Use of Anti-Dementia Drugs Reduces the Risk of Potentially Inappropriate Medications: A Secondary Analysis of a Nationwide Survey of Prescribing Pharmacies.
Aged
Dementia
/ drug therapy
Drug Prescriptions
/ standards
Female
Humans
Inappropriate Prescribing
/ prevention & control
Japan
/ epidemiology
Male
Nootropic Agents
/ therapeutic use
Potentially Inappropriate Medication List
Practice Patterns, Physicians'
/ statistics & numerical data
Psychotropic Drugs
/ therapeutic use
Surveys and Questionnaires
Anti-dementia drugs
Nationwide survey
Potentially inappropriate medications
Prescribing pharmacies
Journal
Dementia and geriatric cognitive disorders
ISSN: 1421-9824
Titre abrégé: Dement Geriatr Cogn Disord
Pays: Switzerland
ID NLM: 9705200
Informations de publication
Date de publication:
2020
2020
Historique:
received:
05
09
2020
accepted:
30
09
2020
pubmed:
7
12
2020
medline:
16
6
2021
entrez:
6
12
2020
Statut:
ppublish
Résumé
As the number of older people with dementia increases, safe pharmacotherapy in this population has attracted attention in recent years. The aims of this study were to clarify the prescribing patterns in older patients who were prescribed anti-dementia drugs and to investigate the association of potentially inappropriate medications (PIMs) with the use of anti-dementia drugs. Adults aged ≥65 years, who were prescribed anti-dementia drugs at 585 pharmacies across Japan (N = 7,953), were surveyed. The percentage of prescriptions of anti-dementia drugs and the effect of those prescriptions on PIMs were investigated. Prescriptions of anti-dementia drugs were found in 4.4% of the entire study population. A multiple logistic regression analysis revealed that the use of anti-dementia drugs reduced the risk of prescribing psychotropic drugs, which represented PIMs, and that a combination of anti-dementia drugs (e.g., cholineesterase inhibitor with memantine) may reduce the risk of prescribing PIMs compared with monotherapy. The use of anti-dementia drugs was associated with fewer prescriptions of drugs considered as PIMs.
Identifiants
pubmed: 33279893
pii: 000512043
doi: 10.1159/000512043
pmc: PMC7949214
doi:
Substances chimiques
Nootropic Agents
0
Psychotropic Drugs
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
526-532Informations de copyright
The Author(s). Published by S. Karger AG, Basel.
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