Role of the Mitochondrial Pyruvate Carrier in the Occurrence of Metabolic Inflexibility in
Drosophila
homeostasis
metabolic inflexibility
metabolomics
mitochondrial pyruvate carrier
mitochondrial respiration
sucrose
Journal
Metabolites
ISSN: 2218-1989
Titre abrégé: Metabolites
Pays: Switzerland
ID NLM: 101578790
Informations de publication
Date de publication:
14 Oct 2020
14 Oct 2020
Historique:
received:
11
09
2020
revised:
01
10
2020
accepted:
10
10
2020
entrez:
17
10
2020
pubmed:
18
10
2020
medline:
18
10
2020
Statut:
epublish
Résumé
Excess dietary carbohydrates are linked to dysregulation of metabolic pathways converging to mitochondria and metabolic inflexibility. Here, we determined the role of the mitochondrial pyruvate carrier (MPC) in the occurrence of this metabolic inflexibility in wild-type (WT) and MPC1-deficient (MPC1
Identifiants
pubmed: 33066485
pii: metabo10100411
doi: 10.3390/metabo10100411
pmc: PMC7602203
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Natural Sciences and Engineering Research Council of Canada
ID : RGPIN-2017-05100
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