Investigation on the Interactions between Self-Assembled β-Sheet Peptide Nanofibers and Model Cell Membranes.
DPPC Langmuir membrane
drug delivery system
nanofiber
π–A isotherm
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
14 Dec 2020
14 Dec 2020
Historique:
received:
11
11
2020
revised:
10
12
2020
accepted:
12
12
2020
entrez:
17
12
2020
pubmed:
18
12
2020
medline:
16
3
2021
Statut:
epublish
Résumé
Self-assembled peptide nanofibers (NFs) obtained from β-sheet peptides conjugated with drugs, including antigenic peptides, have recently attracted significant attention. However, extensive studies on the interactions of β-sheet peptide NFs with model cell membranes have not been reported. In this study, we investigated the interactions between three types of NFs, composed of PEG-peptide conjugates with different ethylene glycol (EG) lengths (6-, 12- and 24-mer), and dipalmitoylphosphatidylcholine (DPPC) Langmuir membranes. When increasing the EG chain length, those interactions significantly decreased considering measurements in the presence of the NFs of: (i) changes in surface pressure of the DPPC Langmuir monolayers and (ii) surface pressure-area (π-
Identifiants
pubmed: 33327660
pii: ijms21249518
doi: 10.3390/ijms21249518
pmc: PMC7765088
pii:
doi:
Substances chimiques
Membranes, Artificial
0
Ethylene Glycol
FC72KVT52F
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Japan Society for the Promotion of Science
ID : 19K12800
Références
Int J Mol Sci. 2019 Aug 02;20(15):
pubmed: 31382455
ACS Appl Mater Interfaces. 2013 Dec 26;5(24):13063-8
pubmed: 24295326
Small. 2010 Jan;6(1):12-21
pubmed: 19844908
Biophys J. 2006 Jun 15;90(12):4488-99
pubmed: 16581831
Mol Pharm. 2008 May-Jun;5(3):418-29
pubmed: 18271547
Langmuir. 2006 Jun 6;22(12):5341-9
pubmed: 16732662
Langmuir. 2017 Oct 10;33(40):10715-10725
pubmed: 28926262
Proc Natl Acad Sci U S A. 1986 Jan;83(2):503-7
pubmed: 3455785
J Phys Chem B. 2006 Nov 23;110(46):23292-9
pubmed: 17107178
Colloids Surf B Biointerfaces. 2006 Dec 1;53(2):179-86
pubmed: 17046216
J Mater Chem B. 2020 Feb 14;8(6):1093-1107
pubmed: 31960007
Nat Mater. 2009 Jul;8(7):543-57
pubmed: 19525947
Langmuir. 2006 Aug 29;22(18):7701-11
pubmed: 16922553
Langmuir. 2020 May 5;36(17):4808-4819
pubmed: 32306733
Langmuir. 2005 Jun 7;21(12):5475-84
pubmed: 15924478
J Am Chem Soc. 2013 Feb 27;135(8):2907-10
pubmed: 23379791
Langmuir. 2009 Feb 17;25(4):2369-77
pubmed: 19161268
Langmuir. 2006 Jan 31;22(3):1182-92
pubmed: 16430282
Mol Pharm. 2009 Sep-Oct;6(5):1311-20
pubmed: 19243206
Bioconjug Chem. 2006 May-Jun;17(3):728-34
pubmed: 16704211
Adv Drug Deliv Rev. 2017 Feb;110-111:112-126
pubmed: 27370248
Langmuir. 2009 Nov 17;25(22):12968-73
pubmed: 19739623
Langmuir. 2007 Feb 27;23(5):2631-7
pubmed: 17309214
Langmuir. 2006 Jul 4;22(14):6293-301
pubmed: 16800689
J R Soc Interface. 2009 Jun 6;6 Suppl 3:S325-39
pubmed: 19364722
Langmuir. 2007 Dec 4;23(25):12617-23
pubmed: 17973510
Science. 2004 Mar 19;303(5665):1818-22
pubmed: 15031496
Colloids Surf B Biointerfaces. 2013 Aug 1;108:120-6
pubmed: 23528608
J Control Release. 2001 Jan 29;70(1-2):1-20
pubmed: 11166403
Langmuir. 2005 Nov 8;21(23):10348-54
pubmed: 16262291
Acc Chem Res. 2013 Mar 19;46(3):622-31
pubmed: 22891796
Langmuir. 2010 Nov 16;26(22):17256-9
pubmed: 20964299
Biochim Biophys Acta Biomembr. 2019 Oct 1;1861(10):182994
pubmed: 31145899
Chemistry. 2015 Jan 2;21(1):101-5
pubmed: 25384556
Chem Rev. 2014 Aug 13;114(15):7740-81
pubmed: 24927254