Sustainable Triazine-Based Dehydro-Condensation Agents for Amide Synthesis.
Amides
/ chemical synthesis
Amines
/ chemistry
Benzamides
/ chemical synthesis
Carboxylic Acids
/ chemistry
Chemistry Techniques, Synthetic
/ methods
Perchlorates
/ chemistry
Phenethylamines
/ chemical synthesis
Piperazines
/ chemistry
Quaternary Ammonium Compounds
/ chemistry
Solvents
/ chemistry
Triazines
/ chemistry
CDMT
amide synthesis
sustainable dehydro-condensation agents
triazines
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
02 Jan 2021
02 Jan 2021
Historique:
received:
08
12
2020
revised:
22
12
2020
accepted:
29
12
2020
entrez:
6
1
2021
pubmed:
7
1
2021
medline:
4
9
2021
Statut:
epublish
Résumé
Conventional methods employed today for the synthesis of amides often lack of economic and environmental sustainability. Triazine-derived quaternary ammonium salts, e.g., 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride (DMTMM(Cl)), emerged as promising dehydro-condensation agents for amide synthesis, although suffering of limited stability and high costs. In the present work, a simple protocol for the synthesis of amides mediated by 2-chloro-4,6-dimethoxy-1,3,5-triazine (CDMT) and a
Identifiants
pubmed: 33401732
pii: molecules26010191
doi: 10.3390/molecules26010191
pmc: PMC7795458
pii:
doi:
Substances chimiques
Amides
0
Amines
0
Benzamides
0
Carboxylic Acids
0
N-phenethylbenzamide
0
Perchlorates
0
Phenethylamines
0
Piperazines
0
Quaternary Ammonium Compounds
0
Solvents
0
Triazines
0
1,4-dimethylpiperazine
TF146U602L
perchlorate
VLA4NZX2P4
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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