Obesity across the lifespan in congenital heart disease survivors: Prevalence and correlates.


Journal

Heart & lung : the journal of critical care
ISSN: 1527-3288
Titre abrégé: Heart Lung
Pays: United States
ID NLM: 0330057

Informations de publication

Date de publication:
Historique:
received: 09 04 2020
revised: 06 08 2020
accepted: 20 08 2020
pubmed: 28 9 2020
medline: 5 3 2021
entrez: 27 9 2020
Statut: ppublish

Résumé

Congenital heart disease (CHD) survivors are at risk for cardiovascular comorbidities exacerbated by obesity. Determine relationships between overweight/obesity and medical factors across the lifespan of CHD. Lesion severity, weight, blood pressure, cardiac and other comorbidities, and cardiac medications were abstracted from the medical records of 3790 CHD patients, aged ≥6 years, who attended CHD care in the Midwestern U.S. The proportion of patients with overweight/obesity increased across the lifespan, with 73% of adults affected by overweight/obesity. Obesity was more prevalent among patients with moderate lesions (29%). Overweight/obesity was associated with elevated blood pressure across age and lesion severity. Young adults with obesity and simple or moderate lesions had more comorbidities (simple: IRR = 3.1, moderate: IRR = 2.3) and cardiac medications (simple: IRR = 2.2, moderate: IRR = 1.7). Obesity and its cardiovascular correlates are present across the lifespan for CHD survivors, highlighting the need for early prevention and intervention.

Sections du résumé

BACKGROUND
Congenital heart disease (CHD) survivors are at risk for cardiovascular comorbidities exacerbated by obesity.
OBJECTIVES
Determine relationships between overweight/obesity and medical factors across the lifespan of CHD.
METHODS
Lesion severity, weight, blood pressure, cardiac and other comorbidities, and cardiac medications were abstracted from the medical records of 3790 CHD patients, aged ≥6 years, who attended CHD care in the Midwestern U.S.
RESULTS
The proportion of patients with overweight/obesity increased across the lifespan, with 73% of adults affected by overweight/obesity. Obesity was more prevalent among patients with moderate lesions (29%). Overweight/obesity was associated with elevated blood pressure across age and lesion severity. Young adults with obesity and simple or moderate lesions had more comorbidities (simple: IRR = 3.1, moderate: IRR = 2.3) and cardiac medications (simple: IRR = 2.2, moderate: IRR = 1.7).
CONCLUSIONS
Obesity and its cardiovascular correlates are present across the lifespan for CHD survivors, highlighting the need for early prevention and intervention.

Identifiants

pubmed: 32980629
pii: S0147-9563(20)30363-0
doi: 10.1016/j.hrtlng.2020.08.020
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

788-794

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors have no conflicts to declare.

Auteurs

Jamie L Jackson (JL)

Center for Biobehavioral Health, Nationwide Children's Hospital, Near East Office Building, 3(rd) Floor, 431 S. 18(th) St., Columbus, OH 43205, USA; Department of Pediatrics, The Ohio State University, 370 W. 9th Ave., Columbus, OH 43210, USA. Electronic address: Jamie.Jackson2@nationwidechildrens.org.

Kristen R Fox (KR)

Center for Biobehavioral Health, Nationwide Children's Hospital, Near East Office Building, 3(rd) Floor, 431 S. 18(th) St., Columbus, OH 43205, USA. Electronic address: Kristen.Fox@nationwidechildrens.org.

Jennifer Cotto (J)

Center for Biobehavioral Health, Nationwide Children's Hospital, Near East Office Building, 3(rd) Floor, 431 S. 18(th) St., Columbus, OH 43205, USA.

Tondi M Harrison (TM)

College of Nursing, The Ohio State University, 1585 Neil Ave., Columbus, OH 43210, USA. Electronic address: harrison.473@osu.edu.

Andrew H Tran (AH)

Department of Pediatrics, The Ohio State University, 370 W. 9th Ave., Columbus, OH 43210, USA; The Heart Center, Nationwide Children's Hospital, 700 Children's Dr., Columbus, OH 43205, USA. Electronic address: Andrew.Tran@nationwidechilrens.org.

Sarah A Keim (SA)

Center for Biobehavioral Health, Nationwide Children's Hospital, Near East Office Building, 3(rd) Floor, 431 S. 18(th) St., Columbus, OH 43205, USA; Department of Pediatrics, The Ohio State University, 370 W. 9th Ave., Columbus, OH 43210, USA; Division of Epidemiology, College of Public Health, The Ohio State University, 1841 Neil Ave, Columbus, OH 43210, USA. Electronic address: Sarah.Keim@nationwidechildrens.org.

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