Involvement of sodium-coupled neutral amino acid transporters (system A) in l-proline transport in the rat retinal pericytes.
ATA2
BRB
L-Pro
L-Pro transport
Retinal pericytes
System A
Journal
Drug metabolism and pharmacokinetics
ISSN: 1880-0920
Titre abrégé: Drug Metab Pharmacokinet
Pays: England
ID NLM: 101164773
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
received:
16
03
2020
revised:
02
06
2020
accepted:
09
06
2020
pubmed:
11
8
2020
medline:
2
1
2021
entrez:
11
8
2020
Statut:
ppublish
Résumé
The retinal pericytes contribute to the supply of collagen to the basement membrane, and thus, form the structural support of the blood-retinal barrier. Since l-proline (L-Pro) is a major component of collagen, the uptake of L-Pro is an important process for the synthesis of collagen. This study was aimed to elucidate L-Pro transport mechanism(s) in the retinal pericytes. The transport of [
Identifiants
pubmed: 32771261
pii: S1347-4367(20)30376-1
doi: 10.1016/j.dmpk.2020.06.003
pii:
doi:
Substances chimiques
Amino Acid Transport Systems, Neutral
0
Proline
9DLQ4CIU6V
Sodium
9NEZ333N27
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
410-416Informations de copyright
Copyright © 2020 The Japanese Society for the Study of Xenobiotics. Published by Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest There are no conflicts of interest to declare.