Severe infections in neurocritical care.
Journal
Current opinion in critical care
ISSN: 1531-7072
Titre abrégé: Curr Opin Crit Care
Pays: United States
ID NLM: 9504454
Informations de publication
Date de publication:
01 04 2021
01 04 2021
Historique:
pubmed:
5
1
2021
medline:
24
4
2021
entrez:
4
1
2021
Statut:
ppublish
Résumé
We have highlighted the recent advances in infection in neurocritical care. Central nervous system (CNS) infections, including meningitis, encephalitis and pyogenic brain infections represent a significant cause of ICU admissions. We underwent an extensive review of the literature over the last several years in order to summarize the most important points in the diagnosis and treatment of severe infections in neurocritical care. Acute brain injury triggers an inflammatory response that involves a complex interaction between innate and adaptive immunity, and there are several factors that can be implicated, such as age, genetic predisposition, the degree and mechanism of the injury, systemic and secondary injury and therapeutic interventions. Neuroinflammation is a major contributor to secondary injury. The frequent and challenging presence of fever is a common denominator amongst all neurocritical care patients.
Identifiants
pubmed: 33395081
doi: 10.1097/MCC.0000000000000796
pii: 00075198-202104000-00009
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
131-138Informations de copyright
Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.
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