Induction of Combination Therapy for the Management of Hepatitis C: An Observational Study.
hepatitis c
interferon
rapid virological response
ribavirin
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
05 Sep 2020
05 Sep 2020
Historique:
entrez:
12
10
2020
pubmed:
13
10
2020
medline:
13
10
2020
Statut:
epublish
Résumé
Background and objective Hepatitis C infection is prevalent in Pakistan. The purpose of this study was to observe the therapeutic effects of conventional interferon in combination with ribavirin among treatment-naive hepatitis C patients. Methods This descriptive cross-sectional study of hepatitis C combination therapy was conducted at our institute after approval. All the patients received treatment with conventional interferon (5-MU three times weekly) and ribavirin (1000mg/day) for four weeks. A follow-up for the rapid virological response (RVR) was done in the fourth week of treatment. Results The mean age of the patients was 37.43. There was a gradual decrease in RVR with increasing age after four weeks of treatment. Conclusion The combination therapy showed good RVR in the fourth week among all hepatitis C patients.
Identifiants
pubmed: 33042697
doi: 10.7759/cureus.10259
pmc: PMC7536117
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e10259Informations de copyright
Copyright © 2020, Khan et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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