A Systematic Review of Nonautologous Graft Materials Used in Human Tympanoplasty.
Tympanoplasty
synthetic graft
tympanic membrane
Journal
The Laryngoscope
ISSN: 1531-4995
Titre abrégé: Laryngoscope
Pays: United States
ID NLM: 8607378
Informations de publication
Date de publication:
02 2021
02 2021
Historique:
received:
22
01
2020
revised:
01
06
2020
accepted:
12
06
2020
pubmed:
12
11
2020
medline:
20
1
2021
entrez:
11
11
2020
Statut:
ppublish
Résumé
Nonautologous graft materials may solve several dilemmas in tympanoplasty by obviating the need for graft harvest, facilitating consistent wound healing, and permitting graft placement in the clinical setting. Prior studies of nonautologous grafts in humans have shown variable outcomes. In this systematic review, we aim to 1) summarize clinical outcomes and 2) discuss limitations in the literature regarding nonautologous grafts for tympanoplasty in humans. A literature review was performed using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations. The study size, etiology and duration of perforation, type of nonautologous graft, and postoperative closure rate were assessed. The PRISMA approach yielded 61 articles, including 3,247 ears that met inclusion criteria. Studies evaluated nonautologous grafts including paper patch, gelatin sponge, growth factors, porcine small-intestinal submucosa, among others. Traumatic perforations (62.3%) were most commonly studied, whereas postinfectious perforations (31.9%) and other etiologies (5.8%) comprised a minority of cases. Acute perforations of <8 weeks duration constituted just over half of all treated ears. Overall closure rate was 82.1%, with significantly higher closure rates in acute (89.9%) versus chronic perforations (64.9%, P < .01), regardless of material. A median postoperative air-bone gap of 5.6 dB was found in the 23% of studies reporting this metric. The majority of publications reviewing nonautologous materials in tympanoplasty evaluate acute or traumatic perforations, and few rigorously report hearing outcomes. Given available data, porcine submucosa and basic fibroblast growth factor may hold promise for chronic perforation closure. Future studies should report closure rates and hearing outcomes in perforations >8 weeks duration. Laryngoscope, 131:392-400, 2021.
Types de publication
Journal Article
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
392-400Informations de copyright
© 2020 The American Laryngological, Rhinological and Otological Society, Inc.
Références
Boedts D, De Cock M, Andries L, Marquet J. A scanning electron-microscopic study of different tympanic grafts. Am J Otol 1990;11:274-277.
House WF, Sheehy JL. Functional restoration in tympanoplasty. Arch Otolaryngol 1963;78:304-309.
Kaylie DM, Gardner EK, Jackson CG. Revision chronic ear surgery. Otolaryngol Head Neck Surg 2006;134:443-450.
Hardman J, Muzaffar J, Nankivell P, Coulson C. Tympanoplasty for chronic tympanic membrane perforation in children: systematic review and meta-analysis. Otol Neurotol 2015;36:796-804.
Tan HE, Santa Maria PL, Eikelboom RH, Anandacoomaraswamy KS, Atlas MD. Type I tympanoplasty meta-analysis: a single variable analysis. Otol Neurotol 2016;37:838-846.
Nardone M, Sommerville R, Bowman J, Danesi G. Myringoplasty in simple chronic otitis media: critical analysis of long-term results in a 1,000-adult patient series. Otol Neurotol 2012;33:48-53.
Iacovou E, Vlastarakos PV, Papacharalampous G, Kyrodimos E, Nikolopoulos TP. Is cartilage better than temporalis muscle fascia in type I tympanoplasty? Implications for current surgical practice. Eur Arch Otorhinolaryngol 2013;270:2803-2813.
Moher D, Liberati A, Tetzlaff J, Altman DG, PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. J Clin Epidemiol 2009;62:1006-1012.
Saliba I, Froehlich P. Hyaluronic acid fat graft myringoplasty: an office-based technique adapted to children. Arch Otolaryngol Head Neck Surg 2011;137:1203-1209.
Howick J, Chalmers I, Glasziou P, et al. The 2011 Oxford CEBM Levels of Evidence (Introductory Document). Oxford, United Kingdom: Oxford Centre For Evidence Based Medicine; 2011.
Slim K, Nini E, Forestier D, Kwiatkowski F, Panis Y, Chipponi J. Methodological index for non-randomized studies (minors): development and validation of a new instrument. ANZ J Surg 2003;73:712-716.
Jin ZH, Dong YH, Lou ZH. The effects of fibroblast growth factor-2 delivered via a Gelfoam patch on the regeneration of myringosclerotic traumatic eardrum perforations lying close to the malleus. Am J Otolaryngol 2017;38:582-587.
Lee JH, Lee JS, Kim DK, Park CH, Lee HR. Clinical outcomes of silk patch in acute tympanic membrane perforation. Clin Exp Otorhinolaryngol 2015;8:117-122.
Park MK, Kim KH, Lee JD, Lee BD. Repair of large traumatic tympanic membrane perforation with a Steri-Strips patch. Otolaryngol Head Neck Surg 2011;145:581-585.
Gur OE, Ensari N, Ozturk MT, et al. Use of a platelet-rich fibrin membrane to repair traumatic tympanic membrane perforations: a comparative study. Acta Otolaryngol 2016;136:1017-1023.
Camnitz PS, Bost WS. Traumatic perforations of the tympanic membrane: early closure with paper tape patching. Otolaryngol Head Neck Surg 1985;93:220-223.
Dursun E, Dogru S, Gungor A, Cincik H, Poyrazoglu E, Ozdemir T. Comparison of paper-patch, fat, and perichondrium myringoplasty in repair of small tympanic membrane perforations. Otolaryngol Head Neck Surg 2008;138:353-356.
Lee DH, Kim J, Shin E, Kim Y, Cho Y. Clinical analysis of paper patch myringoplasty in patients with tympanic membrane perforations. J Int Adv Otol 2016;12:142-146.
Park SN, Kim HM, Jin KS, Maeng JH, Yeo SW, Park SY. Predictors for outcome of paper patch myringoplasty in patients with chronic tympanic membrane perforations. Eur Arch Otorhinolaryngol 2015;272:297-301.
Roosli C, Sim JH, Chatzimichalis M, Huber AM. How does closure of tympanic membrane perforations affect hearing and middle ear mechanics? An evaluation in a patient cohort and temporal bone models. Otol Neurotol 2012;33:371-378.
Simsek G, Akin I. Early paper patching versus observation in patients with traumatic eardrum perforations: comparisons of anatomical and functional outcomes. J Craniofac Surg 2014;25:2030-2032.
Silverstein H, Wycherly BJ, Darley DS, Alameda YA. Mixed hearing loss in iatrogenic tympanic membrane perforations over the round window niche and the immediate effect of paper patch myringoplasty. Audiol Neurootol 2012;17:155-160.
Kronenberg J, Ben-Shoshan J, Wolf M. Perforated tympanic membrane after blast injury. Am J Otol 1993;14:92-94.
Golz A, Goldenberg D, Netzer A, et al. Paper patching for chronic tympanic membrane perforations. Otolaryngol Head Neck Surg 2003;128:565-570.
Rybak LP, Johnson DW. Tympanic membrane perforations from water sports: treatment and outcome. Otolaryngol Head Neck Surg 1983;91:659-662.
Lee SH, Jin SM, Lee KC, Kim MG. Paper-patch myringoplasty with CO2 laser for chronic TM perforation. Eur Arch Otorhinolaryngol 2008;265:1161-1164.
Laurent C, Soderberg O, Anniko M, Hartwig S. Repair of chronic tympanic membrane perforations using applications of hyaluronan or rice paper prostheses. ORL J Otorhinolaryngol Relat Spec 1991;53:37-40.
Merwin GE, Boies LR Jr. Paper patch repair of blast rupture of the tympanic membrane. Laryngoscope 1980;90:853-860.
Roosli C, von Buren T, Gassmann NB, Huber AM. The impact of platelet-derived growth factor on closure of chronic tympanic membrane perforations: a randomized, double-blind, placebo-controlled study. Otol Neurotol 2011;32:1224-1229.
Spandow O, Hellstrom S, Dahlstrom M, Bohlin L. Comparison of the repair of permanent tympanic membrane perforations by hydrocolloidal dressing and paper patch. J Laryngol Otol 1995;109:1041-1047.
Lindeman P, Edstrom S, Granstrom G, et al. Acute traumatic tympanic membrane perforations. Cover or observe? Arch Otolaryngol Head Neck Surg 1987;113:1285-1287.
Cayir S, Mutlu H. Traumatic tympanic membrane perforation in children in the emergency department: comparison of spontaneous closure and paper patch. Cureus 2020;12:e7697.
Hanege FM, Karaca S, Kalcioglu MT, Tekin M. Comparing spontaneous closure and paper patching in traumatic tympanic membrane perforations. J Craniofac Surg 2018;29:1922-1924.
Yan K, Lv M, Xu E, et al. Effectiveness of patching traumatic eardrum perforations with lens cleaning paper via an otoscope. J Laryngol Otol 2017;131:805-808.
Lee JH, Kim DK, Park HS, et al. A prospective cohort study of the silk fibroin patch in chronic tympanic membrane perforation. Laryngoscope 2016;126:2798-2803.
Gaffar Aslan LU. Adhesive strip patching for tympanic membrane perforations. Oper Tech Otolayngol Head Neck Surg 2011;22:173-174.
Saito H, Kazama Y, Yazawa Y. Simple maneuver for closing traumatic eardrum perforation by micropore strip tape patching. Am J Otol 1990;11:427-430.
Huang P, Zhang S, Gong X, Wang X, Lou ZH. Endoscopic observation of different repair patterns in human traumatic tympanic membrane perforations. Braz J Otorhinolaryngol 2018;84:545-552.
Lou ZC, He JG. A randomised controlled trial comparing spontaneous healing, gelfoam patching and edge-approximation plus gelfoam patching in traumatic tympanic membrane perforation with inverted or everted edges. Clin Otolaryngol 2011;36:221-226.
Lou ZC, Lou Z. Efficacy of EGF and gelatin sponge for traumatic tympanic membrane perforations: a randomized controlled study. Otolaryngol Head Neck Surg 2018;159:1028-1036.
Lou ZC, Tang YM, Chen HY, Xiao J. The perforation margin phenotypes and clinical outcome of traumatic tympanic membrane perforation with a Gelfoam patch: our experience from a retrospective study of seventy-four patients. Clin Otolaryngol 2015;40:389-392.
Lou ZC, Wei H, Lou ZH. Comparison of the medical costs and effects of large traumatic eardrum perforations treatment. Am J Otolaryngol 2019;40:46-51.
Niklasson A, Tano K. The Gelfoam(R) plug: an alternative treatment for small eardrum perforations. Laryngoscope 2011;121:782-784.
Singh M, Kaur M, Singh B, Singh K, Singh A, Kaur A. Role of trichloroacetic acid and gelfoam in closure of tympanic membrane perforations. Niger J Clin Pract 2017;20:1233-1236.
Lou ZC. The effects of everted or inverted edges on healing of traumatic-induced tympanic membrane perforations. J Laryngol Otol 2019;133:1092-1096.
Lou ZC, Lou ZH, Liu YC, Chang J. Healing human moderate and large traumatic tympanic membrane perforations using basic fibroblast growth factor, 0.3% ofloxacin eardrops, and Gelfoam patching. Otol Neurotol 2016;37:735-741.
Harris I, Barton S, Gussen R, Goodhill V. Gelfilm-induced neotympanic membrane in tympanoplasty. Laryngoscope 1971;81:1826-1837.
Lou ZC, Xu L, Yang J, Wu X. Outcome of children with edge-everted traumatic tympanic membrane perforations following spontaneous healing versus fibroblast growth factor-containing gelfoam patching with or without edge repair. Int J Pediatr Otorhinolaryngol 2011;75:1285-1288.
Ballivet de Regloix S, Crambert A, Salf E, Maurin O, Pons Y, Clement P. Early tympanoplasty using a synthetic biomembrane for military-related blast induced large tympanic membrane perforation. Mil Med 2018;183:e624-e627.
Prior M, Gibbins N, John G, Rhys-Williams S, Scott P. Hyaluronic acid ester in myringoplasty. J Laryngol Otol 2008;122:e3.
Sayin I, Kaya KH, Ekizoglu O, Erdim I, Kayhan FT. A prospective controlled trial comparing spontaneous closure and Epifilm(R) patching in traumatic tympanic membrane perforations. Eur Arch Otorhinolaryngol 2013;270:2857-2863.
Acharya AN, Coates H, Tavora-Vieira D, Rajan GP. A pilot study investigating basic fibroblast growth factor for the repair of chronic tympanic membrane perforations in pediatric patients. Int J Pediatr Otorhinolaryngol 2015;79:332-335.
Hakuba N, Taniguchi M, Shimizu Y, Sugimoto A, Shinomori Y, Gyo K. A new method for closing tympanic membrane perforations using basic fibroblast growth factor. Laryngoscope 2003;113:1352-1355.
Kanemaru S, Umeda H, Kitani Y, Nakamura T, Hirano S, Ito J. Regenerative treatment for tympanic membrane perforation. Otol Neurotol 2011;32:1218-1223.
Lou ZC, Tang Y, Wu X. Analysis of the effectiveness of basic fibroblast growth factor treatment on traumatic perforation of the tympanic membrane at different time points. Am J Otolaryngol 2012;33:244-249.
Lou ZC, Hu YX, Tang YM. Prognosis and outcome of the tympanic membrane flap at traumatic tympanic membrane perforation edge. ORL J Otorhinolaryngol Relat Spec 2011;73:212-218.
Ramsay HA, Heikkonen EJ, Laurila PK. Effect of epidermal growth factor on tympanic membranes with chronic perforations: a clinical trial. Otolaryngol Head Neck Surg 1995;113:375-379.
Hakuba N, Hato N, Okada M, Mise K, Gyo K. Preoperative factors affecting tympanic membrane regeneration therapy using an atelocollagen and basic fibroblast growth factor. JAMA Otolaryngol Head Neck Surg 2015;141:60-66.
Hakuba N, Hato N, Omotehara Y, Okada M, Gyo K. Epithelial pearl formation following tympanic membrane regeneration therapy using an atelocollagen/silicone membrane and basic fibroblast growth factor: our experience from a retrospective study of one hundred sixteen patients. Clin Otolaryngol 2013;38:394-397.
Hakuba N, Ikemune K, Okada M, Hato N. Use of ambulatory anesthesia with manually assisted ventilation for tympanic membrane regeneration therapy in children. Am J Otolaryngol 2015;36:153-157.
Hakuba N, Iwanaga M, Tanaka S, et al. Basic fibroblast growth factor combined with atelocollagen for closing chronic tympanic membrane perforations in 87 patients. Otol Neurotol 2010;31:118-121.
Kanemaru SI, Kanai R, Yoshida M, Kitada Y, Omae K, Hirano S. Application of regenerative treatment for tympanic membrane perforation with cholesteatoma, tumor, or severe calcification. Otol Neurotol 2018;39:438-444.
Lou ZC. Healing large traumatic eardrum perforations in humans using fibroblast growth factor applied directly or via gelfoam. Otol Neurotol 2012;33:1553-1557.
Omae K, Kanemaru SI, Nakatani E, et al. Regenerative treatment for tympanic membrane perforation using gelatin sponge with basic fibroblast growth factor. Auris Nasus Larynx 2017;44:664-671.
Santos F, Shu E, Lee DJ, et al. Topical fibroblast growth factor-2 for treatment of chronic tympanic membrane perforations. Laryngoscope Investig Otolaryngol 2020;1-8.
Biskin S, Damar M, Oktem SN, Sakalli E, Erdem D, Pakir O. A new graft material for myringoplasty: bacterial cellulose. Eur Arch Otorhinolaryngol 2016;273:3561-3565.
Mandour YMH, Mohammed S, Menem MOA. Bacterial cellulose graft versus fat graft in closure of tympanic membrane perforation. Am J Otolaryngol 2019;40:168-172.
Silveira FC, Pinto FC, Caldas Neto Sda S, Leal Mde C, Cesario J, Aguiar JL. Treatment of tympanic membrane perforation using bacterial cellulose: a randomized controlled trial. Braz J Otorhinolaryngol 2016;82:203-208.
Tamae A, Komune S. Clinical study of transcanal closure of tympanic membrane perforations using a collagen sponge. J Laryngol Otol 2015;129:S21-S26.
D'Eredita R. Porcine small intestinal submucosa (SIS) myringoplasty in children: a randomized controlled study. Int J Pediatr Otorhinolaryngol 2015;79:1085-1089.
Kozin ED, Lee DJ, Remenschneider AK. Bilayer graft for incisionless in-office endoscopic repair of tympanic membrane perforations: a pilot study. OTO Open 2019;3:2473974X19869911.
Branica S, Dawidowsky K, Kovac-Bilic L, Bilic M. Silicon foil patching for blast tympanic membrane perforation: a retrospective study. Croat Med J 2019;60:503-507.
Hempel JM, Becker A, Muller J, Krause E, Berghaus A, Braun T. Traumatic tympanic membrane perforations: clinical and audiometric findings in 198 patients. Otol Neurotol 2012;33:1357-1362.