Abortion-related near-miss morbidity and mortality in 43 health facilities with differences in readiness to provide abortion care in Uganda.


Journal

BMJ global health
ISSN: 2059-7908
Titre abrégé: BMJ Glob Health
Pays: England
ID NLM: 101685275

Informations de publication

Date de publication:
02 2021
Historique:
received: 28 06 2020
revised: 12 01 2021
accepted: 20 01 2021
entrez: 6 2 2021
pubmed: 7 2 2021
medline: 25 6 2021
Statut: ppublish

Résumé

With a view to inform policy for improved postabortion care, we describe abortion-related near-miss and mortality by sociodemographic risk factors and management options by pregnancy trimester in Uganda. This secondary data analysis used an adapted WHO near-miss methodology to collect cross-sectional maternal near-miss and abortion complications data at 43 health facilities in Central and Eastern Uganda in 2016-2017. We computed abortion severe morbidity, near-miss and mortality ratios per 100 000 live births, and described the proportion of cases that worsened to an abortion near-miss or death, stratified by geographical region and trimester. We tested for association between independent variables and abortion near-miss, and obtained prevalence ratios for association between second trimester near-miss and independent demographic and management indicators. We assessed health facility readiness for postabortion care provision in Central and Eastern regions. Of 3315 recorded severe abortion morbidity cases, 1507 were near-misses. Severe abortion morbidity, near-miss and mortality ratios were 2063, 938 and 23 per 100 000 live births, respectively. Abortion-related mortality ratios were 11 and 57 per 100 000 in Central and Eastern regions, respectively. Abortion near-miss cases were significantly associated with referral (p<0.001). Second trimester had greater abortion mortality than first trimester. Eastern region had greater abortion-related morbidity and mortality than Central region with facilities in the former characterised by inferior readiness to provide postabortion care. Uganda has a major abortion near-miss morbidity and mortality; with mortality higher in the second trimester. Life-saving commodities are lacking especially in Eastern region compromising facility readiness for postabortion care provision.

Identifiants

pubmed: 33547174
pii: bmjgh-2020-003274
doi: 10.1136/bmjgh-2020-003274
pmc: PMC7871269
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 107742/Z/15/Z
Pays : United Kingdom

Informations de copyright

© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Références

Lancet Glob Health. 2014 Jun;2(6):e323-33
pubmed: 25103301
Int J Gynaecol Obstet. 2012 Oct;119 Suppl 1:S68-71
pubmed: 22883917
Contraception. 2018 Mar 14;:
pubmed: 29550457
PLoS One. 2018 Feb 16;13(2):e0192438
pubmed: 29451883
BMC Pregnancy Childbirth. 2016 May 14;16:105
pubmed: 27180000
BMJ Glob Health. 2018 Jun 29;3(3):e000692
pubmed: 29989078
Trop Med Int Health. 2010 Aug;15(8):964-72
pubmed: 20636527
BMC Pregnancy Childbirth. 2017 Dec 29;17(1):445
pubmed: 29284433
BJOG. 2014 Mar;121 Suppl 1:25-31
pubmed: 24641532
Contraception. 2018 Dec;98(6):510-516
pubmed: 30217474
Lancet. 2018 Nov 10;392(10159):1995-2051
pubmed: 30496106
BMC Pregnancy Childbirth. 2015 Feb 15;15:34
pubmed: 25884662
PLoS One. 2012;7(12):e52090
pubmed: 23284882
BJOG. 2019 Jun;126 Suppl 3:33-40
pubmed: 31050874
Reprod Health. 2017 Oct 24;14(1):136
pubmed: 29065922
Lancet. 2017 Nov 25;390(10110):2372-2381
pubmed: 28964589
BMC Pregnancy Childbirth. 2016 Jan 28;16:24
pubmed: 26821716
Int J Gynaecol Obstet. 2015 Feb;128(2):160-4
pubmed: 25468057
Lancet. 2016 Jul 16;388(10041):258-67
pubmed: 27179755
Int Perspect Sex Reprod Health. 2018 Mar 1;44(1):1-9
pubmed: 30138102
BMC Health Serv Res. 2014 Jan 21;14:28
pubmed: 24447321
Br Med Bull. 2003;67:27-37
pubmed: 14711752
PLoS One. 2016 Nov 1;11(11):e0165812
pubmed: 27802338
Int J Gynaecol Obstet. 2019 Dec;147(3):389-396
pubmed: 31539164
Trop Med Int Health. 2012 Feb;17(2):177-90
pubmed: 22035193
BMC Pregnancy Childbirth. 2019 Feb 26;19(1):79
pubmed: 30808325
PLoS One. 2013 Apr 16;8(4):e61248
pubmed: 23613821
Best Pract Res Clin Obstet Gynaecol. 2009 Jun;23(3):287-96
pubmed: 19303368
J Obstet Gynaecol. 2018 Oct;38(7):961-966
pubmed: 29577786
BMC Womens Health. 2017 Dec 28;17(1):136
pubmed: 29282060
BMJ Open. 2018 Feb 10;8(2):e019658
pubmed: 29440163
PLoS One. 2011;6(6):e20776
pubmed: 21677788
Reprod Health. 2015 Oct 15;12:94
pubmed: 26470703
Lancet Glob Health. 2019 Jan;7(1):e110-e118
pubmed: 30503402
Contraception. 2017 Feb;95(2):167-174
pubmed: 27593334
Trials. 2017 Jul 6;18(1):307
pubmed: 28683806
Lancet. 2015 Jun 13;385(9985):2392-8
pubmed: 25817472

Auteurs

Susan Atuhairwe (S)

Department of Obstetrics and Gynaecology, Makerere University CHS, Kampala, Uganda atususan96@gmail.com.
Reproductive Endocrinology and Infertility, Mulago Specialised Women and Neonatal Hospital, Kampala, Uganda.

Kristina Gemzell-Danielsson (K)

Obstetrics and Gynecology, Women's and Children's Health, Stockholm, Sweden.

Josaphat Byamugisha (J)

Department of Obstetrics and Gynaecology, Makerere University CHS, Kampala, Uganda.

Frank Kaharuza (F)

Association of Obstetricians and Gynaecologists of Uganda, Kampala, Uganda.

Nazarius Mbona Tumwesigye (NM)

Epidemiology & Biostatistics, School of Public Health, Makerere University, Kampala, Uganda.

Claudia Hanson (C)

Public Health Sciences, Karolinska Institute, Stockholm, Sweden.
Dept of Disease Control, London School of Hygiene and Tropical Medicine Faculty of Infectious and Tropical Diseases, London, UK.

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Classifications MeSH