Effects of COVID-19 Home Confinement on Mental Health in Individuals with Increased Risk of Alzheimer's Disease.
Aged
Aged, 80 and over
Alzheimer Disease
/ diagnosis
Anxiety Disorders
/ diagnosis
Apolipoprotein E3
/ genetics
Apolipoprotein E4
/ genetics
COVID-19
/ genetics
Cognition Disorders
/ diagnosis
Cognitive Dysfunction
/ diagnosis
Depressive Disorder
/ diagnosis
Female
Humans
Male
Mental Health
Middle Aged
Psychological Distress
Quarantine
/ psychology
Risk
Spain
Alzheimer’s disease
COVID-19
confinement
mental health
subjective
cognitive decline
Journal
Journal of Alzheimer's disease : JAD
ISSN: 1875-8908
Titre abrégé: J Alzheimers Dis
Pays: Netherlands
ID NLM: 9814863
Informations de publication
Date de publication:
2021
2021
Historique:
pubmed:
3
1
2021
medline:
16
2
2021
entrez:
2
1
2021
Statut:
ppublish
Résumé
We explored the impact of the Spanish COVID-19 strict home confinement on mental health and cognition in non-infected subjects (N = 16, 60-80 years) diagnosed with subjective cognitive decline and APOEɛ3/ɛ4 carriers. Mental health was monitored for 2 months on a daily, weekly, or monthly basis, and compared to pre-confinement values. Emotional distress, anxiety, and depression scores increased to pathological threshold values during and after confinement. Those with lower mood during confinement experienced a decline in their mood after confinement. Cognition did not change. These preliminary results suggest that mental health consequences of corona measures in preclinical stages of Alzheimer's disease should be further evaluated.
Identifiants
pubmed: 33386809
pii: JAD201408
doi: 10.3233/JAD-201408
pmc: PMC7990405
doi:
Substances chimiques
Apolipoprotein E3
0
Apolipoprotein E4
0
Types de publication
Letter
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1015-1021Investigateurs
Rafael de la Torre
(R)
Laura Forcano
(L)
Neus Pizarro
(N)
Albert Puig-Pijoan
(A)
Natalia Soldevila-Domenech
(N)
Anna Boronat
(A)
Thais Lorenzo
(T)
Aida Cuenca
(A)
Julian Mateus
(J)
Iris Piera
(I)
Ana Aldea
(A)
Patricia Diaz-Pellicer
(P)
Mara Dierssen
(M)
Maria Gomis
(M)
Jose Luis Molinuevo
(JL)
Iva Knezevic
(I)
Sofia Menezes-Cabral
(S)
Anna Soteras
(A)
José Maria González-de-Echávarri
(JM)
Gonzalo Sánchez-Benavides
(G)
Juan Domingo Gispert
(JD)
Karine Fauria
(K)
Carolina Minguillón
(C)
Références
Front Psychiatry. 2020 Oct 14;11:578628
pubmed: 33173523
Front Nutr. 2019 Jul 23;6:110
pubmed: 31396517
Acta Psychiatr Scand. 1983 Jun;67(6):361-70
pubmed: 6880820
Int J Behav Dev. 2009;33(6):565-576
pubmed: 23885133
Neuropsychiatr Dis Treat. 2017 Feb 16;13:491-498
pubmed: 28243102
Educ Psychol Meas. 2016 Feb;76(1):64-87
pubmed: 29795857
Front Psychiatry. 2020 Oct 26;11:585686
pubmed: 33192733
Lancet. 2020 Mar 14;395(10227):912-920
pubmed: 32112714
Rev Neurol. 2016 Dec 1;63(11):488-496
pubmed: 27874165
JMIR Mhealth Uhealth. 2017 Apr 12;5(4):e44
pubmed: 28404542
Lancet Neurol. 2020 Mar;19(3):271-278
pubmed: 31958406
Gerontologist. 2016 Dec;56(6):e109-e127
pubmed: 27342440
Alzheimers Dement. 2020 Jul;16(7):1078-1094
pubmed: 32627328
Clin Neuropsychol. 2015;29(6):824-35
pubmed: 26373627
J Epidemiol Community Health. 2021 Mar;75(3):224-231
pubmed: 32978210
Psychol Med. 1997 Jan;27(1):191-7
pubmed: 9122299