Cortical tension overrides geometrical cues to orient microtubules in confined protoplasts.


Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
22 12 2020
Historique:
pubmed: 9 12 2020
medline: 20 2 2021
entrez: 8 12 2020
Statut: ppublish

Résumé

In plant cells, cortical microtubules (CMTs) generally control morphogenesis by guiding cellulose synthesis. CMT alignment has been proposed to depend on geometrical cues, with microtubules aligning with the cell long axis in silico and in vitro. Yet, CMTs are usually transverse in vivo, i.e., along predicted maximal tension, which is transverse for cylindrical pressurized vessels. Here, we adapted a microwell setup to test these predictions in a single-cell system. We confined protoplasts laterally to impose a curvature ratio and modulated pressurization through osmotic changes. We find that CMTs can be longitudinal or transverse in wallless protoplasts and that the switch in CMT orientation depends on pressurization. In particular, longitudinal CMTs become transverse when cortical tension increases. This explains the dual behavior of CMTs in planta: CMTs become longitudinal when stress levels become low, while stable transverse CMT alignments in tissues result from their autonomous response to tensile stress fluctuations.

Identifiants

pubmed: 33288703
pii: 2008895117
doi: 10.1073/pnas.2008895117
pmc: PMC7768696
doi:

Substances chimiques

Poloxamer 106392-12-5
Green Fluorescent Proteins 147336-22-9

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

32731-32738

Informations de copyright

Copyright © 2020 the Author(s). Published by PNAS.

Déclaration de conflit d'intérêts

The authors declare no competing interest.

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Auteurs

Leia Colin (L)

Laboratoire de Reproduction et Développement des Plantes, Université de Lyon, ENS de Lyon, UCBL, INRAE, CNRS, 69364 Lyon Cedex 07, France.

Antoine Chevallier (A)

Laboratoire de Reproduction et Développement des Plantes, Université de Lyon, ENS de Lyon, UCBL, INRAE, CNRS, 69364 Lyon Cedex 07, France.
Mechanobiology Institute, National University of Singapore, 117411 Singapore, Singapore.

Satoru Tsugawa (S)

Division of Biological Science, Graduate School of Science and Technology, Nara Institute of Science and Technology, Nara 630-0192, Japan.

Florian Gacon (F)

Laboratoire de Reproduction et Développement des Plantes, Université de Lyon, ENS de Lyon, UCBL, INRAE, CNRS, 69364 Lyon Cedex 07, France.

Christophe Godin (C)

Laboratoire de Reproduction et Développement des Plantes, Université de Lyon, ENS de Lyon, UCBL, INRAE, CNRS, 69364 Lyon Cedex 07, France.

Virgile Viasnoff (V)

Mechanobiology Institute, National University of Singapore, 117411 Singapore, Singapore.
Department of Biological Sciences, National University of Singapore, 117558 Singapore, Singapore.
Centre National pour la Recherche Scientifique, UMI 3639, 117411 Singapore, Singapore.

Timothy E Saunders (TE)

Mechanobiology Institute, National University of Singapore, 117411 Singapore, Singapore.
Department of Biological Sciences, National University of Singapore, 117558 Singapore, Singapore.

Olivier Hamant (O)

Laboratoire de Reproduction et Développement des Plantes, Université de Lyon, ENS de Lyon, UCBL, INRAE, CNRS, 69364 Lyon Cedex 07, France; olivier.hamant@ens-lyon.fr.

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