Low PCSK-9 levels Are Associated with Favorable Neurologic Function after Resuscitation from out of Hospital Cardiac Arrest.
cardiac arrest
cardiopulmonary resuscitation
critical care outcomes
emergency medicine
inflammation mediators
lipid metabolism
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
11 Aug 2020
11 Aug 2020
Historique:
received:
15
06
2020
revised:
27
07
2020
accepted:
07
08
2020
entrez:
16
8
2020
pubmed:
17
8
2020
medline:
17
8
2020
Statut:
epublish
Résumé
Endotoxemia after cardiopulmonary resuscitation (CPR) is associated with unfavorable outcome. Proprotein convertase subtilisin/kexin type-9 (PCSK-9) regulates low-density lipoprotein receptors, which mediate the hepatic uptake of endotoxins. We hypothesized that PCSK-9 concentrations are associated with neurological outcome in patients after CPR. Successfully resuscitated out-of-hospital cardiac arrest patients were included prospectively (
Identifiants
pubmed: 32796672
pii: jcm9082606
doi: 10.3390/jcm9082606
pmc: PMC7465607
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Austrian Science Funds
ID : SFB54P04
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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