Efficacy of Botulinum Toxin in Treating Lateral Epicondylitis-Does Injection Location Matter?: A Systematic Review.
Journal
American journal of physical medicine & rehabilitation
ISSN: 1537-7385
Titre abrégé: Am J Phys Med Rehabil
Pays: United States
ID NLM: 8803677
Informations de publication
Date de publication:
12 2020
12 2020
Historique:
entrez:
20
11
2020
pubmed:
21
11
2020
medline:
31
12
2020
Statut:
ppublish
Résumé
Clinical trials assessing the efficacy of botulinum toxin in treating recalcitrant lateral epicondylitis have demonstrated varied results and differed greatly in methodology. The objective of this systematic review was to demonstrate injection location as a significant contributor to outcome heterogeneity. Two reviewers independently conducted a systematic review using Scopus, Embase, and PubMed for randomized controlled trials assessing botulinum toxin in the treatment of lateral epicondylitis. After applying inclusion/exclusion criteria to abstracts and reviewing the full-text articles, seven studies were found representing six separate injection locations. Reduction in visual analog scale pain and change in grip strength were the principal outcomes of interest. The largest reduction in pain was seen in injection at 1/3 of the length of the forearm from the lateral epicondyle at 16-wk follow-up, whereas the smallest reduction was seen at 12-wk follow-up after injection at the 0-cm mark. Differences were also identified in grip strength, although all studies reported return to baseline strength by weeks 12-18. This study demonstrates injection location as a potential source of heterogeneity. This clinical question warrants further evaluation with direct comparison of outcomes at different injection locations while controlling for dosage, toxin type, and ultrasound/electromyographic guidance.
Identifiants
pubmed: 33214499
doi: 10.1097/PHM.0000000000001511
pii: 00002060-202012000-00013
doi:
Substances chimiques
Neuromuscular Agents
0
Botulinum Toxins, Type A
EC 3.4.24.69
Types de publication
Journal Article
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1157-1163Commentaires et corrections
Type : CommentIn
Références
Nirschl RP, Ashman ES: Elbow tendinopathy: tennis elbow. Clin Sports Med 2003;22:813–36
Shiri R, Viikari-Juntura E, Varonen H, et al.: Prevalence and determinants of lateral and medial epicondylitis: a population study. Am J Epidemiol 2006;164:1065–74
Krogh TP, Bartels EM, Ellingsen T, et al.: Comparative effectiveness of injection therapies in lateral epicondylitis. Am J Sports Med 2012;41:1435–46
Walker-Bone K, Palmer KT, Reading I, et al.: Prevalence and impact of musculoskeletal disorders of the upper limb in the general population. Arthritis Care Res 2004;51:642–51
Degen RM, Conti MS, Camp CL, et al.: Epidemiology and disease burden of lateral epicondylitis in the USA: analysis of 85,318 patients. HSS J 2017;14:9–14
Sanders TL Jr., Maradit Kremers H, Bryan AJ, et al.: The epidemiology and health care burden of tennis elbow. Am J Sports Med 2015;43:1066–71
Smidt N, van der Windt DA, Assendelft WJ, et al.: Corticosteroid injections, physiotherapy, or a wait-and-see policy for lateral epicondylitis: a randomised controlled trial. The Lancet 2002;359:657–62
Bhabra G, Wang A, Ebert JR, et al.: Lateral elbow tendinopathy. Orthop J Sports Med 2016;4:192596711667063
Mattie R, Wong J, McCormick Z, et al.: Percutaneous needle tenotomy for the treatment of lateral epicondylitis: a systematic review of the literature. PM R 2017;9:603–11
Placzek R, Drescher W, Deuretzbacher G, et al.: Treatment of chronic radial epicondylitis with botulinum toxin A. J Bone Joint Surg Am 2007;89:255–60
Coombes BK, Bisset L, Brooks P, et al.: Effect of corticosteroid injection, physiotherapy, or both on clinical outcomes in patients with unilateral lateral epicondylalgia. JAMA 2013;239:461
Bisset L, Beller E, Jull G, et al.: Mobilisation with movement and exercise, corticosteroid injection, or wait and see for tennis elbow: randomised trial. BMJ 2006;333:939
Houck DA, Kraeutler MJ, Thornton LB, et al.: Treatment of lateral epicondylitis with autologous blood, platelet-rich plasma, or corticosteroid injections: a systematic review of overlapping meta-analyses. Orthop J Sports Med 2019;7:192596711983105
Espandar R, Heidari P, Rasouli MR, et al.: Use of anatomic measurement to guide injection of botulinum toxin for the management of chronic lateral epicondylitis: a randomized controlled trial. CMAJ 2010;182:768–73
Guo YH, Kuan TS, Chen KL, et al.: Comparison between steroid and 2 different sites of botulinum toxin injection in the treatment of lateral epicondylalgia: a randomized, double-blind, active drug-controlled pilot study. Arch Phys Med Rehabil 2017;98:36–42
Hayton MJ, Santini AJA, Hughes PJ, et al.: Botulinum toxin injection in the treatment of tennis elbow. J Bone Joint Surg Am 2005;87:503–7
Judson CH, Wolf JM: Lateral epicondylitis: review of injection therapies. Orthop Clin North Am 2013;44:615–23
Morre HH, Keizer SB, van Os JJ: Treatment of chronic tennis elbow with botulinum toxin. Lancet 1997;349:1746
Keizer SB, Rutten HP, Pilot P, et al.: Botulinum toxin injection versus surgical treatment for tennis elbow: a randomized pilot study. Clin Orthop 2002;401:125–31
Cogné M, Creuzé A, Petit H, et al.: Number of botulinum toxin injections needed to stop requests for treatment for chronic lateral epicondylar tendinopathy. A 1-year follow-up study. Ann Phys Rehabil Med 2019;62:336–41
Lin YC, Tu YK, Chen SS, et al.: Comparison between botulinum toxin and corticosteroid injection in the treatment of acute and subacute tennis elbow. Am J Phys Med Rehabil 2010;89:653–9
Wong SM, Hui ACF, Tong PY, et al.: Treatment of lateral epicondylitis with botulinum toxin. Ann Intern Med 2005;143:793–7
Lin YC, Wu WT, Hsu YC, et al.: Comparative effectiveness of botulinum toxin versus non-surgical treatments for treating lateral epicondylitis: a systematic review and meta-analysis. Clin Rehabil 2017;32:131–45
Creuzé A, Petit H, de Sèze M: Short-term effect of low-dose, electromyography-guided botulinum toxin A injection in the treatment of chronic lateral epicondylar tendinopathy. J Bone Joint Surg Am 2018;100:818–26
Myles PS, Myles DB, Galagher W, et al.: Measuring acute postoperative pain using the visual analog scale: the minimal clinically important difference and patient acceptable symptom state. Br J Anaesth 2017;118:424–9
Knobloch K, Spies M, Vogt PM: Adverse effects of intratendinous injection. AJR Am J Roentgenol 2008;190:W316–6
Lee SH, Choi HH, Chang MC: The effect of botulinum toxin injection into the common extensor tendon in patients with chronic lateral epicondylitis: a randomized trial. Pain Med 2020;21:1971–6
Kalichman L, Bannuru RR, Severin M, et al.: Injection of botulinum toxin for treatment of chronic lateral epicondylitis: systematic review and meta-analysis. Semin Arthritis Rheum 2011;40:532–8
Roze S, Kurth H, Hunt B, et al.: Evaluation of the cost per patient per injection of botulinum toxin A in upper limb spasticity: comparison of two preparations in 19 countries. Med Devices (Auckl) 2012;5:97–101