Pathogenesis of Eosinophilic Esophagitis: A Comprehensive Review of the Genetic and Molecular Aspects.

Calpain / genetics Chemokine CCL26 / genetics Cytokines / genetics Eosinophilic Esophagitis / genetics Esophagus / pathology Genetic Predisposition to Disease Genome-Wide Association Study Humans Hypersensitivity / complications Interleukin-13 / genetics Th2 Cells / metabolism Transforming Growth Factor beta1 / genetics
genetic susceptibility pathophysiology polymorphism

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
30 Sep 2020
Historique:
received: 01 08 2020
revised: 24 09 2020
accepted: 28 09 2020
entrez: 3 10 2020
pubmed: 4 10 2020
medline: 24 2 2021
Statut: epublish

Résumé

Eosinophilic esophagitis (EoE) is a relatively new condition described as an allergic-mediated disease of the esophagus. Clinically, it is characterized by dysphagia, food impaction, and reflux-like symptoms. Multiple genome-wide association studies (GWAS) have been conducted to identify genetic loci associated with EoE. The integration of numerous studies investigating the genetic polymorphisms in EoE and the Mendelian diseases associated with EoE are discussed to provide insights into the genetic risk of EoE, notably focusing on

Identifiants

DOI: 10.3390/ijms21197253 PMID: 33008138 PMC: PMC7582808
pubmed: 33008138
pii: ijms21197253
doi: 10.3390/ijms21197253
pmc: PMC7582808
pii:
doi:

Substances chimiques

CCL26 protein, human 0
Chemokine CCL26 0
Cytokines 0
IL13 protein, human 0
Interleukin-13 0
TGFB1 protein, human 0
TSLP protein, human 0
Transforming Growth Factor beta1 0
CAPN14 protein, human EC 3.4.22.-
Calpain EC 3.4.22.-

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Références

Gastroenterology. 2008 Jan;134(1):204-14
pubmed: 18166354
J Allergy Clin Immunol. 2013 Jun;131(6):1576-82
pubmed: 23623266
Gastroenterology. 2014 May;146(5):1266-77.e1-9
pubmed: 24486052
BMC Gastroenterol. 2013 May 30;13:96
pubmed: 23721294
Biochim Biophys Acta. 2016 Apr;1863(4):572-80
pubmed: 26775586
J Allergy Clin Immunol. 2016 Nov;138(5):1367-1380.e5
pubmed: 27233150
J Leukoc Biol. 2007 Apr;81(4):916-24
pubmed: 17194734
J Allergy Clin Immunol. 2013 Aug;132(2):378-86
pubmed: 23608731
J Allergy Clin Immunol. 2001 Oct;108(4):503-8
pubmed: 11590372
J Immunol. 2010 Jul 1;185(1):660-9
pubmed: 20543112
United European Gastroenterol J. 2017 Apr;5(3):335-358
pubmed: 28507746
Clin Rev Allergy Immunol. 2018 Aug;55(1):19-42
pubmed: 29332138
Am J Physiol Gastrointest Liver Physiol. 2012 Apr;302(7):G645-54
pubmed: 22207581
J Invest Dermatol. 2009 Mar;129(3):543-52
pubmed: 19209157
Nat Genet. 2014 Aug;46(8):895-900
pubmed: 25017104
J Allergy Clin Immunol. 2015 Jul;136(1):59-68.e14
pubmed: 25617223
Nat Med. 2013 Aug;19(8):1005-13
pubmed: 23872715
Nat Immunol. 2011 Sep 11;12(11):1055-62
pubmed: 21909091
Nat Commun. 2014 Nov 19;5:5593
pubmed: 25407941
JCI Insight. 2018 Apr 19;3(8):
pubmed: 29669943
PLoS One. 2015 May 28;10(5):e0128346
pubmed: 26020633
Pediatr Clin North Am. 2019 Oct;66(5):955-965
pubmed: 31466684
J Pediatr Gastroenterol Nutr. 2011 Oct;53(4):409-16
pubmed: 21970996
J Allergy Clin Immunol. 2017 Oct;140(4):1138-1143
pubmed: 28192145
Clin Exp Allergy. 2014 Jan;44(1):58-68
pubmed: 24118614
Eur J Immunol. 2011 Jul;41(7):1862-71
pubmed: 21484783
Clin Transl Gastroenterol. 2016 Mar 17;7:e155
pubmed: 26986655
Nat Med. 2009 Apr;15(4):410-6
pubmed: 19330007
J Allergy Clin Immunol. 2015 Sep;136(3):792-794.e3
pubmed: 26233928
J Allergy Clin Immunol. 2017 Jun;139(6):2003-2005.e1
pubmed: 28025013
Gastroenterology. 1978 Jun;74(6):1298-1301
pubmed: 648822
Annu Rev Immunol. 2007;25:297-336
pubmed: 17150027
Ann N Y Acad Sci. 2016 Sep;1380(1):204-217
pubmed: 27467185
Am J Surg Pathol. 2017 May;41(5):616-621
pubmed: 28296675
J Allergy Clin Immunol. 2014 May;133(5):1471-4
pubmed: 24472624
Mucosal Immunol. 2010 Mar;3(2):138-47
pubmed: 20016474
Schweiz Med Wochenschr. 1994 Aug 20;124(33):1419-29
pubmed: 7939509
G3 (Bethesda). 2019 Mar 7;9(3):729-736
pubmed: 30626591
J Allergy Clin Immunol. 2017 Jun;139(6):2010-2013.e4
pubmed: 28063872
Clin Transl Immunology. 2014 Jan 10;3(1):e9
pubmed: 25505954
Dig Dis Sci. 2006 Nov;51(11):1934-41
pubmed: 17009121
Am J Physiol Gastrointest Liver Physiol. 2012 Jun 1;302(11):G1347-55
pubmed: 22361731
Invest Ophthalmol Vis Sci. 2014 Mar 06;55(3):1339-47
pubmed: 24526444
J Allergy Clin Immunol. 2014 May;133(5):1487-9, 1489.e1
pubmed: 24636092
Immun Inflamm Dis. 2014 Jun;2(1):44-55
pubmed: 25400924
PLoS Genet. 2015 Sep 21;11(9):e1005389
pubmed: 26390218
J Immunol. 2010 Apr 1;184(7):4033-41
pubmed: 20208004
Immunol Allergy Clin North Am. 2015 Feb;35(1):145-59
pubmed: 25459582
Eur J Immunol. 2011 Jun;41(6):1535-8
pubmed: 21618506
Gastrointest Endosc Clin N Am. 2018 Jan;28(1):1-14
pubmed: 29129294
Nat Immunol. 2009 Dec;10(12):1283-91
pubmed: 19898472
Ann Clin Lab Sci. 2009 Spring;39(2):99-107
pubmed: 19429794
Nat Rev Drug Discov. 2007 Apr;6(4):313-25
pubmed: 17396136
Gastroenterology. 2010 Nov;139(5):1526-37, 1537.e1
pubmed: 20682320
J Allergy Clin Immunol. 2006 Nov;118(5):1054-9
pubmed: 17088129
Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):9755-60
pubmed: 12119397
Genes Immun. 2019 Apr;20(4):281-292
pubmed: 29904099
J Dermatol. 1989 Aug;16(4):255-62
pubmed: 2689488
J Allergy Clin Immunol. 2016 Mar;137(3):907-18.e9
pubmed: 26431580
N Engl J Med. 2015 Oct 22;373(17):1640-8
pubmed: 26488694
Nat Rev Immunol. 2013 May;13(5):362-75
pubmed: 23558889
Front Oncol. 2015 Feb 16;5:24
pubmed: 25763354
Clin Exp Allergy. 2005 Aug;35(8):1096-103
pubmed: 16120093
Expert Opin Emerg Drugs. 2018 Jun;23(2):173-183
pubmed: 29848130
J Allergy Clin Immunol. 2007 Dec;120(6):1292-300
pubmed: 18073124
Nat Genet. 2010 Apr;42(4):289-91
pubmed: 20208534
J Allergy Clin Immunol. 2012 May;129(5):1387-1396.e7
pubmed: 22465212
Aliment Pharmacol Ther. 2019 May;49(9):1116-1125
pubmed: 30887555
Nature. 2011 Aug 14;477(7363):229-33
pubmed: 21841801
Gut. 2010 Jan;59(1):21-30
pubmed: 19828470
Arch Pediatr. 2019 Apr;26(3):182-190
pubmed: 30827775
Am J Gastroenterol. 2012 May;107(5):698-706
pubmed: 22310220
J Allergy Clin Immunol. 2014 Nov;134(5):1100-1107.e4
pubmed: 24835503
J Allergy Clin Immunol. 2001 Dec;108(6):954-61
pubmed: 11742273
Science. 2012 Apr 27;336(6080):489-93
pubmed: 22442383
Gastroenterology. 2018 Oct;155(4):1022-1033.e10
pubmed: 30009819
Inflamm Bowel Dis. 2005 Aug;11(8):720-6
pubmed: 16043986
Rev Esp Enferm Dig. 2014 May;106(5):334-45
pubmed: 25287236
J Allergy Clin Immunol. 2008 Jun;121(6):1311-20; quiz 1321-2
pubmed: 18539190
J Allergy Clin Immunol. 2013 Jun;131(6):1583-5
pubmed: 23726533
J Allergy Clin Immunol. 2010 Jul;126(1):140-9
pubmed: 20538331
Traffic. 2016 Jul;17(7):709-19
pubmed: 27103185
J Allergy Clin Immunol. 2018 Jul;142(1):139-148.e12
pubmed: 29678750
Am J Physiol Gastrointest Liver Physiol. 2018 Nov 1;315(5):G879-G886
pubmed: 30212252
J Allergy Clin Immunol. 2015 Feb;135(2):500-7
pubmed: 25226850
J Pediatr Gastroenterol Nutr. 2014 Jul;59(1):10-6
pubmed: 24590208
J Exp Med. 2017 Mar 6;214(3):669-680
pubmed: 28126831
J Allergy Clin Immunol. 2018 Jan;141(1):214-222
pubmed: 28601683
J Allergy Clin Immunol. 2017 Sep;140(3):738-749.e3
pubmed: 28104354
Mucosal Immunol. 2015 Sep;8(5):1154-65
pubmed: 25712805
Gastroenterology. 2015 May;148(6):1143-57
pubmed: 25666870
J Clin Invest. 2006 Feb;116(2):536-47
pubmed: 16453027
J Allergy Clin Immunol. 2015 Oct;136(4):971-82
pubmed: 25981737
Gastroenterology. 2002 May;122(5):1216-25
pubmed: 11984507
Am J Physiol Gastrointest Liver Physiol. 2013 Jun 15;304(12):G1087-94
pubmed: 23599040
Immunol Cell Biol. 2013 Jul;91(6):408-15
pubmed: 23689305
J Allergy Clin Immunol. 2016 Mar;137(3):919-21
pubmed: 26947983
J Biol Chem. 2011 Mar 4;286(9):7507-21
pubmed: 21187289
Arch Dis Child. 2015 Jan;100(1):57-61
pubmed: 24994860
Allergy. 2015 Apr;70(4):443-52
pubmed: 25620273
J Allergy Clin Immunol. 2010 Jul;126(1):112-9
pubmed: 20620567
Annu Rev Pathol. 2016 May 23;11:365-93
pubmed: 26925500
Gastroenterology. 2018 Jan;154(2):333-345
pubmed: 28757265
J Exp Med. 2014 Dec 15;211(13):2549-66
pubmed: 25422492
J Allergy Clin Immunol. 2010 Dec;126(6):1198-204.e4
pubmed: 21047675
Am J Gastroenterol. 2013 May;108(5):679-92; quiz 693
pubmed: 23567357
Curr Opin Immunol. 2017 Oct;48:114-121
pubmed: 28965008
Hum Mutat. 2015 May;36(5):535-47
pubmed: 25703627
J Pediatr Gastroenterol Nutr. 2013 Mar;56(3):242
pubmed: 23132165
Mucosal Immunol. 2014 May;7(3):718-29
pubmed: 24220297
Immunol Cell Biol. 2015 Nov;93(10):849-57
pubmed: 25801352
PLoS One. 2016 Mar 18;11(3):e0150968
pubmed: 26992000
Gastroenterology. 2010 Jul;139(1):182-93.e7
pubmed: 20381491
J Allergy Clin Immunol. 2020 Jan;145(1):9-15
pubmed: 31910986
Gastroenterology. 2014 Sep;147(3):602-9
pubmed: 24907494
Am J Surg Pathol. 2007 Apr;31(4):598-606
pubmed: 17414108
J Allergy Clin Immunol. 2017 Jun;139(6):1762-1771.e7
pubmed: 28131390
Sci Transl Med. 2013 Jul 24;5(195):195ra94
pubmed: 23884466
Genes Immun. 2014 Sep;15(6):361-9
pubmed: 24920534
Clin J Gastroenterol. 2017 Apr;10(2):87-102
pubmed: 28247277
Dis Esophagus. 2014 Aug;27(6):601-6
pubmed: 24165271
J Allergy Clin Immunol. 2011 Jul;128(1):23-32; quiz 33-4
pubmed: 21570716
J Pediatr Gastroenterol Nutr. 2011 Mar;52(3):300-6
pubmed: 21057327
J Allergy Clin Immunol. 2007 Jan;119(1):206-12
pubmed: 17208603
Mucosal Immunol. 2017 May;10(3):580-588
pubmed: 28224995

Auteurs

Seohyun Ryu (S)

Yonsei University College of Medicine, 03722 Seoul, Korea.

Keum Hwa Lee (KH)

Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
ORCID: 0000-0002-1511-9587

Kalthoum Tizaoui (K)

Laboratory Microorganismes and Active Biomolecules, Sciences Faculty of Tunis, University Tunis El Manar, 1068 Tunis, Tunisia.

Salvatore Terrazzino (S)

Department of Pharmaceutical Sciences and Interdepartmental Research Center of Pharmacogenetics and Pharmacogenomics (CRIFF), University of Piemonte Orientale, 28100 Novara, Italy.
ORCID: 0000-0002-4909-1121

Sarah Cargnin (S)

Department of Pharmaceutical Sciences and Interdepartmental Research Center of Pharmacogenetics and Pharmacogenomics (CRIFF), University of Piemonte Orientale, 28100 Novara, Italy.
ORCID: 0000-0001-6242-7817

Maria Effenberger (M)

Department of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology and Metabolism, Medical University of Innsbruck, 6020 Innsbruck, Austria.

Jae Il Shin (JI)

Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
ORCID: 0000-0003-2326-1820

Andreas Kronbichler (A)

Department of Internal Medicine IV (Nephrology and Hypertension), Medical University Innsbruck, 6020 Innsbruck, Austria.
ORCID: 0000-0002-2945-2946

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

Recherchemedicale.com › Enzymes et coenzymes › Enzymes › Hydrolases › Peptide hydrolases › Endopeptidases › Cysteine endopeptidases › Calpain › Pathogenesis of Eosinophilic Esophagitis: A...
Recherchemedicale.com › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Chimiokines › Chimiokines CC › Chimiokine CCL26 › Pathogenesis of Eosinophilic Esophagitis: A...
Recherchemedicale.com › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Pathogenesis of Eosinophilic Esophagitis: A...
Recherchemedicale.com › Maladies du système immunitaire › Hypersensibilité › Hypersensibilité immédiate › Oesophagite à éosinophiles › Pathogenesis of Eosinophilic Esophagitis: A...
Recherchemedicale.com › Système digestif › Tube digestif › Tube digestif supérieur › Oesophage › Pathogenesis of Eosinophilic Esophagitis: A...
Recherchemedicale.com › Phénomènes génétiques › Génotype › Prédisposition génétique à une maladie › Pathogenesis of Eosinophilic Esophagitis: A...
Recherchemedicale.com › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Épidémiologie moléculaire › Étude d'association pangénomique › Pathogenesis of Eosinophilic Esophagitis: A...
Recherchemedicale.com › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Pathogenesis of Eosinophilic Esophagitis: A...
Recherchemedicale.com › Maladies du système immunitaire › Hypersensibilité › Pathogenesis of Eosinophilic Esophagitis: A...
Recherchemedicale.com › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Interleukines › Interleukine-13 › Pathogenesis of Eosinophilic Esophagitis: A...
Recherchemedicale.com › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › Sous-populations de lymphocytes T › Lymphocytes T auxiliaires › Lymphocytes auxiliaires Th2 › Pathogenesis of Eosinophilic Esophagitis: A...
Recherchemedicale.com › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Protéines de la superfamille du TGF bêta › Facteur de croissance transformant bêta › Facteur de croissance transformant bêta-1 › Pathogenesis of Eosinophilic Esophagitis: A...