Whole-genome analyses of extended-spectrum or AmpC β-lactamase-producing Escherichia coli isolates from companion dogs in Japan.
Animals
Anti-Bacterial Agents
/ therapeutic use
Bacterial Proteins
/ genetics
Dogs
Enterobacteriaceae
/ drug effects
Enterobacteriaceae Infections
/ drug therapy
Escherichia coli
/ drug effects
Escherichia coli Infections
/ drug therapy
Extraintestinal Pathogenic Escherichia coli
/ drug effects
Humans
Japan
Microbial Sensitivity Tests
Plasmids
/ genetics
beta-Lactamases
/ genetics
Journal
PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081
Informations de publication
Date de publication:
2021
2021
Historique:
received:
13
11
2020
accepted:
19
01
2021
entrez:
5
2
2021
pubmed:
6
2
2021
medline:
31
7
2021
Statut:
epublish
Résumé
The emergence and global spread of extended-spectrum or AmpC β-lactamase (ESBL/AmpC)-producing Enterobacteriaceae in companion animals have led to the hypothesis that companion animals might be reservoirs for cross-species transmission because of their close contact with humans. However, current knowledge in this field is limited; therefore, the role of companion animals in cross-species transmission remains to be elucidated. Herein, we studied ESBL/AmpC-producing Enterobacteriaceae, Escherichia coli in particular, isolated from extraintestinal sites and feces of companion dogs. Whole-genome sequencing analysis revealed that (i) extraintestinal E. coli isolates were most closely related to those isolated from feces from the same dog, (ii) chromosomal sequences in the ST131/C1-M27 clade isolated from companion dogs were highly similar to those in the ST131/C1-M27 clade of human origin, (iii) certain plasmids, such as IncFII/pMLST F1:A2:B20/blaCTX-M-27, IncI1/pMLST16/blaCTX-M-15, or IncI1/blaCMY-2 from dog-derived E. coli isolates, shared high homology with those from several human-derived Enterobacteriaceae, (iv) chromosomal blaCTX-M-14 was identified in the ST38 isolate from a companion dog, and (v) eight out of 14 tested ESBL/AmpC-producing E. coli isolates (i.e., ST131, ST68, ST405, and ST998) belonged to the human extraintestinal pathogenic E. coli (ExPEC) group. All of the bla-coding plasmids that were sequenced genome-wide were capable of horizontal transfer. These results suggest that companion dogs can spread ESBL/AmpC-producing ExPEC via their feces. Furthermore, at least some ESBL/AmpC-producing ExPECs and bla-coding plasmids can be transmitted between humans and companion dogs. Thus, companion dogs can act as an important reservoir for ESBL/AmpC-producing E. coli in the community.
Identifiants
pubmed: 33544781
doi: 10.1371/journal.pone.0246482
pii: PONE-D-20-35693
pmc: PMC7864471
doi:
Substances chimiques
Anti-Bacterial Agents
0
Bacterial Proteins
0
AmpC beta-lactamases
EC 3.5.2.6
beta-Lactamases
EC 3.5.2.6
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0246482Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Microbiol Spectr. 2015 Oct;3(5):
pubmed: 26542041
PLoS One. 2014 Nov 19;9(11):e112963
pubmed: 25409509
Food Saf (Tokyo). 2017 Dec 29;5(4):122-150
pubmed: 32231938
BMC Genomics. 2018 Aug 9;19(1):601
pubmed: 30092762
Emerg Microbes Infect. 2019;8(1):1043-1053
pubmed: 31287781
Clin Microbiol Infect. 2013 Jul;19(7):E309-11
pubmed: 23581796
Antimicrob Agents Chemother. 2014 Aug;58(8):4949-52
pubmed: 24890591
Antimicrob Agents Chemother. 2015 Dec 07;60(2):982-9
pubmed: 26643327
Antimicrob Agents Chemother. 2010 Jul;54(7):3039-42
pubmed: 20421399
J Clin Microbiol. 2002 Jun;40(6):2153-62
pubmed: 12037080
Appl Environ Microbiol. 2016 Jul 15;82(15):4705-14
pubmed: 27235431
Curr Opin Microbiol. 2006 Oct;9(5):466-75
pubmed: 16942899
Lancet Infect Dis. 2013 Feb;13(2):155-65
pubmed: 23347633
Antibiotics (Basel). 2020 Jul 07;9(7):
pubmed: 32645942
J Med Microbiol. 2019 Mar;68(3):339-345
pubmed: 30698519
J Antimicrob Chemother. 2017 Aug 1;72(8):2145-2155
pubmed: 28541467
Antimicrob Agents Chemother. 2012 Jul;56(7):4013-7
pubmed: 22508313
Emerg Infect Dis. 2015 Jul;21(7):1247-50
pubmed: 26079171
Infect Immun. 2001 Mar;69(3):1306-14
pubmed: 11179292
Clin Microbiol Infect. 2012 Jul;18(7):646-55
pubmed: 22519858
Nucleic Acids Res. 2021 Jan 8;49(D1):D644-D650
pubmed: 33010178
J Clin Microbiol. 2013 Jan;51(1):232-7
pubmed: 23135946
Int J Antimicrob Agents. 2014 Dec;44(6):533-7
pubmed: 25446906
FEMS Microbiol Rev. 2017 May 1;41(3):252-275
pubmed: 28521338
J Antimicrob Chemother. 2020 Feb 1;75(2):342-350
pubmed: 31711228
J Glob Antimicrob Resist. 2019 Jun;17:53-57
pubmed: 30445208
Antimicrob Agents Chemother. 2016 Mar 25;60(4):2582-4
pubmed: 26810652
Microb Drug Resist. 2015 Dec;21(6):643-50
pubmed: 26098354
Proc Natl Acad Sci U S A. 1978 Aug;75(8):3737-41
pubmed: 358200
PLoS Genet. 2014 Dec 18;10(12):e1004776
pubmed: 25522320
Euro Surveill. 2018 Jul;23(27):
pubmed: 29991384
Biosci Microbiota Food Health. 2016;35(4):173-184
pubmed: 27867804
Antimicrob Agents Chemother. 2018 Sep 24;62(10):
pubmed: 30012771
J Infect Dis. 2008 Jan 15;197(2):218-24
pubmed: 18179385
J Antimicrob Chemother. 2012 Nov;67(11):2640-4
pubmed: 22782487
J Antimicrob Chemother. 2021 Jan 1;76(1):101-109
pubmed: 33009809
Nucleic Acids Res. 1983 Sep 24;11(18):6319-30
pubmed: 6312419
Plasmid. 2000 Jul;44(1):66-84
pubmed: 10873528
Proc Natl Acad Sci U S A. 2011 Dec 13;108(50):20142-7
pubmed: 22135463
Proc Natl Acad Sci U S A. 1987 Nov;84(22):8049-53
pubmed: 2825175
Antimicrob Agents Chemother. 2015 Aug;59(8):5000-2
pubmed: 25987637
Front Microbiol. 2020 Jul 24;11:1610
pubmed: 32793144
Clin Microbiol Infect. 2008 Jan;14 Suppl 1:144-53
pubmed: 18154538
PLoS Comput Biol. 2017 Jun 8;13(6):e1005595
pubmed: 28594827
Antimicrob Agents Chemother. 2016 Jun 20;60(7):4073-81
pubmed: 27114279
Antimicrob Agents Chemother. 2019 Jun 24;63(7):
pubmed: 31085509
Int J Food Microbiol. 2018 Nov 2;284:98-104
pubmed: 30096596
Lancet Infect Dis. 2008 Mar;8(3):159-66
pubmed: 18291338
Clin Microbiol Infect. 2014 May;20(5):380-90
pubmed: 24766445
Nat Biotechnol. 2019 May;37(5):540-546
pubmed: 30936562
FEMS Immunol Med Microbiol. 2011 Jun;62(1):1-10
pubmed: 21362060
F1000Res. 2017 Feb 28;6:
pubmed: 28344773
Microbiol Immunol. 1994;38(1):31-8
pubmed: 8052160
Front Microbiol. 2019 Dec 10;10:2852
pubmed: 31921034
PLoS One. 2020 Jan 13;15(1):e0227605
pubmed: 31929575
J Clin Microbiol. 2015 Aug;53(8):2410-26
pubmed: 25972421
BMC Genomics. 2008 Feb 08;9:75
pubmed: 18261238
Emerg Infect Dis. 2017 May;23(5):885
pubmed: 28418829
Proc Natl Acad Sci U S A. 2019 Jul 16;116(29):14740-14748
pubmed: 31262826
mSphere. 2016 Jun 29;1(4):
pubmed: 27390780
Clin Microbiol Rev. 2009 Jan;22(1):161-82, Table of Contents
pubmed: 19136439
J Clin Microbiol. 2017 Aug;55(8):2538-2543
pubmed: 28592545
Antimicrob Agents Chemother. 2006 Feb;50(2):791-5
pubmed: 16436748
J Antimicrob Chemother. 2015;70(6):1639-49
pubmed: 25687644
Nucleic Acids Res. 2016 Jul 8;44(W1):W16-21
pubmed: 27141966
Int J Antimicrob Agents. 2013 Dec;42(6):500-6
pubmed: 24091130
Lancet. 2004 Apr 17;363(9417):1285-6
pubmed: 15094275
Front Microbiol. 2015 Aug 18;6:831
pubmed: 26347723
Antimicrob Agents Chemother. 2009 Sep;53(9):4002-6
pubmed: 19596889
Infection. 2019 Jun;47(3):363-375
pubmed: 30840201
Comp Immunol Microbiol Infect Dis. 2012 Mar;35(2):139-44
pubmed: 22252047
Plasmid. 2018 Dec 5;:
pubmed: 30529488
J Mol Evol. 1997 Jan;44(1):57-65
pubmed: 9010136
Antimicrob Agents Chemother. 2003 Jul;47(7):2161-8
pubmed: 12821463
Microbes Infect. 2003 Apr;5(5):449-56
pubmed: 12738001
J Antimicrob Chemother. 2006 Jan;57(1):14-23
pubmed: 16291869
Antimicrob Agents Chemother. 2014 Jul;58(7):3895-903
pubmed: 24777092
Vet Microbiol. 2018 Mar;216:183-189
pubmed: 29519514
Plasmid. 2011 Sep;66(3):144-51
pubmed: 21843549
J Antimicrob Chemother. 2011 Oct;66(10):2263-5
pubmed: 21795257
J Antimicrob Chemother. 2006 Mar;57(3):424-9
pubmed: 16396917
Clin Infect Dis. 2006 Nov 15;43(10):e101-8
pubmed: 17051483
J Antimicrob Chemother. 2017 Apr 1;72(4):957-968
pubmed: 27999066
FEMS Microbiol Lett. 2003 Mar 28;220(2):177-80
pubmed: 12670678
FEMS Microbiol Lett. 2000 Mar 1;184(1):53-6
pubmed: 10689165
Front Microbiol. 2018 Jul 10;9:1482
pubmed: 30042741
Int J Antimicrob Agents. 2014 Sep;44(3):203-8
pubmed: 25052868
Antimicrob Agents Chemother. 2017 Mar 24;61(4):
pubmed: 28167556
Appl Environ Microbiol. 2020 Nov 24;86(24):
pubmed: 33036993
Appl Environ Microbiol. 2009 Sep;75(18):5963-71
pubmed: 19648374
Emerg Infect Dis. 2017 Oct;23(10):1754-1756
pubmed: 28930021
J Clin Microbiol. 2005 Jun;43(6):2551-8
pubmed: 15956362
Antimicrob Agents Chemother. 2012 Feb;56(2):1093-6
pubmed: 22106217
PLoS One. 2014 Aug 11;9(8):e104984
pubmed: 25110940
Front Microbiol. 2020 Apr 15;11:674
pubmed: 32351490
J Antibiot (Tokyo). 2019 Feb;72(2):79-85
pubmed: 30361635
J Antimicrob Chemother. 2004 Aug;54(2):321-32
pubmed: 15254022
Mol Microbiol. 2006 Jun;60(5):1136-51
pubmed: 16689791
J Clin Microbiol. 2014 May;52(5):1501-10
pubmed: 24574290
J Clin Microbiol. 2006 Aug;44(8):2831-7
pubmed: 16891499
J Infect Dis. 2000 May;181(5):1753-4
pubmed: 10823778
BMC Vet Res. 2012 Mar 07;8:21
pubmed: 22397509
PLoS One. 2017 Jan 26;12(1):e0170777
pubmed: 28125687
Clin Infect Dis. 2007 Sep 1;45 Suppl 2:S148-52
pubmed: 17683019
J Clin Microbiol. 2000 Jan;38(1):40-3
pubmed: 10618060
Diagn Microbiol Infect Dis. 2017 Jan;87(1):64-67
pubmed: 27773543
Microb Genom. 2019 Sep;5(9):
pubmed: 31486766
Microbiol Spectr. 2015 Aug;3(4):
pubmed: 26350313
Antimicrob Agents Chemother. 2018 Sep 24;62(10):
pubmed: 30061277
Infect Drug Resist. 2015 Apr 01;8:49-61
pubmed: 25878509
PLoS One. 2010 Jun 18;5(6):e11202
pubmed: 20585456
Mol Gen Genet. 1984;198(2):84-9
pubmed: 6097800
PLoS One. 2018 Feb 6;13(2):e0192504
pubmed: 29408896
Bioinformatics. 2011 Apr 1;27(7):1009-10
pubmed: 21278367
Microbiology (Reading). 2015 May;161(Pt 5):980-988
pubmed: 25714816
Emerg Infect Dis. 2016 Nov;22(11):1900-1907
pubmed: 27767006