Increased incidence of and microbiologic changes in pyogenic liver abscesses in the Mexican population.
Complications
Epidemiology
Liver abscess
Mexican population
Mortality
Outcomes
Pyogenic
Journal
World journal of hepatology
ISSN: 1948-5182
Titre abrégé: World J Hepatol
Pays: United States
ID NLM: 101532469
Informations de publication
Date de publication:
27 Oct 2020
27 Oct 2020
Historique:
received:
25
05
2020
revised:
26
06
2020
accepted:
16
08
2020
entrez:
17
11
2020
pubmed:
18
11
2020
medline:
18
11
2020
Statut:
ppublish
Résumé
Pyogenic liver abscess (PLA) is a rare disease with an estimated incidence that varies widely across the globe, being as high as 115.4/100000 habitants in Taiwan and as low as 1.1-1.2/100000 habitants in Europe and Canada. Even though there are multiple microorganisms capable of producing an abscess in the liver, including To describe the clinical, demographic and microbiologic characteristics of PLA in Mexico. This is a retrospective study carried out in two centers, and included patients seen between 2006 and 2018 with the diagnosis of pyogenic abscess. We collected demographic, clinical, and microbiological information, treatment, complications, and outcomes. A logistic regression analysis was used to determine the association between different variables and mortality rates. A total of 345 patients were included in this study. 233 (67.5%) had confirmed PLA, 133 (30%) patients had no positive culture and negative serology and 9 (2.5%) had mixed abscesses. The mean age was 50 years (ranging from 16-97 years) and 63% were female. 65% of the patients had positive cultures for Extended Spectrum Beta-Lactamases (ESBL)- The prevalence of PLA is increasing in Mexico and has a very high mortality rate. ESBL-
Sections du résumé
BACKGROUND
BACKGROUND
Pyogenic liver abscess (PLA) is a rare disease with an estimated incidence that varies widely across the globe, being as high as 115.4/100000 habitants in Taiwan and as low as 1.1-1.2/100000 habitants in Europe and Canada. Even though there are multiple microorganisms capable of producing an abscess in the liver, including
AIM
OBJECTIVE
To describe the clinical, demographic and microbiologic characteristics of PLA in Mexico.
METHODS
METHODS
This is a retrospective study carried out in two centers, and included patients seen between 2006 and 2018 with the diagnosis of pyogenic abscess. We collected demographic, clinical, and microbiological information, treatment, complications, and outcomes. A logistic regression analysis was used to determine the association between different variables and mortality rates.
RESULTS
RESULTS
A total of 345 patients were included in this study. 233 (67.5%) had confirmed PLA, 133 (30%) patients had no positive culture and negative serology and 9 (2.5%) had mixed abscesses. The mean age was 50 years (ranging from 16-97 years) and 63% were female. 65% of the patients had positive cultures for Extended Spectrum Beta-Lactamases (ESBL)-
CONCLUSION
CONCLUSIONS
The prevalence of PLA is increasing in Mexico and has a very high mortality rate. ESBL-
Identifiants
pubmed: 33200019
doi: 10.4254/wjh.v12.i10.816
pmc: PMC7643219
doi:
Types de publication
Journal Article
Langues
eng
Pagination
816-828Informations de copyright
©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
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