Forensic NMR metabolomics: one more arrow in the quiver.
1H NMR
Biological traces
Drug abuse
Forensics
Metabolomics
Post-mortem interval
Journal
Metabolomics : Official journal of the Metabolomic Society
ISSN: 1573-3890
Titre abrégé: Metabolomics
Pays: United States
ID NLM: 101274889
Informations de publication
Date de publication:
07 11 2020
07 11 2020
Historique:
received:
17
04
2020
accepted:
29
10
2020
entrez:
7
11
2020
pubmed:
8
11
2020
medline:
10
7
2021
Statut:
epublish
Résumé
NMR metabolomics is increasingly used in forensics, due to the possibility of investigating both endogenous metabolic profiles and exogenous molecules that may help to describe metabolic patterns and their modifications associated to specific conditions of forensic interest. The aim of this work was to review the recent literature and depict the information provided by NMR metabolomics. Attention has been devoted to the identification of peculiar metabolic signatures and specific ante-mortem and post-mortem profiles or biomarkers related to different conditions of forensic concern, such as the identification of biological traces, the estimation of the time since death, and the exposure to drugs of abuse. The results of the described studies highlight how forensics can benefit from NMR metabolomics by gaining additional information that may help to shed light in several forensic issues that still deserve to be further elucidated.
Identifiants
pubmed: 33159593
doi: 10.1007/s11306-020-01743-6
pii: 10.1007/s11306-020-01743-6
pmc: PMC7648736
doi:
Substances chimiques
Biomarkers
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
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