Jugular Vein Thrombosis and Anticoagulation Therapy in Lemierre's Syndrome
Fusobacterium necrophorum
Lemierre
Lemierre’s syndrome
jugular thrombosis
septic thrombophlebitis
Journal
Open forum infectious diseases
ISSN: 2328-8957
Titre abrégé: Open Forum Infect Dis
Pays: United States
ID NLM: 101637045
Informations de publication
Date de publication:
Jan 2021
Jan 2021
Historique:
received:
03
11
2020
accepted:
25
11
2020
entrez:
15
1
2021
pubmed:
16
1
2021
medline:
16
1
2021
Statut:
epublish
Résumé
Lemierre's syndrome is typically caused by Patients with invasive infection with Fifty-one of 82 (62%) radiologically investigated patients with Lemierre's syndrome had jugular vein thrombosis. Patients with jugular vein thrombosis had lower platelet levels (median, 76 vs 112 ×10 Patients with Lemierre's syndrome with jugular vein thrombosis were more severely affected, yet had similar prognosis. Most patients with jugular vein thrombosis recovered well without therapeutic anticoagulation therapy, though adverse events were similarly rare in anticoagulated patients. The observational design and rarity of study outcomes require cautious interpretation.
Sections du résumé
BACKGROUND
BACKGROUND
Lemierre's syndrome is typically caused by
METHODS
METHODS
Patients with invasive infection with
RESULTS
RESULTS
Fifty-one of 82 (62%) radiologically investigated patients with Lemierre's syndrome had jugular vein thrombosis. Patients with jugular vein thrombosis had lower platelet levels (median, 76 vs 112 ×10
CONCLUSIONS
CONCLUSIONS
Patients with Lemierre's syndrome with jugular vein thrombosis were more severely affected, yet had similar prognosis. Most patients with jugular vein thrombosis recovered well without therapeutic anticoagulation therapy, though adverse events were similarly rare in anticoagulated patients. The observational design and rarity of study outcomes require cautious interpretation.
Identifiants
pubmed: 33447643
doi: 10.1093/ofid/ofaa585
pii: ofaa585
pmc: PMC7793455
doi:
Types de publication
Journal Article
Langues
eng
Pagination
ofaa585Informations de copyright
© The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America.
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