 2021
Dec 2021
Historique:
entrez:
18
3
2021
pubmed:
19
3
2021
medline:
17
7
2021
Statut:
ppublish
Résumé
Acute Coronary Syndromes (ACS) with plaque erosion display dysregulated hyaluronan metabolism, with increased hyaluronidase-2 (HYAL2) expression. However, the expression and the role of this enzyme on platelets has never been explored. We evaluated the platelet's HYAL2 (
Identifiants
pubmed: 33733989
doi: 10.1080/14756366.2021.1900159
pmc: PMC7993372
doi:
Substances chimiques
Cell Adhesion Molecules
0
GPI-Linked Proteins
0
Hyaluronic Acid
9004-61-9
Hyal2 protein, human
EC 3.2.1.25
Hyaluronoglucosaminidase
EC 3.2.1.35
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
785-789Références
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