Risk for Premature Mortality and Intentional Self-harm in Autism Spectrum Disorders.
Autism
Mortality
Natural cause
Psychiatric disorders
Suicide
Journal
Journal of autism and developmental disorders
ISSN: 1573-3432
Titre abrégé: J Autism Dev Disord
Pays: United States
ID NLM: 7904301
Informations de publication
Date de publication:
Sep 2021
Sep 2021
Historique:
accepted:
22
10
2020
pubmed:
4
11
2020
medline:
20
8
2021
entrez:
3
11
2020
Statut:
ppublish
Résumé
To examine the risk for premature mortality and intentional self-harm in autism spectrum disorders (ASD). Based on a national birth cohort. Children born in 1987-2005, diagnosed with ASD by 2007 (n = 4695) were matched with four non-ASD subjects (n = 18,450) and followed until 2015 for mortality and intentional self-harm. The risk among ASD subjects was elevated only for natural cause of death. The risk for intentional self-harm was increased in the unadjusted analyses, but decreased to non-significant after adjusting for comorbid psychiatric disorders. ASD subjects are at increased risk for premature mortality due to natural causes of death. While ASD subjects die of suicide and present with more self-harm, the association is explained by comorbid psychiatric disorders.
Identifiants
pubmed: 33140146
doi: 10.1007/s10803-020-04768-x
pii: 10.1007/s10803-020-04768-x
pmc: PMC8349316
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
3098-3108Subventions
Organisme : American Foundation for Suicide Prevention
ID : DIG-1-139-15
Organisme : Academy of Finland Flagship Programme
ID : decision number: 320162
Organisme : Strategic Research Council at the Academy of Finland
ID : decision number: 303581
Organisme : Academy of Finland Health from Cohorts and Biobanks Programme
ID : decision number: 308552
Organisme : Brain and Behavior Research Foundation
ID : -
Organisme : Academy of Finland
ID : -
Organisme : Finnish Medical Foundation
ID : -
Organisme : Brain and Behavior Research Foundation
Organisme : Academy of Finland
Organisme : Finnish Medical Foundation
Informations de copyright
© 2020. The Author(s).
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