Granuloma Annulare, a Possible Paradoxical Reaction of the Adalimumab Treatment in a Severe Case of Psoriasis Vulgaris.

Psoriasis anti TNF α agents granuloma annulare paradoxical reaction

Journal

Current health sciences journal
ISSN: 2067-0656
Titre abrégé: Curr Health Sci J
Pays: Romania
ID NLM: 101597164

Informations de publication

Date de publication:
Historique:
received: 25 06 2018
accepted: 21 03 2020
entrez: 3 9 2020
pubmed: 3 9 2020
medline: 3 9 2020
Statut: ppublish

Résumé

Granuloma annulare (GA) is a benign chronic inflammatory dermatosis, self-limited, slightly pruritic or asymptomatic in the majority of the cases, with specific clinically and histologically features, that occurs in all age groups, but it is rare in infancy. GA is associated to five clinical variants: localized, generalized, perforating, subcutaneous and arcuate dermal erythema. The etiology of GA is usually unknown, but in 60-75% of the cases it is associated with metabolic disorders (diabetes mellitus, dyslipidemia), thyroid disorders, neoplasms, infections or drug induced. We present a psoriasis case treated with anti TNFα agents, Adalimumab, that after three and a half years of treatment developed GA.

Identifiants

pubmed: 32874695
doi: 10.12865/CHSJ.46.02.16
pii: 2020.2.16
pmc: PMC7445640
doi:

Types de publication

Journal Article

Langues

eng

Pagination

203-206

Informations de copyright

Copyright © 2014, Medical University Publishing House Craiova.

Références

Rom J Morphol Embryol. 2013;54(2):327-31
pubmed: 23771077
Biologics. 2007 Jun;1(2):93-103
pubmed: 19707319
Br J Dermatol. 2002 Jan;146(1):122-4
pubmed: 11841378
J Am Acad Dermatol. 2016 Sep;75(3):457-465
pubmed: 27543209
Ther Clin Risk Manag. 2008 Apr;4(2):345-51
pubmed: 18728850
Case Rep Dermatol Med. 2017;2017:5918708
pubmed: 28611928
G Ital Dermatol Venereol. 2014 Jun;149(3):329-33
pubmed: 24819760
Clin Exp Dermatol. 1994 May;19(3):210-6
pubmed: 8033378
Indian J Dermatol. 2011 Nov;56(6):752-4
pubmed: 22345789
Ann Rheum Dis. 2008 Apr;67(4):567-70
pubmed: 17728330
Arch Dermatol. 2012 Oct;148(10):1131-6
pubmed: 22710282

Auteurs

Florentina MĂrculescu (F)

University of Medicine and Pharmacy of Craiova, Romania.

Virgil PĂtraȘcu (V)

University of Medicine and Pharmacy of Craiova, Romania.

Cristina Violeta Tutunaru (CV)

University of Medicine and Pharmacy of Craiova, Romania.

Lavinia Ochiana (L)

University of Medicine and Pharmacy of Craiova, Romania.

Classifications MeSH