Sodium Intake Is Associated With Renal Resistive Index in an Adult Population-Based Study.
Adult
Arteries
/ drug effects
Blood Pressure
/ drug effects
Cross-Sectional Studies
Female
Humans
Hypertension
/ physiopathology
Kidney
/ diagnostic imaging
Male
Middle Aged
Population Surveillance
/ methods
Pulse Wave Analysis
Sodium Chloride, Dietary
/ administration & dosage
Switzerland
Ultrasonography, Doppler
Vascular Resistance
/ drug effects
Vascular Stiffness
/ drug effects
aldosterone
blood pressure
hypertension
renin
sodium vascular stiffness
Journal
Hypertension (Dallas, Tex. : 1979)
ISSN: 1524-4563
Titre abrégé: Hypertension
Pays: United States
ID NLM: 7906255
Informations de publication
Date de publication:
12 2020
12 2020
Historique:
pubmed:
6
10
2020
medline:
4
5
2021
entrez:
5
10
2020
Statut:
ppublish
Résumé
Renal resistive index (RRI) has been associated with adverse renal and cardiovascular outcomes. Although traditionally considered a marker of intrinsic renal damage, RRI could also reflect systemic vascular dysfunction. As sodium intake was linked to alterations in vascular properties, we wished to characterize the association of salt consumption with RRI in the general adult population. Participants were recruited in a population-based study in Switzerland. RRI was measured by ultrasound in 3 segmental arteries. Sodium intake (UNa; mmol/24 h) was estimated on 24-hour urine samples. Carotido-femoral pulse wave velocity was obtained by applanation tonometry. Mixed multivariate regression models were used with RRI or pulse wave velocity as independent variables and UNa as dependent variable, adjusting for possible confounders. We included 1002 patients in the analyses with 528 (52.7%) women and mean age of 47.2±17.4. Mean values of UNa and RRI were 141.8±61.1 mmol/24 h and 63.8±5.5%, respectively. In multivariate analysis, UNa was positively associated with RRI (
Identifiants
pubmed: 33012201
doi: 10.1161/HYPERTENSIONAHA.120.15932
doi:
Substances chimiques
Sodium Chloride, Dietary
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM